Author Archives: Megan Thomas

#Genome sequencing #Genomics #Podcasts

Podcast: What can we learn from the genome?  

This is the latest episode of the free DDW podcast, “What can we learn from the genome?”. It covers two narrated articles written for Volume 22, Issue 3 – Summer 2021 of DDW and read aloud by Megan Thomas.   The articles are called “Reproducibility in single cell… Read More

#News #Trending News

#AI / data analytics / healthtech / informatics #Bioinformatics #Biopharmaceuticals #Biotechnology #Collaboration

Scitara joins collaboration to drive biopharmaceutical advancements  

Scitara has become a member of BioPhorum, a global community that enables collaboration throughout the biopharmaceutical industry with the goal of accelerating scientific advancements.  The Lab of the Future  Scitara joins BioPhorum Information Technology, which aims to accelerate digital maturity across the global biomanufacturing industry. One of the programmes within the portfolio,… Read More

#News

#Narrated podcasts

What can we learn from the genome?

This is the latest episode of the free narrated DDW podcast, “What can we learn from the genome?”. It covers two narrated articles written for Volume 22, Issue 3 – Summer 2021 of DDW and read aloud by Megan Thomas. The articles are called “Reproducibility in… Read More

#Podcasts

#Drug discovery #Infectious diseases #Molecular Biology #Research

Researchers discover way to disarm potentially deadly Listeria bacteria 

University of Queensland researchers have discovered a way to block Listeria from making the proteins that allow bacteria to survive and multiply in immune cells, which can cause severe illness in pregnant women and people with compromised immune systems. The study has been published in the journal PLOS Pathogens. Read More

#News

#Events #Healthcare

Global Healthcare 2022 conference now available for streaming 

Edison Group’s Edison Open House: Global Healthcare 2022 was a three-day event, in association with London Stock Exchange, global law firm Taylor Wessing and OpenExchange, which took place from January 25-27, focusing on 33 companies. Content is now available to stream.  Streaming   Content is now available… Read More

#News

#Drug discovery

This week in drug discovery (24-28 January) 

News round-up by DDW’s Megan Thomas for 24-28 January, 2022  From further Covid-19 developments to cancer and chronic pain studies, there is a lot to appreciate and get excited about in the drug discovery sector. DDW’s Megan Thomas has rounded up five stories that have stood out… Read More

#News

Knee pain
#Arthritis #Chronic pain #Pharmacology

Altasciences and Virpax conduct first-in-human study of chronic pain

Virpax Pharmaceuticals has chosen Altasciences to conduct a first-in-human study of Epoladerm (diclofenac epolamine) for chronic pain associated with osteoarthritis of the knee. This treatment is supplied in a pre-filled device for administration as a topical spray film.  The study  The study will be conducted in the second quarter of 2022… Read More

#News

#Biopharmaceuticals #Drug discovery #R&D #Therapeutics

Sitting down with… Dr Michael Hayden, Prilenia Therapeutics

Listen to this article on the DDW Podcast: Dr Michael Hayden’s early encounters and experience with patients and families suffering from Huntington’s Disease has had a significant personal impact that shaped his career. As CEO of Prilenia Therapeutics, he tells Lu Rahman why he has dedicated his career… Read More

#Editor's Choice #Exclusive Content #News #Opinion

#Clinical trials #Healthcare #Public health #Training

Psychotherapists begin training for treatment resistant depression trials 

Beckley Psytech has announced that the first cohort of psychotherapists have begun training in advance of the expected Phase II clinical trial examining 5-MeO-DMT-assisted psychotherapy in treatment resistant depression (TRD).   The training  The training is being conducted in collaboration with Fluence, an educational platform that provides professional… Read More

#News

#Events #SLAS2022

SLAS launches SLAS2022 Mobile App  

SLAS has announced that the SLAS2022 Mobile App is ready for download for Apple or Android phone or tablets to access the most up-to-date session information, exhibitor information, participate in the poster scavenger hunt (in-person and virtual), network with attendees, and more.  There is no printed programme at SLAS2022,… Read More

#News

#Biotechnology #Clinical trials #Imaging

Industry predictions for clinical trials 

Medidata reflects on how clinical trials have evolved over the past year, as well as emerging patterns and drivers of change for the coming year. Paul O’Donohoe and Fiona Maini from Medidata explain.  1. The future of clinical trials is decentralised  Decentralised clinical trials, described as… Read More

#Editor's Choice #Exclusive Content #Intelligence #News #Opinion #Trends & Analysis

CRISPR gene editing
#3D modelling #CRISPR #DNA #Drug discovery #Gene editing #Genomics #Screening

CRISPR screening in the third dimension 

Listen to this article on the DDW Podcast: Rosie Bryan & Carlos le Sage, Horizon Discovery, explain how CRISPR-Cas9 technology has become a gold standard for functional genomics.  While efforts in the cancer genomics field have uncovered the mutational landscapes in tumours covering many types of cancer, the… Read More

#Editor's Choice #Exclusive Content #News

Pills
#Approvals #Covid-19 #Marketing approval authorisation

NICE expands guidance for AstraZeneca’s hyperkalaemia drug

The National Institute for Health and Care Excellence (NICE) has updated Technology Appraisal Guidance (TAG) TA599 for AstraZeneca’s Lokelma (sodium zirconium cyclosilicate [SZC]) in the treatment of adult patients with hyperkalaemia in England, Wales, and Northern Ireland.   Context   This guidance update follows the removal of the previous commercial arrangement, meaning… Read More

#News

#Covid booster #Covid variants #Covid-19 #Immunology / Virology & Vaccines #Omicron

Covid-19 booster provides good antibody protection against Omicron 

A third ‘booster’ dose of Covid-19 vaccine successfully raises antibody levels that neutralise the Omicron variant, according to laboratory findings from the Francis Crick Institute and the National Institute for Health Research (NIHR) UCLH Biomedical Research Centre, published as a Research letter in The Lancet.   The results  Researchers found that antibodies generated in people… Read More

#News

Targeting kinases involved in the innate immune response 

Clinical trials continue to determine whether therapeutic modulation of kinases can be used to suppress the immune system in autoimmune diseases or stimulate for antiviral and cancer immunotherapy. The discovery and characterisation of small molecule modulators have aided these efforts.   The Transcreener ADP² Kinase Assay meets this need as it relies… Read More

#Intelligence #Resources