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Biotech company Novavax has announced the initiation of crossover arms in two ongoing clinical trials of NVX-CoV2373, the company’s Covid-19 vaccine candidate. Crossover ensures the administration of active vaccine to all participants in the trials and has begun for Novavax’ Phase IIb trial in South Africa and its pivotal Phase III trial in the UK. […]

A batch of Johnson & Johnson vaccines have been destroyed following a mix up with ingredients at a production site Emergent Biosolutions, in Baltimore. It is thought this could be around 15 million doses, writes the Independent. According to a report in the Guardian, workers at the plant manufacturing coronavirus shots for Johnson & Johnson […]

The Data and Safety Monitoring Board (DSMB) has notified the National Institute of Allergy and Infectious Diseases (NIAID), Biomedical Advanced Research and Development Authority (BARDA), and AstraZeneca that it is “concerned by information released by AstraZeneca on initial data from its COVID-19 vaccine clinical trial”. Trial volunteers received two standard doses of the Oxford-AstraZeneca vaccine […]

A Phase III study of the Oxford-AstraZeneca coronavirus vaccine conducted by AstraZeneca in the US, Chile and Peru has shown that the vaccine is safe and highly effective, adding to previous trial data from the United Kingdom, Brazil and South Africa, as well as real-world impact data from the United Kingdom. In the trial, which recruited over 32,000 volunteers across all age groups, the participants received either […]

The Russian Direct Investment Fund (RDIF) and Stelis Biopharma, the biopharmaceutical division of Strides, a global pharmaceutical company headquartered in India, have partnered to produce and supply a minimum of 200 million doses of the Russian Sputnik V vaccine against COVID-19, sufficient to vaccinate 100 million people. Sputnik V is now approved for use in over 50 countries. […]

Moderna has announced that the first participants have been dosed in the Phase I study of mRNA-1283, the company’s next generation COVID-19 vaccine candidate. mRNA-1283 is being developed as a potential refrigerator stable mRNA vaccine that will facilitate easier distribution and administration by healthcare providers Stéphane Bancel, Chief Executive Officer of Moderna, said: “Our investments […]

‍IRICoR, a pan-Canadian drug discovery and research commercialisation centre, Université de Montréal (UdeM), the Institute for Research in Immunology and Cancer (IRIC) of the Université de Montréal, and Valence Discovery, AI-enabled drug designer, have announced a collaboration focussing on the discovery of novel drug candidates for the treatment of levodopa-induced dyskinesia in Parkinson’s disease. Parkinson’s disease […]

A new report from Invest Stockholm on Advanced Therapeutics Manufacturing and Life Science in the Stockholm region showed that the sector has grown by 66% in the past four years. Collaboration between local tech and pharma industries are expected to further enhance Stockholm’s competitiveness and growth in the future. Both global companies and specialist start-ups […]

Tocilizumab, an anti-inflammatory drug used to treat rheumatoid arthritis, was found to improve outcomes in severely ill COVID-19 patients. These results were found from a new trial conducted in hospitals across India. Researchers from the University of Bristol and Medanta Institute of Education and Research in India who led the study, published in The Lancet […]

IONTAS and FairJourney Biologics (FJB) have entered into an agreement with Quell Therapeutics regarding IONTAS / FJB’s proprietary libraries and technology platforms. A diverse panel of novel target binders from IONTAS and FairJourney Biologics (FJB) will be used to identify antibodies to advance Quell’s engineered Treg cell therapy pipeline. Quell harnesses the suppressive capacity of […]