Resources

Cell and gene therapy infographic
Infographic

Overcome your cell and gene therapy (GMP) challenges

Download this interactive infographic to: Discover ways to navigate your contamination, compliance, reproducibility, monitoring and scalability challenges Identify which critical factors and equipment you should consider to help succeed in a GMP environment Unlock access to an extensive collection of helpful resources

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Whitepaper: Fuelling the future: Precision medicine innovation and the role of ecosystems
Whitepaper

Fuelling the future: Precision medicine innovation and the role of ecosystems

This whitepaper, Fuelling the future: Precision medicine innovation and the role of ecosystems, examines how the future of drug discovery and precision medicine can be enhanced by life science ecosystems such as those created by the UK’s leading property developer to the science and technology sectors, Bruntwood SciTech. In the whitepaper, you will discover: The evolution […]

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Case Study: Improving physiological relevance in neurological disease drug development
Case Study

Improving physiological relevance in neurological disease drug development

In this case study, hear from Elise Malavasi, PhD, a Principal Scientist at leading contract research organisation Concept Life Sciences. The interview highlights their need to develop assays that are amenable to long term use to support their clients with drug development, and how bit.bio’s deterministically programmed ioMicroglia have helped them develop assays with increased […]

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Drug stability testing eBook
eBook

Drug Stability Testing 101

Learn about the key principles, methodologies and regulatory requirements of drug stability testing with our recently developed eBook: ‘Drug Stability Testing 101’. This eBook has been prepared by scientists and industry professionals at Thermo Fisher Scientific to provide you with valuable insights and practical knowledge to help you optimise this critical aspect of pharmaceutical development with […]

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Lonza Biologics white paper
Whitepaper

A comprehensive and flexible approach to CMC for Fab and Fc-fusion development programs

Read this whitepaper to: Gain insights into the diverse and complex structures of new molecular formats, often encompassing multiple chains and multiple domains Understand the unique challenges faced during the process development and manufacture of these advanced proteins Explore how characterising these products and developing robust manufacturing processes can help to usher them to market […]

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Brochure

Multiomics sequencing: How to maximise the data generated from valuable research samples

Understanding the mechanisms of disease requires complex data ranging from genomic data through to transcriptomics, epigenetics and proteomics. Legacy multiomic approaches require multiple platforms and complex processes, which are incompatible with disease research that utilises scarce tissue samples. Download the brochure to learn how multiomic nanopore sequencing can generate data on: Genomics Bulk and single-cell […]

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Case Study

Streamline preclinical drug discovery: PBMC-humanised mouse models

Discover a clinically predictive and reproducible platform developed by The Jackson Laboratory for simultaneous efficacy and safety assessment. This platform identifies patient-therapy combinations at risk of developing severe inflammatory syndrome, a potentially fatal complication. Optimise the safety profiles of your immunomodulatory therapeutics before first-in-human trials by leveraging this platform. In this bispecific case study, learn […]

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App Note

Fcγ Receptor and Antigen Kinetic Screening for Rapid Biosimilar Downstream Processing Assessment

Demonstrating similarity of biomolecules such as antibodies throughout upstream and downstream production processes is crucial. A rapid testing method is demonstrated using a Humira biosimilar (adalimumab) development sample, which assesses compatibility with three essential ligands in compliance with regulatory standards. This Application Note covers: How to rapidly assess column elution fractions of a biosimilar under […]

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App Note

Biologics developability: How Merck creates developability profiles for their mAbs

In this Application Note, discover how the Protein Sciences group at Merck & Co. builds developability profiles for their monoclonal antibody variants. Get an in-depth explanation of the experiments they set up to obtain parameters that help them decide which candidates have the best potential to reach the market, and how they validated that the data they […]

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Whitepaper

Bespoke biosafety: Building a custom biosafety cabinet

Simply having a biosafety cabinet (BSC) with large enough interior dimensions to house automation equipment is not always sufficient for ensuring proper airflow and adequate protection. In many cases, the equipment may actually interfere with the cabinet’s airflow, creating turbulence and rendering the cabinet ineffective. Download this whitepaper about customised biosafety cabinets for robotic equipment […]

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Feature Note

Sustainability in the Lab: A Step-by-Step Guide

Download this guide to gain insights on the steps you can take to achieve a more sustainable lab without compromising quality or performance. Learn about: Conducting an assessment Choosing the right equipment Conserving water and reducing waste Engaging and educating your team

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Whitepaper

Using patient-specific cells for disease modelling

Induced pluripotent stem cell (iPSC)-derived cells are a significant resource for disease modelling. They allow the use of cells directly from affected patients and have the potential to guide these cells towards multiple lineages. Download the whitepaper to: Explore iPSC-derived motor neuron morphology Discover how ALS disease phenotype is observed in microglia phagocytosis Understand whether […]

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Infographic

Four methods for thermal stability assessment of proteins

Thermal stability is among the most common critical quality attributes (CQAs) used for early developability assessment of biologics. In this infographic, learn about four methods for thermal stability assessment of proteins – what they measure, what the data tells you, and their benefits and limitations. While each provides unique value, the table will help you […]

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Case Study

Speeding up neuroscience research: Generating publishable data in 12 weeks

In this Case Study you will learn: How Professor Deepak Srivastava’s lab at King’s College London are working to unpick the complex biology of neuronal synapses to help us better understand neurological disorders like schizophrenia. How the researchers in Professor Srivastava’s lab have been able to generate publishable data on schizophrenia risk factors in just […]

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Guide

HuPK: A Humanised Platform for therapeutic antibody PK evaluation

Download the guide to learn more about:   How JAX’s HuPK™ Humanised FcRn Platform offers a validated and cost-effective solution for assessing the in vivo  preclinical pharmacokinetics and stability of Fc-based biologics and therapeutics carried by albumin.    JAX’s portfolio of FcRn humanised mouse models.   Study design templates, expected results, and troubleshooting tips for the most […]

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eBook

Assessing the efficacy of vaccines through laboratory assays

In the eighth eBook of the Hamilton series, ‘Assessing the Efficacy of Vaccines through Laboratory Assays’, we discuss: Vaccine development: Key milestones and impact of Covid-19 Laboratory tests commonly used to assess vaccines’ efficacy and the benefits of automating them Hamilton standardised and customised solutions for workflows such as qPCR, NGS, ELISA/ELISpot and virus-neutralisation assays

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