Business & Investment

#Alentis Therapeutics #Collaboration #CSL #Phase II trial

CSL and Alentis announce global partnership

CSL and Alentis Therapeutics have entered into an exclusive global collaboration agreement to co-develop and co-promote lixudebart, which has the potential to become a first-in-class therapy targeting claudin-1 across a range of kidney, liver and other diseases.  Under the terms of the agreement, Alentis will receive a… Read More

#Business & Investment #News #Trending News

AI roadmap
#AI / data analytics / healthtech / informatics #Artificial intelligence (AI) #Drug discovery #Investment

AI investment by life science labs hits a four-year high, study finds

The results of a new study show AI/ML investment jumping after three flat years, with three quarters (76%) of respondents planning to increase spending on technology in the next two years, up from 60% in 2023, 62% in 2024, and 63% in 2025.  However, the leading barrier… Read More

#Business & Investment #Editor's Choice #News

#Genentech #License agreement #Neuroscience #Parkinson's

Genentech licenses enzyme replacement therapy for Parkinson’s

Alector has granted Genentech worldwide rights to develop and commercialise its AL050 programme, a brain-penetrant engineered glucocerebrosidase (GCase) enzyme replacement therapy (ERT).  As part of the deal, Alector will receive a $100 million upfront payment, with potential for up to $1.17 billion in additional milestone payments, as… Read More

#Business & Investment #News

Deal making
#Mergers and acquisitions #Neurodegenerative disorders #Rare disease #Shionogi

Shionogi expands rare disease portfolio with IntraBio buyout

Shionogi has announced plans to acquire IntraBio, a biopharmaceutical company developing therapies for neurodegenerative diseases, for $2 billion.  The transaction will add Aqneursa (levacetylleucine) and IntraBio’s capabilities in the rare disease area to Shionogi’s growing portfolio.  Aqneursa was approved by the FDA in September 2024… Read More

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Protein degrader
#Collaboration #Eli Lilly #Gate Bioscience #Protein degradation

Lilly and Gate agree $870m deal for molecular gate medicines

Eli Lilly and Gate Bioscience have expanded their collaboration to discover, develop, and commercialise molecular gate therapeutics.   The expanded collaboration adds one target, with the opportunity to add a second target, to the companies’ existing work.   The programmes leverage Gate’s Molecular Gate drug discovery engine… Read More

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Downing Street, London, UK
#Association of the British Pharmaceutical Industry #BioIndustry Association #UK economy

UK groups call on government to back life sciences ambitions in the Budget

Ahead of the Budget, UK life sciences groups have called on the Chancellor to prioritise investment in new medicines.  The UK government has set out bold targets for the UK’s life sciences sector. By 2030, it wants the UK to lead Europe in commercial research and development… Read More

#Business & Investment #News #Trending News

#Europe #Investment #Market reporting #Survey

European biopharma investment confidence increasing, c-suite survey reveals

Biopharma dealmaking confidence is strengthening, a new survey has revealed, but access to capital remains the defining challenge.  BIO-Europe’s Biopharma C-Suite Agenda Survey 2026 surveyed 81 senior biopharma executives, including 50 CEOs.  The survey results demonstrate that 75% expect partnering and M&A appetite to increase… Read More

#Business & Investment #Editor's Choice #News

Dollar sign on a tablet
#Collaboration #KRAS #MSD #Oncology #SciBrunch Therapeutics

MSD buys oral KRAS G12D (ON) inhibitor for $2.13 billion

SciBrunch Therapeutics and MSD (or Merck & Co) have entered into an exclusive global license agreement for SPR2015, an investigational preclinical oral KRAS G12D (ON) inhibitor.  Under the agreement, SciBrunch has granted MSD exclusive rights to develop, manufacture and commercialise SPR2015 worldwide.   SciBrunch will receive… Read More

#Business & Investment #News

University of Melbourne
#Financing #Radiopharmaceuticals #Spinout #Start-ups #University of Melbourne

Melbourne radiopharmaceuticals spinout launches with AUD$12 million

Australian radiopharmaceuticals spinout, Skopos Bio, has launched with an AUD$12 million (US$8.3 million) seed round, led by a global investor syndicate.  The company was founded by three clinical and translational scientists from Melbourne’s Peter MacCallum Cancer Centre (Peter Mac), who continue to treat patients and lead research:… Read More

#Business & Investment #News #Start-up Zone

Structure of the eye
#Breye Therapeutics #Financing #Ophthalmology #Retinal diseases

Breye raises €67.5 million for retinal disease therapies

Breye Therapeutics has closed an over-subscribed €67.5 million Series A financing round.   The round was co-led by new investor Mission BioCapital and existing investor Novo Holdings, with participation from existing investor Sound Bioventures and additional new investors including the Ljungström family office, Innovestor Life Science, EIFO, Catalyze… Read More

#Business & Investment #News

Red blood cells
#Collaboration #Defense Advanced Research Projects Agency (DARPA) #Metabolic diseases #Scarlet Therapeutics

Scarlet secures $14m DARPA deal for smart red blood cells

Scarlet Therapeutics has entered into an agreement with the Defense Advanced Research Projects Agency (DARPA) to advance the development of smart red blood cells (SRBCs).   Scarlet will lead a multidisciplinary consortium to develop SRBCs in a programme worth up to $14 million.  The agreement builds… Read More

#Business & Investment #News

Europe
#Europe #Investment #Pharmaceutical industry

Pharma urges leaders to reverse Europe’s declining competitiveness

An open letter from the chairs of AstraZeneca, Boehringer Ingelheim, Chiesi Group, Ipsen, GSK, Novo, Novartis, Roche, and Sanofi has urged European governments to create conditions that attract investment in next-generation medicines.  They argue that Europe is losing ground to global competition, with over $600 billion in… Read More

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#Collaboration #Drug delivery #Nanexa #Novo Nordisk #Peptides

Novo and Nanexa agree €1.165 billion drug delivery deal

A new agreement grants Novo a global exclusive license to Nanexa’s PharmaShell atomic layer deposition (ALD) drug delivery technology platform for certain therapeutic peptide drugs in indications including obesity, type 2 diabetes and other cardiometabolic diseases.  The collaboration includes development of long-acting injectable formulations with different administration-frequency… Read More

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Neuroscience Parkinson's disease
#Ariadne Bio #Neurodegenerative disorders #Neuroscience #Parkinson's #Spinout #Start-ups

Ariadne Bio spins out to target apathy in Parkinson’s disease

Palomar Labs (formerly Negev Labs), a venture studio that builds companies around neuropsychiatric drug development programmes with prior human validation, has announced the spinout of Ariadne Bio, its first portfolio company.   Ariadne Bio launches with lead programme AB-300, a clinical-stage-ready, non-hallucinogenic serotonin 2A receptor agonist in development… Read More

#Business & Investment #News #Start-up Zone

Novo Nordisk head office
#Anthropic #Artificial intelligence (AI) #Cardiometabolic diseases #Collaboration #Novo Nordisk

New deals boost Novo Nordisk’s AI drug discovery ambitions

Novo Nordisk and Orbis Medicines have announced a strategic collaboration and license agreement to discover and develop oral macrocycle therapeutics for cardiometabolic diseases.   Under the terms of the agreement, Orbis Medicines is eligible to receive up to $1.4 billion in upfront and potential development and commercial milestone… Read More

#Business & Investment #News