By Dr J. Mark Treherne, et al.,

Will the automated expansion of organoids help improve the productivity of cancer drug discovery?

By Helen Stewart-Miller and Dr Richard Massey

Once the domain of high-throughput screening (HTS) applications, automated liquid handling systems are now used ubiquitously in drug discovery and ...

By Dr Richard M. Eglen, Dr Feng Li and Dr Tony Frutos

Drug candidates often fail in the clinic for two reasons: they lack efficacy or possess an adverse toxicity profile. These failures can come at a h...

By Dr Kirkwood A. Pritchard Jr, Dr Dustin P. Martin and Dr Stephen Naylor

The safety and efficacy of therapeutic drugs still requires improvement. In part this is due to the promiscuity of individual drugs, which on avera...

By Dr Patrick Guye, Dr Eva Thoma and Dr Olivier Frey

Life operates in three spatial dimensions (3D), as do the patients for whom we are developing therapies and cures. Earlier limitations in cell cult...

By Dr Mahmoud Ameri and Hayley Lewis

Oral drug delivery is the most common and convenient route of drug administration due to a high rate of patient compliance, cost-effectiveness, por...

By Katherine Briggs, et al.,

The Pistoia Alliance, brought together a crossfunctional life science industry group to review common challenges and opportunities in non-clinical ...

By Scott Hickman, Dr Brian Ogilvie and Tim Patterson

Good Laboratory Practices (GLP) are federal regulations that require implementation of a robust quality management system to ensure the validity, i...