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Latest Issue - Winter 2018/19

The Growth of Organoids in Cancer Drug Discovery

By Dr J. Mark Treherne, et al.,

Will the automated expansion of organoids help improve the productivity of cancer drug discovery?

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How advanced automated liquid handling systems are reshaping drug discovery

By Helen Stewart-Miller and Dr Richard Massey

Once the domain of high-throughput screening (HTS) applications, automated liquid handling systems are now used ubiquitously in drug discovery and ...

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Optimising Clinical Leads: Increasing drug discovery success with 3D cell culture systems

By Dr Richard M. Eglen, Dr Feng Li and Dr Tony Frutos

Drug candidates often fail in the clinic for two reasons: they lack efficacy or possess an adverse toxicity profile. These failures can come at a h...

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Perspective on Systems Pharmacology: When multi-targeting is advantageous

By Dr Kirkwood A. Pritchard Jr, Dr Dustin P. Martin and Dr Stephen Naylor

The safety and efficacy of therapeutic drugs still requires improvement. In part this is due to the promiscuity of individual drugs, which on avera...

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Considerations for engineering composable, disease-tunable 3D human microtissues

By Dr Patrick Guye, Dr Eva Thoma and Dr Olivier Frey

Life operates in three spatial dimensions (3D), as do the patients for whom we are developing therapies and cures. Earlier limitations in cell cult...

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The Evolution of Transdermal Drug Delivery and Treating Migraine

By Dr Mahmoud Ameri and Hayley Lewis

Oral drug delivery is the most common and convenient route of drug administration due to a high rate of patient compliance, cost-effectiveness, por...

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Beyond SEND: Leveraging non-clinical data to drive translational research forward

By Katherine Briggs, et al.,

The Pistoia Alliance, brought together a crossfunctional life science industry group to review common challenges and opportunities in non-clinical ...

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To GLP or not to GLP? That is the question...

By Scott Hickman, Dr Brian Ogilvie and Tim Patterson

Good Laboratory Practices (GLP) are federal regulations that require implementation of a robust quality management system to ensure the validity, i...

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Product & Industry News

Lonza Expands Mycoplasma Detection Portfolio

 

Lonza Expands Mycoplasma Detection Portfolio with New Luminometer Designed to Accelerate and Simplify Testing

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Issuance of University of California CRISPR/Cas9 patent

 

ERS Genomics provides comment on issuance of University of California CRISPR/Cas9 patent including uses of CRISPR ‘in a cell’

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REPROCELL join Medicines Discovery Catapult’s Virtual R&D network to accelerate drug development

 

REPROCELL will provide custom drug discovery assays using live human tissues to improve the prediction of drug safety and efficacy. The collaborati...

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FUJIFILM Irvine Scientific Introduces Low Hydrolysate Medium For Insect Cell Expression Systems

 

FUJIFILM Irvine Scientific, Inc., a world leader in the optimization and manufacture of cell culture media, today announced the introduction of IS ...

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Envigo launches PATHWAY, optimized safety assessment solution

 

Envigo launches PATHWAY, an optimized safety assessment solution to enable first-in-human clinical trials

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Repositive to demonstrate Cancer Models Scout at AACR 2019

 

Repositive to demonstrate how its Cancer Models Scout service can connect biopharmas with the right preclinical cancer models via an interactive ap...

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