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Latest Issue - Winter 2018/19

The Growth of Organoids in Cancer Drug Discovery

By Dr J. Mark Treherne, et al.,

Will the automated expansion of organoids help improve the productivity of cancer drug discovery?

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How advanced automated liquid handling systems are reshaping drug discovery

By Helen Stewart-Miller and Dr Richard Massey

Once the domain of high-throughput screening (HTS) applications, automated liquid handling systems are now used ubiquitously in drug discovery and ...

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Optimising Clinical Leads: Increasing drug discovery success with 3D cell culture systems

By Dr Richard M. Eglen, Dr Feng Li and Dr Tony Frutos

Drug candidates often fail in the clinic for two reasons: they lack efficacy or possess an adverse toxicity profile. These failures can come at a h...

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Perspective on Systems Pharmacology: When multi-targeting is advantageous

By Dr Kirkwood A. Pritchard Jr, Dr Dustin P. Martin and Dr Stephen Naylor

The safety and efficacy of therapeutic drugs still requires improvement. In part this is due to the promiscuity of individual drugs, which on avera...

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Considerations for engineering composable, disease-tunable 3D human microtissues

By Dr Patrick Guye, Dr Eva Thoma and Dr Olivier Frey

Life operates in three spatial dimensions (3D), as do the patients for whom we are developing therapies and cures. Earlier limitations in cell cult...

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The Evolution of Transdermal Drug Delivery and Treating Migraine

By Dr Mahmoud Ameri and Hayley Lewis

Oral drug delivery is the most common and convenient route of drug administration due to a high rate of patient compliance, cost-effectiveness, por...

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Beyond SEND: Leveraging non-clinical data to drive translational research forward

By Katherine Briggs, et al.,

The Pistoia Alliance, brought together a crossfunctional life science industry group to review common challenges and opportunities in non-clinical ...

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To GLP or not to GLP? That is the question...

By Scott Hickman, Dr Brian Ogilvie and Tim Patterson

Good Laboratory Practices (GLP) are federal regulations that require implementation of a robust quality management system to ensure the validity, i...

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Product & Industry News

Bio-Rad Showcases New Automation Features of its ZE5 Cell Analyzer at SLAS 2019

 

Automation-Ready Flow Cytometer Enables Biomarker Discovery and Phenotypic Screening

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Chemspace and LabNetwork collaborate to extend access to chemical databases

 

Collaboration provides drug discovery researchers access to European distribution and local support for library of in-stock and on-demand compounds

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Lonza's New Pooled Donor Suspension Hepatocytes

 

Lonza’s New Pooled Donor Suspension Hepatocytes Enable the Next Level of Reliability, Robustness and Customizability

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Bio-Rad Introduces Anti-Eculizumab Antibodies

 

Bio-Rad Laboratories, Inc., have announced the launch of a range of recombinant monoclonal anti-idiotypic antibodies that inhibit the binding of ec...

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Tecan launches NGS DreamPrep

 

Tecan launches NGS DreamPrep delivering unprecedented speed and accuracy for automated library preparation

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Moderna exercises option for an exclusive product license with Avacta Group plc

 

Avacta Group plc, the developer of Affimer biotherapeutics and reagents, is pleased to announce that ModernaTX, Inc. has exercised its option to en...

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