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Latest Issue - Winter 2018/19

The Growth of Organoids in Cancer Drug Discovery

By Dr J. Mark Treherne, et al.,

Will the automated expansion of organoids help improve the productivity of cancer drug discovery?

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How advanced automated liquid handling systems are reshaping drug discovery

By Helen Stewart-Miller and Dr Richard Massey

Once the domain of high-throughput screening (HTS) applications, automated liquid handling systems are now used ubiquitously in drug discovery and ...

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Optimising Clinical Leads: Increasing drug discovery success with 3D cell culture systems

By Dr Richard M. Eglen, Dr Feng Li and Dr Tony Frutos

Drug candidates often fail in the clinic for two reasons: they lack efficacy or possess an adverse toxicity profile. These failures can come at a h...

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Perspective on Systems Pharmacology: When multi-targeting is advantageous

By Dr Kirkwood A. Pritchard Jr, Dr Dustin P. Martin and Dr Stephen Naylor

The safety and efficacy of therapeutic drugs still requires improvement. In part this is due to the promiscuity of individual drugs, which on avera...

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Considerations for engineering composable, disease-tunable 3D human microtissues

By Dr Patrick Guye, Dr Eva Thoma and Dr Olivier Frey

Life operates in three spatial dimensions (3D), as do the patients for whom we are developing therapies and cures. Earlier limitations in cell cult...

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The Evolution of Transdermal Drug Delivery and Treating Migraine

By Dr Mahmoud Ameri and Hayley Lewis

Oral drug delivery is the most common and convenient route of drug administration due to a high rate of patient compliance, cost-effectiveness, por...

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Beyond SEND: Leveraging non-clinical data to drive translational research forward

By Katherine Briggs, et al.,

The Pistoia Alliance, brought together a crossfunctional life science industry group to review common challenges and opportunities in non-clinical ...

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To GLP or not to GLP? That is the question...

By Scott Hickman, Dr Brian Ogilvie and Tim Patterson

Good Laboratory Practices (GLP) are federal regulations that require implementation of a robust quality management system to ensure the validity, i...

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Product & Industry News

TC BioPharm initiates Phase I trial of allogeneic gamma delta T cell therapy

 

TC BioPharm initiates Phase I trial of allogeneic gamma delta T cell therapy in Acute Myeloid Leukemia patients

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US Patent Office Grants Charpentier/Doudna Key CRISPR Patent

 

US patent number 10,266,850 was previously involved in an interference proceeding.

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Surge of Indian biosimilars market forecast in 2019

 

CPhI data predicts India to be one of the world’s ‘fastest growing bio’ hubs in 2019, fuelled by new biosimilars production

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Taconic Biosciences Launches TruBIOME

 

Taconic Biosciences Launches TruBIOME to Create Animal Models with Custom Microbiome Profiles

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My Personal Therapeutics Announces Funding & Secures Exclusive Mount Sinai License

 

My Personal Therapeutics Announces Funding and Secures Exclusive Mount Sinai School of Medicine Technology License to Revolutionize Personalized Ca...

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Bio-Rad Introduces Isotype-Specific Secondary Antibodies

 

Bio-Rad Laboratories, Inc., a global leader of life science research and clinical diagnostic products, today announced the launch of its isotype-sp...

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