Cancer Research

Study highlights real-world impact of AI platform in precision medicine 

21 October 2021

Exscientia, the Medical University of Vienna and the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences has published final results from the EXALT-1 trial in Cancer Discovery.  The study, titled “Functional Precision Medicine Provides Clinical Benefit in Advanced Aggressive Haematological Cancers and Identifies Exceptional Responders,” illustrates the potential real-world impact of using Exscientia’s AI-supported precision medicine platform (referred to in […]

‘Gut bugs’ can drive prostate cancer growth and treatment resistance 

14 October 2021

Scientists revealed in a new study how gut bacteria contribute to the progression of advanced prostate cancers and their resistance to hormone therapy by providing an alternative source of growth-promoting androgens, or male hormones.  Hormone therapy is the standard of care for advanced prostate cancer and works by lowering levels of androgens. But researchers found […]

New cancer ‘inhibitor’ could lead to improved treatment options

30 September 2021

Researchers have discovered a potential advancement in the treatment of chronic myeloid leukaemia (CML), which they hope will one day offer an improved option for treating patients with this form of blood cancer. The study– published in Science Translational Medicine and led by the University of Glasgow in collaboration with LifeArc – has discovered a […]

Cancer Awareness Month: Round up 

30 September 2021

September 2021 has been Cancer Awareness Month for Blood, Childhood, Gynaecologic, Ovarian and Prostate Cancer, which affect millions of people around the world annually. Here is a round-up of eight of some of the innovative research and studies being done in order to tackle these various types of cancer.   1. Building a pipeline of clinically-differentiated cancer therapies  Avacta Group […]

Proteogenomics study suggests treatment for pancreatic cancer 

28 September 2021

A large, international collaboration led by researchers from the Johns Hopkins Kimmel Cancer Center has identified promising new targets for pancreatic cancer treatment and early diagnosis after examining various aspects of these tumours’ genes and proteins.  “Right now, patients with pancreatic cancer have very few options, and the wealth of data produced by this study could lead […]

Promise in treatment-resistant advanced ovarian cancer 

24 September 2021

A new combination of targeted drugs for a type of ovarian cancer has shown promising results in an early clinical trial, shrinking tumours in half of patients. The combination of drugs, which both work by blocking signals cancer cells need to grow, could offer a new treatment option for women with an uncommon type of ovarian cancer […]

Cancer Research UK and University of Edinburgh start-up boost 

23 September 2021

A University of Edinburgh business-support programme has partnered with Cancer Research UK to help build startup companies focused on tackling cancer.  The charity will fund up to ten participants in the second round of the university’s Data-Driven Entrepreneurship (DDE) Venture Builder Incubator, which supports postgraduate students, postdoctoral researchers and academic staff to develop their startup ideas for three months. […]

Scientists identify new therapeutic target in ovarian cancer subtype

22 September 2021

Mutations in the ARID1A gene are present in more than 50% of ovarian clear cell carcinomas (OCCC), for which effective treatments are lacking. Scientists at The Wistar Institute discovered that loss of ARID1A function enhances a cellular stress response pathway that promotes survival of cancer cells, which become sensitive to pharmacological inhibition of this pathway.   […]

Can Covid-19 vaccine technology be used for cancer vaccines?

22 September 2021

Scientists from the University of Oxford and the Ludwig Institute for Cancer Research are building on the Oxford-AstraZeneca vaccine for SARS-CoV-2 to develop a vaccine to treat cancer.   Researchers have designed a two-dose therapeutic cancer vaccine using Oxford’s viral vector vaccine technology. When tested in mouse tumour models, the cancer vaccine increased the levels of anti-tumour T cells […]

CPRIT grant awarded to test potential large-molecule cancer drugs  

21 September 2021

Qingyun Liu, leader of a preclinical development core where researchers can test the effectiveness of large molecule drug candidates for novel cancer treatments, has been awarded an approximately $4 million grant from the Cancer Prevention and Research Institute of Texas (CPRIT).  Liu is Professor of Precision Biomedicine with the Brown Foundation Institute of Molecular Medicine for […]

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