Discover how process optimisation utilising automated synthetic biology solutions can remove the antibody sequence cloning bottleneck that divides high-content lead identification and downstream high throughput characterisation. If your work involves antibody discovery or process improvement in recombinant cloning don’t miss this whitepaper illustrating how Codex DNA’s synthetic biology solutions can… Read More
Since the turn of the century, when the term “personalised medicine” was first coined, the use of molecular diagnostic (or biomarker) testing in clinical trials has continued to grow in terms of complexity and importance. These tests have undergone a period of rapid development and growth in the last decade, with the implementation… Read More
New UCLA-led research in mice suggests that adding a certain type of tomato concentrate to the diet can reduce the intestinal inflammation that is associated with HIV. Left untreated, intestinal inflammation can accelerate arterial disease, which in turn can lead to heart attack and stroke. The study is published… Read More
Results of a new study by researchers at Case Western Reserve University represent a step toward improving understanding of Crohn’s disease and the factors that cause its intestinal inflammation. About Crohn’s disease Crohn’s disease is a type of inflammatory bowel disease that can lead… Read More
Revelar Biotherapeutics and Twist Bioscience have announced that RBT-0813 binds to and neutralises the Omicron and Delta variants of SARS-CoV-2 in live virus studies. What is RBT-0813? RBT-0813 is a bispecific antibody discovered by Twist Biopharma and licensed to Revelar Biotherapeutics that targets epitopes on the SARS-CoV-2 spike protein. Revelar has continued… Read More
PhoreMost, a UK-based biopharmaceutical company developing drugs against intractable disease targets, and Polaris Quantum Biotech (POLARISqb), a NC-based quantum computing drug design company, have collaborated to study oncology targets currently considered undruggable. The agreement The POLARISqb Tachyon quantum computing platform will be used to scan billions of… Read More
A study from researchers in the Perelman School of Medicine at the University of Pennsylvania has shown that an experimental immunotherapy can temporarily reprogramme patients’ immune cells to attack a specific target via only a single injection of mRNA, similar to the mRNA-based Covid-19 vaccines. Context The researchers, whose… Read More
Sanofi and Exscientia have announced a research collaboration and license agreement to develop up to 15 novel small molecule candidates across oncology and immunology, leveraging Exscientia’s end-to-end AI-driven platform utilising actual patient samples. Background The companies have been working together since 2016 and in 2019, Sanofi in-licensed Exscientia’s novel bispecific small… Read More
Drug Discovery World is the global voice for the drug discovery community. From research stage to clinical trials the brand covers the scientific and commercial process involved in getting a drug to market – research, target identification and validation, drug molecule identification, lead molecule optimisation, pre-clinical research, clinical… Read More
News round-up by DDW’s Megan Thomas for 3-7 January, 2022 With the new year comes new discoveries, results, research, data and collaboration in the drug discovery industry. This week, DDW’s Megan Thomas has selected her top five news stories which have emerged in the sector. … Read More
Pharmaceutical companies must keep improving Covid-19 treatments in line with new variants without sidelining work in other areas of health, according to new data from YouGov and Informa Pharma Intelligence, a provider for the biopharma industry. The report This data, included in Informa Pharma’s ‘Q4… Read More
Scientists at La Jolla Institute for Immunology (LJI) and Charles River Laboratories International are launching a new project to uncover how different cells in the human immune system respond to SARS-CoV-2, the virus that causes Covid-19. The research This new mouse model has been engineered… Read More
Pfizer and BioNTech have announced a new research, development and commercialisation collaboration to develop a potential first mRNA-based vaccine for the prevention of shingles (herpes zoster virus, or HZV), which impacts about one in three people in the US during their lifetime. Why now? The collaboration… Read More
Altasciences, an integrated CRO/CDMO offering solutions to early-stage drug development, has completed the acquisition of Sinclair Research, a preclinical CRO located in the Midwest (US). The new site will facilitate access to Altasciences’ preclinical services across the US. “This acquisition will add significant capacity and expertise to Altasciences’ existing… Read More
Not only is there is a severe lack of effective T-cell lymphoma (TCL) treatments, according to GlobalData, but the data and analytics company does not expect any significant solutions to appear in the next decade. Context According to GlobalData, one key unmet need is found in the… Read More
The first results of an early trial of a multivariant Covid-19 vaccine booster, launched in Manchester in September 2021, has shown it is driving a comprehensive immune response. The results US-based biotechnology company Gritstone bio, in collaboration with The University of Manchester and Manchester University… Read More
