Author Archives: Megan Thomas

#Biotechnology #Biotherapeutics

Nuclera announces expansion with new US subsidiary 

Nuclera, a UK-based biotech company, has opened a US subsidiary located in Boston, MA. This is designed to push Nuclera’s eProtein desktop bioprinter for biotherapeutics.  Dr Michael Chen, CEO and cofounder of Nuclera, said: “This site opening just outside one of the most important biotech markets is a big step towards Nuclera’s goal… Read More

#News

#Biotechnology #Lab automation

A new era for automated liquid handling 

Laboratories across the biotech and pharmaceutical industries are increasingly automating their liquid handling and dispensing capabilities with versatile, scalable, and affordable instruments that cater to a range of applications. This paid-for advertorial by SPT Labtech appeared in the DDW / SLAS supplement in DDW Volume 23, Issue 1 –… Read More

#Exclusive Content #News #Sponsored Content

#Biotechnology #Drug discovery #Therapeutics

Drug discovery movers: who’s going where? 

The new year is underway and with it comes a raft of movement within some of the industry’s key businesses. DDW’s Megan Thomas rounds up seven new additions to the sector.  Dr Charles Woler (Sygnature Discovery, UK)  Sygnature Discovery, provider of drug discovery solutions, has appointed Dr Charles Woler as Chairman. Dr Woler has… Read More

#News #Trending News

#Collaboration #Drug candidates #Drug discovery

Drug discovery collaboration tackles metabolic diseases

Evotec has entered into a drug discovery collaboration with Eli Lilly and Company (Lilly) in the field of metabolic diseases with a focus on kidney diseases and diabetes.  The collaboration  The collaboration leverages Evotec’s metabolic disease experience, as well as its kidney disease patient database,… Read More

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#Biotechnology #Clinical trials #Drug development #Tumours

Avacta takes step to increase the tolerability of chemotherapies  

Avacta has added the next pre|CISION drug candidate to its portfolio. AVA3996, has been selected for pre-clinical development with a view to a first-in-human Phase I clinical trial beginning in the second half of 2023.  The technology  Avacta’s chemistry is used to modify chemotherapy drugs to render them inactive… Read More

#News

Human eye
#Clinical trials #Comment #Covid-19 #Eye health

Innovative delivery: sustained ophthalmic steroids in diabetic macular edema 

Listen to this article on the DDW Podcast: Professor Sobha Sivaprasad, Professor of Retinal Clinical Studies, UCL Institute of Ophthalmology, and Consultant Ophthalmologist, Moorfields Eye Hospital, UK discusses unmet needs in DME therapeutics and how they could be addressed by sustained release ophthalmic steroids administered with novel suprachoroidal drug… Read More

#Editor's Choice #Exclusive Content #News #Opinion #Trends & Analysis

#AstraZeneca #Biobanking #Genetics #Genomics

Rare variant contribution to human disease  

Listen to this article on the DDW Podcast: Slavé Petrovski and Andrew Harper, Centre for Genomics Research, AstraZeneca, outline the implications and insight offered by the recent publication of an AstraZeneca-authored paper “Rare variant contribution to human disease in 281,104 UK Biobank exomes”.  In August 2021, Nature published… Read More

#Exclusive Content #News #Opinion #Trends & Analysis

#Biotechnology #CRISPR #Life sciences #Microfluidics

Advances in automated genome engineering 

Olivia Hughes from Sphere Fluidics discusses how advances in picodroplet microfluidics, combined with the high efficiency of CRISPR/Cas9 technology, are fuelling a new wave of innovation in the form of a simple click-through workflow for genome editing.  Picodroplet microfluidics is rapidly becoming the technology of choice for high-throughput single cell analysis, providing an… Read More

#Editor's Choice #Exclusive Content #News #Opinion

#Alzheimer's #Events #Neuroscience

AlzeCure gets late-breaking neuroscience abstract accepted  

AlzeCure Pharma, a pharmaceutical company that develops small molecule candidate drugs for diseases affecting the central nervous system, has announced that an abstract on clinical data of its candidate drug ACD856 has been accepted for a poster presentation at AD/PD 2022, which this year will be held in Barcelona on… Read More

#News

#Antibodies #Autoimmune disease #Clinical trials #Therapeutics

eBook: Antibody production

In immunoassays-based research, immunodiagnostics, as well as immunotherapy, one of the highly critical aspect of antibodies is their reproducible performance. Antibody reproducibility is driven by their specificity and several other factors ranging from antibody design to target validation. This NEW eBook Antibody Production gives you an overview of the… Read More

#News

Antibody Production

In immunoassays-based research, immunodiagnostics, as well as immunotherapy, one of the highly critical aspect of antibodies is their reproducible performance. Antibody reproducibility is driven by their specificity and several other factors ranging from antibody design to target validation. This NEW eBook Antibody Production gives you an overview of the antibody’s life cycle… Read More

#Intelligence #Resources

#AI #Drug delivery #Life sciences #Machine learning

Replatforming R&D with the TetraScience R&D data cloud 

TetraScience resolves root cause scientific data problems with a cloud-native platform, purpose-built to benefit scientists and data scientists, who use Tetra Data for automation and ML/AI. This paid-for advertorial by TetraScience appeared in the DDW / SLAS supplement in DDW Volume 23, Issue 1 – Winter 2021/22  Technology drives the… Read More

#Exclusive Content #Sponsored Content

Lung cancer
#AstraZeneca #Lung cancer #Oncology

Success for AstraZeneca lung cancer therapy 

AstraZeneca’s Tagrisso (osimertinib) has been accepted for use within NHS Scotland by the Scottish Medicines Consortium (SMC) as monotherapy for the first-line treatment of adult patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) with activating epidermal growth factor receptor (EGFR) mutations.1  Context  Lung… Read More

#News #Trending News

#AI / data analytics / healthtech / informatics #Comment #Drug discovery #SLAS2022

Comment: AI-powered drug discovery 

The Winter issue of the Drug Discovery World Magazine is accompanied by an exclusive DDW & SLAS2022 supplement ahead of SLAS2022 in Boston, US on 5-9 February. As we all look forward to the expertise at the event, DDW’s Megan Thomas outlines the highlights of the first SLAS 2021 AI-Powered Drug Discovery… Read More

#Editor's Choice #Exclusive Content #News #Opinion

#Cell and gene therapy #Funding

Ori Biotech raises over $100 million to launch CGT platform 

Ori Biotech, a producer of cell and gene therapy (CGT) manufacturing technology, has secured over $100 million in an oversubscribed Series B funding round and will use the funds to further expand key personnel across all functions, in order to rapidly transition through pre-commercialisation to the launch of its CGT manufacturing platform. … Read More

#News