Assessing the safety and efficacy of biotherapeutics is imperative during the drug-development process. In particular, pharmacokinetic (PK) and anti-drug antibody (ADA) assays are conducted to study and evaluate new drug candidates and biosimilars. For PK/ADA assays, anti-idiotype antibodies (Anti-IDs) are powerful tools to measure the concentration of antibody drugs in… Read More
The US Food and Drug Administration (FDA) has approved the Biologics License Application (BLA) for Moderna’s Spikevax, an mRNA vaccine for prevention of Covid-19 in individuals 18 years of age and older. Official comments “Our Covid-19 vaccine has been administered to hundreds of millions of… Read More
IAVI and Moderna have announced that first doses have been administered in a clinical trial of experimental HIV vaccine antigens at George Washington University (GWU) School of Medicine and Health Sciences in Washington, DC. The trial The Phase I trial, IAVI G002, is designed to… Read More
Metabolon has collaborated with the FinnGen study in Finland to provide metabolomics data for population health studies to improve understanding of human health. Why collaborate? FinnGen will incorporate deep metabolomic datasets to better understand how genetic drivers of disease may impact biological function and influence… Read More
A number of new sickle cell disease (SCD) drugs are set to hit the US market, says GlobalData, including gene therapies that could offer patients a cure. The cause of the increase GlobalData notes that one of the gene therapies that is currently closest to… Read More
During The Clear Case for Diversity, Equity and Inclusion in Life Sciences, an event at SLAS2022, SLAS CEO Vicki Loise announced a new scholarship aimed at increasing the diversity of the STEM workforce, in partnership with the National Organization for the Professional Advancement of Black Chemists… Read More
Phesi has released the results of its global analysis of all clinical trials conducted in 2021, which shows that breast cancer was the most studied disease area, followed by Covid-19. Overall, oncology dominated the top five, which also included non-small cell lung cancer, solid tumours and multiple myeloma (Figure… Read More
Evonetix is reimagining biology. Dr Vijay Narayan, Head of Physics, Dr Stuart Crosby, Head of Synthetic Chemistry, and Daniel Bygrave, Principal Software Engineer, offer insight into the technology being developed by the company and its relevance for researchers. “I have always been intrigued by interdisciplinary environments,’… Read More
News round-up by DDW’s Megan Thomas for 7-11 February, 2022 This week has proved eventful in terms of progression in the drug discovery industry. DDW’s Megan Thomas flags five news stories which display this. 1. Additional dose of Covid-19 vaccine is safe, says US trial … Read More
“The message was clear from industry leaders this year whether on social media or conferences: today’s clinical trials need decentralised solutions”, says Temitope Keyes, Executive Director Business Development at encapsia, commenting on the decentralised clinical trial (DCT) event horizon. Clinical trials are now more complex… Read More
Protas, a non-profit organisation which was launched on January 24, will design and deliver large, inclusive, randomised clinical trials, working in collaboration with industry partners, medical charities, patient groups, academic researchers, and frontline clinical teams. Sanofi is its first strategic partner. Outlook By combining randomised trial design with effective technology and a collaborative… Read More
FRAME, a medical research charity that aims to reduce the number of animals used in scientific testing, has awarded a total of £29,000 to three projects with the potential to replace animal use in biomedical research. The award FRAME’s innovation grant funding stream is designed… Read More
This 28-page DDW eBook, sponsored by Bio-Rad, contains exclusive insight from industry experts on what’s new in lab automation and how this technology can accelerate your drug discovery process and is available to download now. With this guide, you can learn more about: The benefits of automation and how to… Read More
This 28-page DDW eBook, sponsored by Bio-Rad, contains exclusive insight from industry experts on what’s new in lab automation and how this technology can accelerate your drug discovery process. Download this guide to learn more about: The benefits of automation and how to take the first steps How trends such… Read More
Listen to this article on the DDW Podcast: The Winter issue of the Drug Discovery World Magazine is accompanied by an exclusive DDW & SLAS2022 supplement… Read More
Moderna has dosed the first participant in a Phase II study of the company’s Omicron-specific booster candidate (mRNA-1273.529). Additionally, Moderna announced the publication of neutralising antibody data against the Omicron variant six months following a booster dose in The New England Journal of Medicine. The mRNA-1273.529 trial This extension… Read More
