Human Cell Design, a biotechnology company focused on generating translational human cellular models, has launched Endoc-BH5 to “open up entirely new scientific avenues in diabetes studies”, the company says. What is Endoc-BH5? Human Cell Design combined hiPSC-derived differentiated cells (human-induced Pluripotent Stem Cells) and primary… Read More
Sonia Marsilio is an Associate Product Manager at Enzo. She explains how research tools enable scientists to accelerate immunotherapy. The growing, continuously evolving arsenal of cancer immunotherapies has changed the treatment landscape of many tumours. Dominating the space are the CAR T cell therapies, with CD19, BCMA, and CD22… Read More
The latest episode of the free DDW podcast is titled“What do we know about lab automation?”. It covers two narrated articles written for Volume 22, Issue 3 – Summer 2021 of DDW, read by Megan Thomas. The articles are “What has 2020 taught us… Read More
The latest episode of the free narrated DDW podcast is titled “What do we know about lab automation?”. It covers two narrated articles written for Volume 22, Issue 3 – Summer 2021 of DDW, read by Megan Thomas. The articles are “What… Read More
News round-up by DDW’s Megan Thomas for 14-18 February, 2022 This week, DDW rounds up updates, approvals, research and trials which will enable scientists to make life-saving developments in the drug discovery industry. 1. Trial launched of HIV vaccine antigens delivered through mRNA technology… Read More
CAS, a division of the American Chemical Society specialising in scientific information solutions, has launched an expansion of the CAS SciFinder Discovery Platform into life sciences. The enhanced platform includes over two million modified biosequences, 60 years of patent literature, and one of the largest collections of journal information… Read More
Registration for SLAS Europe 2022 Conference and Exhibition is open and the society looks forward to welcoming the life sciences community in Dublin at the Royal Dublin Society, a venue that is renowned for hosting scientific gatherings. Keynote speakers include Steve Rees, VP of Discovery Biology… Read More
Open Orphan has released the results from its Covid-19 characterisation study, which was a partnership between hVIVO, Imperial College London, the Vaccine Taskforce and Department of Health and Social Care (DHSC), and the Royal Free London NHS Foundation Trust. The results from this study show that a SARS-CoV-2 human… Read More
Parkinson’s UK and Domainex have collaborated to develop small molecule therapies targeting neuroinflammation that could slow the progression of Parkinson’s Disease. Context Inflammation is vital for defending the body from infections, injuries and toxins. However, in Parkinson’s there is excessive chronic inflammation within the brain. Read More
AstraZeneca’s Saphnelo (anifrolumab) has been approved in the European Union (EU) as an add-on therapy for the treatment of adult patients with moderate to severe, active autoantibody-positive systemic lupus erythematosus (SLE), despite receiving standard therapy. Context Saphnelo is the first biologic for SLE approved in… Read More
Integrated DNA Technologies (IDT) has released Alt-R HDR Donor Blocks, a solution for increasing homology-directed repair (HDR) rates in large fragment knock-in experiments. How does Alt-R HDR work? The Alt-R HDR Donor Blocks incorporate advanced chemical modifications to boost the HDR rates of large genomic… Read More
An in vivo CRS Evaluation Study in humanised mouse models can deliver fast, reproducible, and translatable data about drug safety in just two weeks. A humanised mouse platform offers the unique ability to preclinically analyse a fully systemic response that involves human immune cells and surrounding tissues. Furthermore, the platform… Read More
An in vivo CRS Evaluation Study in humanised mouse models can deliver fast, reproducible, and translatable data about drug safety in just two weeks. A humanised mouse platform offers the unique ability to preclinically analyse a fully systemic response that involves human immune cells and surrounding tissues. Furthermore, the platform… Read More
“Viruses evolve — that’s a fact of life”, says Dr Nick Downey (NGS collaborations lead, Integrated DNA Technologies), Dr Nikki Freed (Auckland Genomics, University of Auckland, New Zealand) and Dr Olin Silander (School of Natural and Computational Sciences, Massey University, New Zealand) in this DDW exclusive. Every time a virus replicates itself, there… Read More
The top 20 global innovative bio/pharma companies* reported a 24.9% growth in aggregate market capitalisation (MCAP)—from $2.8 trillion on 31 December 2020 to $3.4 trillion as of 31 December 2021, according to GlobalData. The data and analytics company notes that a positive year-on-year MCAP growth was reported… Read More
Assessing the safety and efficacy of biotherapeutics is imperative during the drug-development process. In particular, pharmacokinetic (PK) and anti-drug antibody (ADA) assays are conducted to study and evaluate new drug candidates and biosimilars. For PK/ADA assays, anti-idiotype antibodies (Anti-IDs) are powerful tools to measure the concentration of antibody drugs in… Read More
