Author Archives: Megan Thomas

#Clinical trial #Drug development #Drug discovery #Therapeutics

Rani Therapeutics initiates Phase I study osteoporosis drug 

Rani Therapeutics, a clinical stage biotherapeutics company focused on the oral delivery of biologics, has initiated a Phase I study of RT-102, an oral formulation of the human parathyroid hormone analog PTH(1-34) for the treatment of osteoporosis, delivered via capsule.  The first subject has been administered RT-102… Read More

#News

#Covid-19 #Drug discovery #Research

Experts evaluate the effects of ACE2-mediated Covid-19 infection 

Bachem, a Swiss technology company active in the fields of chemistry, biochemistry and pharmaceuticals, as well as the development and production of peptides and oligonucleotides, analyses the findings from scientific research about the relationship between ACE2 and SARS-CoV-2.   Covid-19 has impacted almost everyone’s lives, whether through personal experience of infection… Read More

#Covid-19 #Exclusive Content #News

#Funding #Investment

New biopharma deals report reveals spending trends 

Clarivate has released its annual Biopharma Deals Report, which highlights emerging market trends and features detailed analysis of the key deals of 2021 and potential implications for 2022, the full extent of which can be found on clarivate.com.  This year’s report finds US biotech companies raised the majority of capital… Read More

#News #Trends & Analysis

#AstraZeneca #Covid-19 #Marketing approval authorisation #MHRA

Covid-19 approval milestone for those who can’t be vaccinated 

AstraZeneca’s Evusheld (tixagevimab co-packaged with cilgavimab) has been authorised by the Medicines and Healthcare products Regulatory Agency (MHRA) and is the first antibody combination for pre-exposure prophylaxis (PrEP) against Covid-19 licensed in Great Britain.   The use of this medicine is for adults who are not currently… Read More

#News #Trending News

#Clinical trials #Covid-19 #Healthcare #Public health

Interview: Delivering smart clinical trials for better health 

Following the launch of Protas, an organisation which was launched on January 24, 2022, DDW Editorial Assistant Megan Thomas interviews Protas Chief Executive, Professor Sir Martin Landray, an epidemiologist and physician who has over 20 years’ experience of leading large, randomised clinical trials and has most recently been leading the… Read More

#Covid-19 #Exclusive Content #News #Opinion

#Drug development #Drug innovation #Funding #Investment

CatSci secures £4.5 million funding deal for drug development 

CatSci, a partner for medicines development, has secured £4.5 million of investment to expedite the development and launch of what it calls its life-changing therapeutics.  The company develops economically and environmentally sustainable drug manufacturing processes that enable its global pharmaceutical customers to create affordable small molecule therapeutics… Read More

#News

#AI / data analytics / healthtech / informatics #BioELN #Cell therapy

Webinar: Next generation BioELN

Cellular therapeutics like CAR-T have revolutionised cancer treatment and hold immense promise in other areas of unmet medical need. Developing a new therapeutic cell line is no small task and requires the design and tracking of molecular tools, viral vectors, pluripotent stem cells and more. With projects spanning weeks and… Read More

#News

#Infectious diseases

Liverpool spinout launches to support diagnostic innovation 

Liverpool School of Tropical Medicine (LSTM) has launched a spinout, iiDiagnostics, to enable industry engagement and commercial access to the world-leading diagnostics R&D capability and facilities at LSTM – supporting the discovery and development of innovative diagnostics with the aim of saving lives globally.  First steps … Read More

#News

#Clinical trials #Research study

This week in drug discovery (21-25 March) 

News round-up by DDW’s Megan Thomas for 14-18 March, 2022  New breakthroughs, results, clinical trials and research exemplify the constant and forward-moving trajectory of the drug discovery and development industry in this week’s news round up.  1. Atrogi gets go-ahead to begin Phase I study… Read More

#News

#AI / data analytics / healthtech / informatics #Biotechnology #Drug discovery #Podcast

Scientific data management: What does your lab need? – podcast

This is the latest episode of the free DDW podcast, “Scientific data management: What does your lab need?”. It covers three narrated articles written for Volume 22, Issue 3 – Summer 2021 and Volume 22, Issue 4 – Fall 2021 of DDW.   The articles are… Read More

#News

#Narrated podcasts

Scientific data management: What does your lab need?

This is the latest episode of the free narrated DDW podcast, “Scientific data management: What does your lab need?”. It covers three narrated articles written for Volume 22, Issue 3 – Summer 2021 and Volume 22, Issue 4 – Fall 2021 of DDW. The… Read More

#Podcasts

Francis Crick Institute
#Antimicrobials #Microbiology #Molecular Biology

Research on drug tolerance revealed 

Research from the Francis Crick Institute has revealed a key mechanism that increases tolerance to drugs amongst microbial communities. The findings could help the development of more effective antifungal treatments.    Background  Antimicrobial drug resistance and tolerance occurs when bacteria, viruses, fungi or parasites no… Read More

#News

CAR-T cell
#AI / data analytics / healthtech / informatics #BioELN #Cell therapy

How to track inputs that go into developing cellular therapeutics

Cellular therapeutics like CAR-T have revolutionised cancer treatment and hold immense promise in other areas of unmet medical need. Developing a new therapeutic cell line is no small task and requires the design and tracking of molecular tools, viral vectors, pluripotent stem cells and more. With projects spanning weeks and… Read More

#News

#Covid variants #Covid-19 #Omicron

Are we getting a lead on Omicron subvariant? Study says yes 

New preclinical authentic ‘live’ virus data from Washington University School of Medicine demonstrated that Evusheld (tixagevimab co-packaged with cilgavimab) retains potent neutralising activity against the emerging and highly transmissible Omicron SARS-CoV-2 BA.2 subvariant.1 The data also showed that Evusheld retains activity against Omicron BA.1 and BA.1.1.1. The findings were… Read More

#News #Trending News

#3D modelling #Automation / robotics

Biodispensing platform launched for 3D cell culture automation 

CELLINK, A BICO company, has launched BIO CELLX, a novel system that automates 3D cell culture workflows by leveraging pre-validated protocols.   The platform  The BIO CELLX builds upon CELLINK’s bioprinting portfolio which utilises technologies. By introducing the concept of pre-validated protocols, the platform provides… Read More

#News