Assessing the safety and efficacy of biotherapeutics is imperative during the drug-development process. In particular, pharmacokinetic (PK) and anti-drug antibody (ADA) assays are conducted to study and evaluate new drug candidates and biosimilars.
For PK/ADA assays, anti-idiotype antibodies (Anti-IDs) are powerful tools to measure the concentration of antibody drugs in patient samples and serve as positive controls for anti-drug antibodies (ADA).
Download this app note to learn more about:
- The applications of anti-IDs in PK/ADA assays
- Sino Biological anti-idiotype antibody generation packages
- Case Study #1: Development of anti-IDs targeting bispecific antibodies (BsAbs)
- Case Study #2: Generation of anti-IDs targeting scFv/VHH