Anti-idiotype Antibodies: A Powerful Weapon for PK/ADA Assays

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Assessing the safety and efficacy of biotherapeutics is imperative during the drug-development process. In particular, pharmacokinetic (PK) and anti-drug antibody (ADA) assays are conducted to study and evaluate new drug candidates and biosimilars.

For PK/ADA assays, anti-idiotype antibodies (Anti-IDs) are powerful tools to measure the concentration of antibody drugs in patient samples and serve as positive controls for anti-drug antibodies (ADA).

Download this app note to learn more about:

  • The Applications of Anti-IDs in PK/ADA Assays
  • Sino Biological Anti-Idiotype Antibody Generation Packages
  • Case Study #1: Development of Anti-IDs Targeting Bispecific Antibodies (BsAbs)
  • Case Study #2: Generation of Anti-IDs Targeting scFv/VHH

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