Author Archives: Megan Thomas

#Drug development #Drug discovery #Immuno-oncology #Infectious diseases #Neurodegenerative disorders

This week in drug discovery (26-29 July)

News round-up by DDW’s Megan Thomas for 26-19 July DDW’s Megan Thomas rounds up her top five stories this week which show how innovation in drug discovery is enhanced by collaboration, be it financial backing or through the combining of differing expertise to achieve a common goal. SARS-CoV-2 spike… Read More

#News #Trending News

#AI / data analytics / healthtech / informatics #Automation / robotics #Biopharmaceuticals #Covid-19 #CRISPR #Drug discovery #Immunology / Virology & Vaccines #Lab automation #Moderna #Molecular Biology #Pfizer #Sequencing

What has 2020 taught us about lab automation?

Listen to this article on the DDW Podcast: Dr Patrick Courtney (SiLA consortium), Burkhard Schaefer (SiLA consortium/ASTM AnIML) and Oliver Peter, Senior Director, Senior Group Leader Biology Technologies and Lead Discovery, Biology, Idorsia Pharmaceuticals, look at the importance of automation in the face of global disease. As we write this, vaccines… Read More

#Covid-19 #Exclusive Content #News

#Assays #Biotechnology #Life sciences #Therapeutics

PerkinElmer expands KRAS oncology drug discovery assays

PerkinElmer has released four new ready-to-use AlphaLISA KRAS kits, designed to help scientists better understand complex KRAS protein structures and mutations so they can more easily, quickly, and precisely identify potential new therapeutic candidates for a wide range of prevalent cancers. Researchers will now be able to choose between PerkinElmer’s… Read More

#News

#Cancer immunotherapy #Cancer research #Immuno-oncology #Immunology #Tumour biology

Cancer project enters Immuno-oncology Alliance

In the UK, researchers Professor Andrew Beggs and Professor Gary Middleton from the Institute of Immunology and Immunotherapy and the Institute of Cancer and Genomic Sciences have partnered with Cancer Research UK in a target identification project for the Immuno-oncology Alliance, which translates discovery science into new therapeutics for cancer… Read More

#Cancer Research #News

#Bioscience #Screening

Micro Tissues on Electrospun Scaffolds

In this video, Dr Gary Allenby, CEO Aurelia Bioscience, describes a scientific poster on ‘Magnetic Electrospun Micro-fibre Scaffold Assemblies: Examples of their use for 3-Dimensional Cell-Based Screening Applications’. How the technology works: Aurelia Bioscience has developed a 3-D micro-tissue system from electrospun material that can be used in… Read More

#News #Videos

#Cell and gene therapy #Cell and Gene Therapy Catapult #Gene therapy #Neurodegenerative disorders #Research

Gene therapy enables new treatments for neurodegenerative diseases

The University of Sheffield and the Cell and Gene Therapy Catapult have launched a gene therapy programme which could pave the way for novel treatments for neurodegenerative diseases. The research has been awarded £513,141 from LifeArc and the Motor Neurone Disease Association to test the feasibility and efficiency of a… Read More

#News

#Alzheimer's #Drug development #Pharma #Research

New data supports targeting Trk receptors for treating Alzheimer’s

AlzeCure Pharma’s presentation and poster regarding the clinical candidate drug ACD856 for Alzheimer’s disease, presented at the Alzheimer’s Association International Conference (AAIC) 2021 on July 26-30 in Denver, USA, are now available on its website. The abstract, ACD856 – a novel positive allosteric modulator of Trk-signaling in clinical development for… Read More

#News

Business agreement
#Antibodies #Bioproduction #Flow Cytometry #Life sciences #Proteogenomics #Reagents

PerkinElmer to acquire BioLegend

PerkinElmer has entered into an agreement to acquire BioLegend, provider of life science antibodies and reagents, for approximately US$5.25 billion. The transaction will be the largest in PerkinElmer’s history and is expected to close by the end of the 2021 calendar year, subject to regulatory approvals and other customary closing… Read More

#News

#Antimicrobials #Drug development #Drug discovery #Infectious diseases #R&D

£1.9 million to combat infectious disease and antimicrobial resistance

The Bloomsbury SET, a knowledge exchange programme led by The Royal Veterinary College (RVC), has been awarded £1.9 million from Research England. Beginning in July 2021, the year-long project aims to commercialise research into infectious disease and antimicrobial resistance. Building on the current work of The Bloomsbury SET, this new… Read More

#News

#Covid-19 #Immunology / Virology & Vaccines #Innovation #Technology

Neutralising SARS-CoV-2 infection with shark VNAR antibodies

While the global vaccine roll-out continues, the role of therapeutic antibodies to combat Covid-19 should not be overlooked. Now researchers have identified a novel class of antibodies that appears to have an ability to neutralise the original strain of SARS-CoV-2 and be able to block some of the recent mutations… Read More

#Covid-19 #Editor's Choice #Intelligence #News #Opinion

#Cell culture #Drug discovery #Imaging #Podcast

Automating the cell culture workflow

The guest on this podcast is Dr. Joanna Hawryluk, Product Manager for Research Imaging at Olympus Corporation of the Americas located in Waltham, Massachusetts. She discusses automating the cell culture workflow and explains the importance of cell culture workflow in the drug discovery process and how it can be improved… Read More

#Podcasts

#Biosciences #Drug development #Drug discovery #Narrated podcasts

The benefits of robust colony management in drug discovery

In this podcast John Couse, Vice President of Scientific Services at Taconic Biosciences discusses the benefits of a robust colony management solution/partner in the drug discovery success; how it can enable companies to scale through resource management and create efficiencies. Couse has extensive knowledge of colony managements solutions and outlines… Read More

#Podcasts

#Biosciences #Drug development #Drug discovery #Podcast

The benefits of robust colony management in drug discovery – podcast

In this podcast John Couse, Vice President of Scientific Services at Taconic Biosciences discusses the benefits of a robust colony management solution/partner in the drug discovery success; how it can enable companies to scale through resource management and create efficiencies. Couse has extensive knowledge of colony managements solutions and outlines… Read More

#News

#Biotechnology #Biotherapeutics #Market reporting

Innovation and opportunity within Europe’s biotech sector

Listen to this article on the DDW Podcast: Lu Rahman introduces a slice of European biotech expertise Thanks to the Covid-19 pandemic, the global biotech sector has been thrown into the spotlight, not just in the drug discovery and development word, but as a sector that the general public has come… Read More

#Editor's Choice #Exclusive Content #Intelligence #Market Reports #News #Opinion #Trends & Analysis

#Biochemistry #Drug development #Drug discovery #Life sciences #Microfluidics #Pharmaceuticals

Researchers develop tool to speed up the study of enzymes

Scientists understand that transformations that couldn’t historically be explained by conventional chemistry or physics alone are in fact powered by enzymes – protein molecules comprised of chains of amino acids that act to speed up, or catalyse, the conversion of one kind of molecule (substrates) into another (products). While more… Read More

#News

#Animal testing #R&D #Research

FRAME comment on the new UK animal R&D statistics

The UK government has released a national statistics report, “Annual Statistics of Scientific Procedures on Living Animals, Great Britain, 2020”. DDW recently reported the ABPI comment. The medical research charity FRAME’s Education & Outreach Manager Amy Beale has made further comment. Beale said: “Whilst the headline figures in the… Read More

#News