Author Archives: Megan Thomas

#Events #SLAS

SLAS 2022 Hype Tickets now available 

The SLAS 2022 Call for Abstracts submission period is also a Call for Abstracts contest. You can now submit a podium or poster abstract and receive a Hype Ticket.  This allows one entry into the monthly drawing for a year-long APPLIED subscription as well… Read More

#News

#CAR-T #Cell therapy #GlobalData #Oncology #Tumour biology

Off-the-shelf potential for NK cell therapies for tumour treatment 

Natural killer (NK) cell therapies have the potential to be an effective, off-the-shelf treatment for a range of cancers. Analysis of NK cell therapies, currently in development, reveals that 57% of these are allogeneic therapies, and although development in haematological indications is more advanced, there are a high number of therapies… Read More

#Cancer Research #News

#Assays #Biosciences #Protein chemistry / Proteomics

Protein-protein Interactions Using NanoBRET Technology

In this video, Dr Gary Allenby, CEO Aurelia Bioscience, describes a scientific poster on ‘Protein-protein Interactions Using NanoBRET Technology’. Historically, only solution-based assays were used to screen compounds in PPI, but a more physiological approach is to examine the interaction in living cells. However, there are very few… Read More

#News #Trending News #Videos

#Cancer #Cancer research #Clinical trials #Drug repurposing

Aspirin trialled as potential treatment for aggressive breast cancer 

A new study is trialling whether giving aspirin alongside immunotherapy drug avelumab could improve its effectiveness for people affected by breast cancer.   The clinical trial is being funded by the Breast Cancer Now Catalyst Programme, which aims to accelerate progress in breast cancer research through innovation and collaboration. As… Read More

#Cancer Research #News #Trending News

#Covid-19 #Healthcare #Monoclonal antibodies

First monoclonal antibody treatment for Covid-19 approved for UK 

Following a thorough review of evidence carried out by the Medicines and Healthcare products Regulatory Agency (MHRA) and recommendation by the Commission on Human Medicines (CHM), the UK government’s independent expert scientific advisory body, the MHRA has approved Ronapreve as the first monoclonal antibody combination product indicated for use in the… Read More

#Covid-19 #News #Trending News

#Oncology #Therapeutics

Avacta appoints biotech executive and oncologist to bolster strategy

Avacta has appointed Dr Mark Goldberg as Non-executive Director to the Board with immediate effect. Dr Alastair Smith, Chief Executive Officer of Avacta, said Goldberg’s experience as a biotech executive and oncologist will greatly benefit the strategy and vision for the therapeutic business.  Dr Goldberg is a medical oncologist and haematologist on the faculty… Read More

#Business & Investment #News

#Biotherapeutics #Collaboration #Funding #HIV #Pharma

This week in drug discovery (16-20 August) 

News round-up by DDW’s Megan Thomas for 16-20 August  DDW’s Megan Thomas selects five news stories which spotlight the deals, collaborations and funding keeping the industry moving forward, enabling academics and drug developers to continue with life-saving research.   1. OGT training initiative with CytoCell University … Read More

#News #Trending News

#Antibodies #Immunology / Virology & Vaccines #Malaria #Monoclonal antibodies

Monoclonal antibody prevents malaria in NIH trial 

One dose of a new monoclonal antibody discovered and developed at the National Institutes of Health (NIH) safely prevented malaria for up to nine months in people who were exposed to the malaria parasite. The clinical trial is the first to demonstrate that a monoclonal antibody can prevent malaria… Read More

#News #Trending News

#Cancer immunotherapy #Cancer research #Clinical trials #Immuno-oncology #Immunology / Virology & Vaccines #Tumour biology

Collaboration to develop a novel cancer immunotherapy  

Terumo Blood and Cell Technologies and PhotonPharma have established a memorandum of understanding (MOU) for collaboration to develop Innocell, a novel tumour specific immunotherapy (a therapeutic vaccine)… Read More

#Cancer Research #News

#Biologics / Biotechnology #Collaboration #Drug development

Collaboration aims to accelerate cyro-EM research 

Amgen and the University of Southern California (USC) are working together to provide researchers access to two cryo-transmission electron microscopes (cryo-EMs) – the Thermo Scientific Krios and Glacios.  Access to the two instruments in one shared location allows researchers from both institutions to combine resources to bring more speed and… Read More

#News

#Automation / robotics #Drug discovery #ELRIG #Events #Screening #SLAS

ELRIG’s Drug Discovery 2021 to host SLAS’s Innovation AveNEW 

The European Laboratory Research & Innovation Group (ELRIG) UK has announced programme details for Drug Discovery 2021, which will take place at the Exhibition Centre ACC in Liverpool, UK, from October 19–20. The Society for Laboratory Automation and Screening (SLAS) will host its Innovation AveNEW to showcase emerging innovations and companies. … Read More

#News #Trending News

Covid-19
#Clinical trials #Covid-19 #Immunotherapy #Moderna #mRNA #Pfizer

Study on third Covid-19 vaccine dose in kidney transplant recipients 

A pilot study has begun to assess the antibody response to a third dose of an authorised Covid-19 mRNA vaccine in kidney transplant recipients who did not respond to two doses of the Moderna or Pfizer-BioNTech Covid-19 vaccine. The Phase II trial is sponsored and funded by the National Institute of Allergy and… Read More

#Covid-19 #News

#Pharma #Pharmaceuticals #Therapeutics

Digital brain biomarker start-up appoints Acacia founder to board 

Monument Therapeutics, a stratified medicine company, today announced Monument Therapeutics the appointment of Dr Julian Gilbert to its Board as a Non-Executive Director. Monument recently raised £2.625 million in seed funding and applies a novel drug development strategy, leveraging digital assessments of cognition to match patients with new pharmaceutical treatments.  The… Read More

#Business & Investment #News #Start-up Zone

#Clinical trials #Drug development #Drug discovery

Lung fibrosis drug may help heart failure patients 

An early phase trial of pirfenidone, a drug currently used to treat lung fibrosis, has shown it may also help patients who suffer from a common form of heart failure in a study funded by the National Institute for Health Research, published in Nature Medicine.  Trialed in… Read More

#News

#Biologics / Biotechnology #Covid-19 #HIV #In vivo #Therapeutics

Biotech start-up takes another stride toward flu cure 

Covimro, a British biotech start-up, has developed a food-grade compound which has demonstrated its efficacy against the flu virus in an animal model study carried out by A-IR Clinical Research and Pharmidex Pharmaceutical Services.  The in vivo testing analysed Covimro’s antiviral capability against an infection of Influenza A H3N2, a flu variant consistent with… Read More

#News #Start-up Zone

#Antibodies #Biology #Genes

Sino Biological listed on the Shenzhen Stock Exchange 

Sino Biological has announced a successful listing on the Shenzhen Stock Exchange subsidiary ChiNext. A total of 17 million shares were issued for a total of ¥4.98 billion (US$770 million) raised during this initial public offering.   Sino Biological says the listing is an important milestone in its strategic plan for growth. It signifies a new starting… Read More

#Business & Investment #News