Author Archives: Megan Thomas

#Cancer research #Checkpoint inhibitor therapies #Research #Therapeutics

Agreement signed to profile patients in immuno-oncology trial

Oncimmune Holdings has signed an autoantibody profiling contract with Dana-Farber Cancer Institute in Boston, Massachusetts. Dana-Farber, a clinical affiliate and research institute of Harvard Medical School, is a cancer research organisation and its cancer hospitals have more than 1,100 therapeutic and non-therapeutic clinical trials in progress. Under this agreement, Oncimmune… Read More

#News

#Cell culture #Drug discovery #Imaging #Podcast

Automating the cell culture workflow – podcast

The guest on this podcast is Dr. Joanna Hawryluk, Product Manager for Research Imaging at Olympus Corporation of the Americas located in Waltham, Massachusetts. She discusses automating the cell culture workflow and explains the importance of cell culture workflow in the drug discovery process and how it can be improved… Read More

#Editor's Choice #News

#Antibodies #Biopharmaceuticals #Biotherapeutics #Covid-19 #SARS-CoV-2

Helping Indian biotherapeutic companies advance novel therapeutics

Fusion Antibodies and BioTickle, its distributor in India, are providing local biopharmaceutical organisations with access to biopharmaceutical development capabilities. Since the emergence of Covid-19, Fusion Antibodies has contributed resources into developing a panel of unique protein antigens for use in discovery platforms. To date, the proteins have shown positive profiles… Read More

#News

#Data #Drug discovery #Drug innovation #Life sciences

Paradigm4 launches multi-omics app for advanced cross-study analysis

Paradigm4 has launched Reveal: Multi-Omics, an app which allows researchers to undertake advanced, cross-study analyses and enable quick searches for genes and proteins across integrated public reference and proprietary datasets. It is built on top of Paradigm4’s SciDB analytics platform, designed for rapid data slicing that enables scientific data modelling,… Read More

#News

#Blood donation #Drug development #Research

BioIVT opens UK blood donor centre at London’s White City Campus  

BioIVT has moved its London blood donor centre to Imperial College London’s White City Campus, which is four times larger than its previous facility. BioIVT has seven global blood donor centres and supports the work of about 30,000 researchers worldwide. “We are responding to a rapidly… Read More

#News

#Awards #Biopharmaceuticals #Biotechnology #Clinical trials

Frost & Sullivan announces DCT award winner 

Thread, a technology and service provider for decentralised clinical trials, has been awarded a Frost & Sullivan award. The company scooped the Frost & Sullivan’s 2021 Customer Value Leadership Award in the decentralised clinical trials industry. “Thread’s innovations via its decentralised trials platform are sure… Read More

#News

#Covid-19 #Drug development #Drug discovery #Pharmaceuticals #RNA #SARS-CoV-2

SARS-CoV-2 spike protein induces lipid stripping from cell membrane

Scientists at the Institut Laue-Langevin (ILL), in collaboration with the Paul Scherrer Institut (PSI), the Institut de Biologie Structurale (IBS) and the Australian Nuclear Science and Technology Organisation (ANSTO), have published new data on how the SARS-CoV-2 spike protein interacts with mammalian lung cell membranes, allowing the viral… Read More

#Covid-19 #News #Trending News

#Biology #Cancer #Cancer research #Drug discovery #Therapeutics

Researchers develop novel therapy that could be effective in many cancers

Mount Sinai researchers have developed a therapeutic agent that shows high effectiveness in vitro at disrupting a biological pathway that helps cancer survive, according to a paper published in Cancer Discovery. The therapy is an engineered molecule called MS21 that causes the degradation of AKT, an enzyme that is overly… Read More

#Cancer Research #News #Trending News

#AI #Biology #R&D #Therapeutics #Tumour biology

Combining AI-driven drug capabilities with CDK targets for oncology

Exscientia and GT Apeiron Therapeutics have entered an R&D collaboration. Exscientia’s AI expertise will  be used to accelerate the discovery of multiple small molecule therapeutic drug candidates designed to selectively treat aberrant cell cycle driven cancers and build a pipeline of CDK novel therapies. This collaboration follows the design of… Read More

#News

#Assay development optimisation & technology #Assays #Drug discovery #Drug toxicity #In vitro #Podcast

Podcast: Paving the way for optimum drug discovery

This is the latest episode of the free DDW podcast, “Paving the way for optimum drug discovery”. It covers two narrated articles written for Volume 22, Issue 1 – Winter 2020/21 of DDW and they are read aloud by Megan Thomas. These articles are titled: “In vitro models for assessing… Read More

#News

#Podcast

Paving the way for optimum drug discovery

This is the latest episode of the free DDW podcast, “Paving the way for optimum drug discovery”. It covers two narrated articles written for Volume 22, Issue 1 – Winter 2020/21 of DDW and they are read aloud by Megan Thomas. These articles are titled: “In vitro models for assessing… Read More

#Podcasts

#Biotherapeutics #Clinical trials #Drug development #Drug discovery #Pharma #Rare disease

This week in drug discovery (19 – 23 July)

News round-up by DDW’s Megan Thomas for 19 – 23 July DDW’s Megan Thomas rounds up her top five stories this week which facilitate the continuation of vital drug discovery research, from partnerships and funding to successful trials and informative reports. Exscientia accelerates Covid-19 drug discovery using AI Exscientia… Read More

#News #Trending News

#Drug development #Drug innovation #Funding #Research #Therapeutics

Orbit Discovery plans growth in peptide discovery business

Orbit Discovery has raised US$7.6 million which will be used to accelerate its growth as a provider of peptide discovery services to the biotechnology and pharmaceutical industry. Orbit Discovery’s novel bead-based and microfluidic technology platform enables the screening of peptide libraries for target binding and subsequent activity in cell-based functional… Read More

#News

#Biotherapeutics #Drug development #Parkinson's

Innovative CNS medicines partnership announced

Bial and Medis have partnered on two of Bial’s proprietary drugs: Zebinix (eslicarbazepine acetate) and Ongentys (opicapone). The established partnership comprises an exclusive distribution agreement for Zebinix in the Czech Republic and Slovakia and an exclusive distribution agreement for Ongentys in Bosnia and Herzegovina, Bulgaria, Croatia, the Czech Republic, Estonia,… Read More

#News

#Biosciences #Clinical trials #Drug delivery #Drug discovery #High throughput screening #Therapeutics

Mini-library approach delivers an arsenal in drug development pipeline

Listen to this article on the DDW Podcast: Dr. Naganna Nimishetti, Chief of the Small Molecule Drug Discovery Division (SMDD) and Dr. Dun Yang, CEO/CSO of Anticancer Bioscience, a precision therapeutics company headquartered in Chengdu, China, explain how the company is identifying bioactive hits using libraries of less than 100 compounds. Read More

#Editor's Choice #Exclusive Content #News

The road to global pharmacogenomics

Listen to this article on the DDW Podcast: Dr Richard O’Kennedy, Vice-President for Research, Development and Innovation at Qatar Foundation, looks at the global potential within pharmacogenomics. Twenty years on since the first human genome was sequenced, pharmacogenomics has the capacity to significantly change the world of medicine. The term pharmacogenomics… Read More

#Exclusive Content #News