Genetics / genomics

#Drug development #Drug discovery #Gene therapy #Genetics / genomics #mRNA

New DDW Highlights podcast: 10 October 2023

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates.  In celebration of the Nobel Prize for Medicine going to two of… Read More

#News

CRISPR gene editing
#CRISPR #Funding #Genetics / genomics #National Institutes of Health (NIH) #Neuroscience #Yale University

NIH awards ‘bench-to-bedside’ grant for CRISPR drug development

The National Institutes of Health has awarded the first phase of a roughly $40m grant to Yale University to advance a novel CRISPR-based gene-editing delivery platform for the targeted treatment of neurogenetic diseases. The two diseases being targeted in the project are Angelman syndrome and H1-4… Read More

#News

#Drug development #Drug discovery #Gene therapy #Genetics / genomics #mRNA

This week in drug discovery (2-6 October)  

News round-up for 2-6 October by DDW Digital Content Editor Diana Spencer. In celebration of the Nobel Prize for Medicine going to two of the early proponents of mRNA technology for creating therapeutics, Katalin Karikó and Drew Weissman, this week our round-up highlights the importance of… Read More

#News

Human brain
#Depression #Genetics / genomics #Korea #Major depressive disorder #Mouse models #Neuroscience

Researchers uncover molecular pathways underlying depression

Scientists have discovered the link between gene expression, DNA methylation, and brain structural changes in depression, revealing new potential therapeutic targets. By analysing gene interactions in mice subjected to behavioural tests, the researchers from Korea University Anam Hospital, Konkuk University, and Sahmyook University identified 141 genes… Read More

#News

3d structure of the protein molecule
#Collaboration #Genetics / genomics #Partnership #Proteomics #Structural Genomics Consortium #X-Chem

Partners collaborate to unlock the human proteome

X-Chem and the Structural Genomics Consortium (SGC) have entered a collaboration aimed at creating new chemical tools to study human proteins. The goal is to generate DNA-encoded library (DEL) screening data for large numbers of under-addressed proteins in the human proteome – ultimately allowing drug discovery… Read More

#Business & Investment #News

Large intestine
#Francis Crick Institute #Genetics / genomics #Inflammatory Bowel Disease #King's College London #T cell activation

Specialised T cells could offer way to repair the gut barrier

Researchers from the Francis Crick Institute, King’s College London and Guy’s and St Thomas’ NHS Foundation Trust in the UK have characterised a specialised type of immune cell, which plays a key role in protecting and repairing the cells in the healthy human gut. The researchers… Read More

#Editor's Choice #News

Cancer cell
#Biomarkers #Breast cancer #Cancer research #Genetics / genomics #Oncology #Personalised medicine #The Institute of Cancer Research

Genetic biomarkers could personalise therapy for TNBC

A new study has shed light on the genetic messages encoded by genes within ‘triple negative’ breast cancers (TNBC), and shows they could predict response to chemotherapy. The study, by researchers at The Institute of Cancer Research, London, shows that certain characteristics within patients’ primary tumours… Read More

#Cancer Research #News #Trending News

#AI / data analytics / healthtech / informatics #Cancer research #Genetics / genomics #Interview #Oncology #Sitting Down With

Sitting down with… Neil Dhawan

Listen to this article on the DDW Podcast: Reece Armstrong speaks to Neil Dhawan, the Co-founder and CEO of Totus Medicines about the company’s approach to drug discovery using fundamental technologies in chemistry, biology and artificial intelligence (AI). RA: How is Totus Medicines attempting to… Read More

#Cancer Research #Exclusive Content

Map of Latin America
#AI / data analytics / healthtech / informatics #Biomedical research #Genetics / genomics #Latin America and the Caribbean (LAC) #Lifebit

Partners tackle global health challenges through genomics

UK-based precision medicine software provider Lifebit has agreed partnerships with two population genomic initiatives in Mexico and Brazil to help diversify genomic research and reduce health inequality in Latin America. Lifebit’s platform provides a secure way for research organisations to access global biomedical data – helping… Read More

#News

#AI / data analytics / healthtech / informatics #Cancer research #Genetics / genomics #Oncology

Open science, genomics, and the quiet revolution in our approach to pharma

Listen to this article on the DDW Podcast: Evan Floden, CEO of Seqera Labs examines how data sharing platforms are impacting cancer and genomics research. The tide has been turning in the worlds of diagnostics and drug development. Bioinformatics and genetic sequencing are… Read More

#Cancer Research #Exclusive Content

Long Covid
#Chronic Fatigue Syndrome #Covid-19 #Genetic profiling #Genetics / genomics #Long Covid

Ground-breaking study identifies novel drug targets for long Covid

A study into long Covid has provided the first detailed genetic insights into the condition and its commonalities with other diseases, including myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Despite considerable global research, studies have so far failed to identify the detailed genetic risk factors for long Covid,… Read More

#News #Trending News

#AMR #Covid-19 #Diabetes #Drug development #FDA #Genetics / genomics #Influenza #Parasitic disease

New DDW Highlights podcast: 10 July 2023

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates.  It’s been a fascinating week in drug discovery, as AstraZeneca announced that its Phase III trial… Read More

#News

#Camena Bioscience #Financing #Funding #Genetics / genomics #Synthetic biology

Synthetic biology company raises $10m in financing round

Camena Bioscience has closed a $10m Series A financing round, which will be used to scale operations and continue development of DNA synthesis platform gSynth. Synthetic genes are widely used by researchers to understand the mechanisms of disease, and in the drug discovery process to combat… Read More

#News

#AMR #Covid-19 #Diabetes #Drug development #FDA #Genetics / genomics #Influenza #Parasitic disease

This week in drug discovery (3-7 July)  

News round-up for 3-7 July by DDW Digital Content Editor Diana Spencer. It’s been a fascinating week in drug discovery, as AstraZeneca announced that its Phase III trial of datopotamab deruxtecan did not meet its second primary endpoint and saw an 8% drop in its stock… Read More

#News