Genetics / genomics

Endometriosis
#Endometriosis #Genetics / genomics #Personalised medicine #PrecisionLife #University of Oxford #Women's health

Endometriosis partners to discover personalised treatments

PrecisionLife and the University of Oxford have signed a data access agreement to license the Oxford Endometriosis Gene (OXEGENE) dataset to develop new personalised treatments for endometriosis patients. Endometriosis affects 10% of women globally, but on average it takes over seven years for patients to receive… Read More

#News

Chickens
#Genetics / genomics #Immunology / Virology & Vaccines #Influenza #Pandemic prevention

Human gene that defends against avian flu discovered

New research has found a key human gene responsible for blocking most avian flu viruses from spilling over into people. The international study into the pandemic potential of avian flu, which is led by scientists at the MRC-University of Glasgow Centre for Virus Research (CVR), identified… Read More

#Editor's Choice #News

Genomics
#Drug discovery #Gene editing #Genetics / genomics #Genome editing #The Jackson Laboratory #Transcriptomics

eBook: The impact of genomics on drug discovery

The latest eBook by DDW ‘The impact of genomics on drug discovery: Creating new opportunities’ is out now. This 24-page eBook sponsored by The Jackson Laboratory looks at the key use-cases for genomics and how it is improving drug discovery and development projects. Download this exclusive eBook to learn… Read More

#News

#Drug discovery #Gene editing #Genetics / genomics #Genome editing #The Jackson Laboratory #Transcriptomics

The impact of genomics on drug discovery: Creating new opportunities

This 24-page eBook sponsored by The Jackson Laboratory looks at the key use-cases for genomics and how it is improving drug discovery and development projects. Download this exclusive eBook to learn more about: If animal genomics can help find therapies for human disease Key challenges and drivers of the genomics market How… Read More

#DDW eBooks #Intelligence

Approval stamp
#AAV #Advanced Therapy Medicinal Products (ATMPs) #Cell and gene therapy #Gene therapy #Genetics / genomics #Muscular dystrophy #Sarepta Therapeutics

FDA approves first gene therapy for Duchenne muscular dystrophy

Sarepta Therapeutics’ Elevidys has become the first gene therapy for Duchenne muscular dystrophy (DMD) to gain marketing authorisation in the US. The Food and Drug Administration (FDA) has granted accelerated approval to Elevidys (delandistrogene moxeparvovec-rokl), an adeno-associated virus (AAV) based gene therapy for the treatment of… Read More

#News #Regulatory #Trending News

Genomics
#Europe #Genetics / genomics #Genomics #Immunotherapy #Oncology #Personalised medicine #The European Confederation of Pharmaceutical Entrepreneurs (EUCOPE)

Coalition will promote access to genomic profiling in Europe

The European Confederation of Pharmaceutical Entrepreneurs (EUCOPE), Exact Sciences, Guardant Health, Illumina, MSD and Novartis have come together to launch the European Coalition for Access to Comprehensive Genomic Profiling (ECGP). It is hoped that the Coalition will improve cancer care through increased routine clinical access and… Read More

#News

Innovation
#Advanced Therapies #Animal models #Autoimmune disease #Cell and gene therapy #Data #Genetics / genomics #Immunology #Pharma

New podcast on animal genomics, immunology and CGTs

This is the latest episode of the free DDW narrated podcast, “What’s at the forefront of innovation?” It covers three articles written for the for Volume 23, Issue 2 – Spring 2022 of DDW. They are called “Can animal genomics help find… Read More

#News

Neurons
#AAV #Genetics / genomics #High throughput screening #Neuroscience #Sania Therapeutics #University College London

Start-up will focus on medicines for neural circuit dysfunction

Sania Therapeutics, a new company focused on developing genetic medicines for neural circuit dysfunction, has launched at the American Society of Gene & Cell Therapy (ASGCT) conference. The company’s approach combines adeno-associated viruses (AAV) in human neural circuits with tuneable conditionally-activated ion channels. This corrects dysfunctional… Read More

#Business & Investment #News

Structure of the eye
#Genetics / genomics #Ophthalmology #Regenerative Medicine #Université de Montréal

New technique could restore vision in retinal disease

Researchers at Université de Montréal have discovered a way to potentially restore vision in patients suffering from degenerative retinal disease. Published in Proceedings of the National Academy of Sciences, the research was led by UdeM medical professor Michel Cayouette, Director of Cellular Neurobiology Research at the… Read More

#Editor's Choice #News

#Drug development #Drug discovery #Genetics / genomics #Mass spectrometry / NMR

The path to improved safety of gene-based products

Listen to this article on the DDW Podcast: Kerstin Pohl, Senior Global Marketing Manager, Gene Therapy & Nucleic Acid at SCIEX, looks at the application of liquid chromatography-mass spectrometry for analysing host cell proteins. Gene-based therapeutics and vaccines hold immense potential for more… Read More

#Exclusive Content

Genetics
#Cancer research #Gene mutation #Genetics / genomics #Oncology #Precision medicine

3D genomics and targeted cancer therapies

Listen to this article on the DDW Podcast: Anthony Schmitt, PhD, Senior Vice President, Science at Arima Genomics, discusses the applications of 3D genomics in cancer research. Efforts to fulfil the promise of precision medicine, including the use of targeted cancer therapies, necessitate that… Read More

#Cancer Research #Exclusive Content

Genome editing
#Cancer research #Genetics / genomics #Immunotherapy #LambdaGen #Oncology #Partnership #Plasticell

UK-Singapore alliance focuses on cellular immunotherapy

UK company Plasticell and Singapore-based LambdaGen have entered into a strategic collaboration to exploit genome editing technologies based on synthetic lambda integrases that allow specific insertion of large gene cassettes into the human genome. The UK-Singapore partnership is in part financed by a EUREKA GlobalStars competitive… Read More

#News

Next-generation sequencing
#Cancer research #Genetics / genomics #Next generation sequencing #Oncology #Personalised medicine #RNA sequencing #The Tecan Group #Webinar

Free webinar today: How is NGS informing oncology drug discovery?

Join this free webinar to learn about the biggest challenges and opportunities facing the next-generation sequencing (NGS) oncology space. Hosted by DDW and supported by Tecan, “How next-generation sequencing is informing oncology drug discovery” will be free to attend at 7AM PST / 10AM EST… Read More

Webinar date:
Brought to you by Tecan
#News

Gene sequence
#AACR 2023 #Cancer research #Gene mutation #Genetics / genomics #Oncology #Whole genome sequencing

Exome sequencing proves current cancer risk testing is inadequate

Exome sequencing correctly identified individuals with cancer predisposition syndromes who would have been missed by current screening guidelines, according to results from the Tapestry clinical trial. Data presented at the AACR Annual Meeting 2023 showed that among individuals who consented to whole-exome sequencing and were identified… Read More

#Cancer Research #News #Trending News

Genetic sequencing in the lab
#Cancer research #Genetics / genomics #Next generation sequencing #Oncology #Personalised medicine #RNA sequencing #The Tecan Group #Webinar

Register now to learn how NGS is informing oncology drug discovery

Join this free webinar to learn about the biggest challenges and opportunities facing the next-generation sequencing (NGS) oncology space. Hosted by DDW and supported by Tecan, “How next-generation sequencing is informing oncology drug discovery” will be free to attend on April 24 at 7AM PST… Read More

Webinar date:
Brought to you by Tecan
#News