Registration is now open for the DDW Turning Science into Business Symposium. It will take place at the Francis Crick Institute in London on 4 November 2025. Register here for tickets. The half day event boasts a stellar line up… Read More
Scientists have shown for the first time that some of the most persistent cancer cells in glioblastoma rely on transforming growth factor beta-activated kinase 1 (TAK1) for survival and that inhibiting this enzyme leads to the death of the cells. Furthermore, they have demonstrated that it is… Read More
DDW Editor Reece Armstrong takes a look at some recent advances in screening that are helping scientists in the drug discovery process. Screening is an essential part of the drug discovery process in which researchers analyse large libraries of compounds in order to discover promising molecule that demonstrate a… Read More
Join DDW for this free event, ‘CRISPR screening at scale: Achieving 1M cell data sets with an instrument-free, cost-effective approach‘, which is supported by Scale Biosciences. The event will take place on 25 April 5 PM BST / 6PM CEST / 9AM PST. Read More
Join DDW for this free event, ‘CRISPR screening at scale: Achieving 1M cell data sets with an instrument-free, cost-effective approach‘, which is supported by Scale Biosciences. The event will take place on 25 April 5 PM BST / 6PM CEST / 9AM PST. Read More
Join DDW for this free event, ‘CRISPR screening at scale: Achieving 1M cell data sets with an instrument-free, cost-effective approach‘, which is supported by Scale Biosciences. The event will take place on 25 April 5 PM BST / 6PM CEST / 9AM PST. Read More
Join DDW for this free event, ‘CRISPR screening at scale: Achieving 1M cell data sets with an instrument-free, cost-effective approach‘, which is supported by Scale Biosciences. The event will take place on 25 April 5 PM BST / 6PM CEST / 9AM PST. Read More
Pooled CRISPR screens offer the ability to knock out or perturb many genes in a single experiment from several hundred to tens of thousands of targets in parallel. Genome-wide screens are becoming the standard for drug discovery to power unbiased identification of drug targets across gene regulatory networks. Requiring single-cell… Read More
Steve Wowk, VP, Business Unit and General Management of Integrated DNA Technologies, shared with DDW the value of CRISPR-Cas9 in drug discovery. Some of the most important breakthroughs in pharmaceutical research were adapted from naturally occurring phenomena. The CRISPR-Cas9 system, awarded the Nobel Prize in… Read More
Avtar Singh is a Senior Scientist in the Cell and Tissue Genomics Department at Genentech, where he develops new approaches for image-based screening and high-throughput biological discovery. DDW’s Megan Thomas spoke with Singh about SLAS2023, where he presented Image-based screening of pooled genetic libraries. MT: Why is SLAS2023 a prime… Read More
The fifth CRISPR in Drug Discovery: From Targets to Therapeutics meeting will be held face to face In Oxford on February 7-8, 2023. The meeting will focus on the application of genome engineering in identification of novel drug targets through large-scale CRISPR based functional genomics studies, developing advanced cellular… Read More
Genome engineering company Synthego has launched a portfolio of Engineered Cell Libraries to help improve access to CRISPR-edited cells for direct use in functional screening assays. The company’s Engineered Cell Libraries are designed to provide speed, scalability, and efficiency to accelerate the drug discovery… Read More
Join DDW, supported by Horizon Discovery for this exclusive free event which will examine CRISPR-Cas9 screening and how it offers a powerful approach to advancing drug discovery and the understanding of genetic disease. The event will take place on 9 June 2022, 3PM BST. Register for free here. Joanna… Read More
Join DDW, supported by Horizon Discovery for this exclusive free event which will examine CRISPR-Cas9 screening and how it offers a powerful approach to advancing drug discovery and the understanding of genetic disease. The event will take place on 9 June 2022, 3PM BST. Register for free here. Joanna… Read More
Join DDW, supported by Horizon Discovery for this exclusive free event which will examine CRISPR-Cas9 screening and how it offers a powerful approach to advancing drug discovery and the understanding of genetic disease. The event will take place on 9 June 2022, 3PM BST. Register for free here. Joanna… Read More
Over recent years, interest in identifying new targets to modify an immune response to control a host of human diseases has sky-rocketed. Based in part on the success of several new immune cell targeted treatments for cancer, combined with the CRISPR-Cas revolution and the ability to culture primary immune cells… Read More
