Resources

Guide

Cancer therapy guide 

This guide examines how cell and gene therapy transform cancer treatment. While cell therapies like CAR-T are promising cancer treatments, many challenges remain, including improving responses in blood cancers and efficacy in solid tumours. This new cancer therapy guide from 10x Genomics will outline: Cutting-edge single cell and spatial analysis technologies to unlock molecular insights  The discovery […]

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Whitepaper

What makes a great BioELN: whitepaper

John Conway of 20/15 Visioneers tackles defining What Makes a Great BioELN in this thoughtful and informative industry perspective. What you will learn: The six high-level workflows a great BioELN must include What are the team personas who must get utility from a new BioELN The 3 key qualities necessary to have in place before […]

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App Note

Flow cytometry protocols for extracellular & intracellular targets

Flow cytometry is a high throughput quantitative analysis tool that employs fluorescent-labelled molecules for multi-parametric analysis of millions of individual cells or particles. In biomedical sciences, the flow cytometry assays involve a careful selection of antibodies, fluorochrome labels for detection, and often requires optimisation of protocols for an accurate analysis of sample specific target antigens. […]

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White Paper

Maximising Outsourcing Models Beyond Time and Cost

In this whitepaper, we will expand on key factors – cost, time, and innovation – and illustrate how integrating these factors will minimise the challenges and ensure success in outsourcing drug discovery. Learn about: Opportunities, options, and outsourcing of drug discovery programs Hidden costs vs. hidden value Impact on timelines How innovation is driving success

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White Paper

Reduce Your Clinical Study Budget by 55% with a CRO in CEE

Download this Whitepaper by Research Professionals CRO to learn how to reduce your clinical study budget by 45-55% in Central and Eastern Europe. This whitepaper identifies the most significant cost elements of a typical clinical study budget and breaks it down line by line so you can maximise your cost savings when you conduct a […]

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White Paper

Frost and Sullivan Industry Experts White Paper: Cancer Vaccines

Download the white paper to hear from leading industry experts in this emerging field who discuss: Challenges related to antigen and adjuvant selection Vaccine design Immune response improvement Future treatment options

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White Paper

A New Way To Study Cytokine Release Syndrome

An in vivo CRS Evaluation Study in humanised mouse models can deliver fast, reproducible, and translatable data about drug safety in just two weeks. A humanised mouse platform offers the unique ability to preclinically analyse a fully systemic response that involves human immune cells and surrounding tissues. Furthermore, the platform also allows for efficacy testing […]

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App Note

Anti-idiotype Antibodies: A Powerful Weapon for PK/ADA Assays

Assessing the safety and efficacy of biotherapeutics is imperative during the drug-development process. In particular, pharmacokinetic (PK) and anti-drug antibody (ADA) assays are conducted to study and evaluate new drug candidates and biosimilars. For PK/ADA assays, anti-idiotype antibodies (Anti-IDs) are powerful tools to measure the concentration of antibody drugs in patient samples and serve as […]

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App note

SARS-CoV-2 detection workflow in wastewater

Monitoring wastewater for SARS-CoV-2 – or Coronavirus as it is more commonly known – can be a valuable data resource for an effective Covid-19 management. However, there are several challenges involved in detecting biological parameters in wastewater. Fortunately, there are also several solutions available to overcome them. Wastewater can be a carrier medium of SARS-CoV- […]

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Guide

Flow Cytometry Basics Guide

Flow cytometry is a powerful tool allowing you to detect, measure, and quantify single cells or particles in suspension as they pass through a laser. However, to produce impactful results, experiments must be designed with care. This guide takes you through the fundamentals of flow cytometry, provides useful practical advice to optimise your experiments and […]

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App Note

Targeting kinases involved in the innate immune response 

Clinical trials continue to determine whether therapeutic modulation of kinases can be used to suppress the immune system in autoimmune diseases or stimulate for antiviral and cancer immunotherapy. The discovery and characterisation of small molecule modulators have aided these efforts.   The Transcreener ADP² Kinase Assay meets this need as it relies on direct ADP detection to measure the activity […]

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TechNote

Radioactivity Assays for Methyltransferases

SAMDI Tech’s radioactivity assays overcome key challenges in drug discovery by offering key solutions, including: Detecting low amounts of product with sensitive assays Generating data rapidly with high-throughput, 384-well capabilities Characterising potent inhibitors by benefiting from lower enzyme concentrations In this free to download TechNote, learn how SAMDI Tech’s radioactivity assay characterised low turnover methyltransferase […]

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eBook

Antibody Production

In immunoassays-based research, immunodiagnostics, as well as immunotherapy, one of the highly critical aspect of antibodies is their reproducible performance. Antibody reproducibility is driven by their specificity and several other factors ranging from antibody design to target validation. This NEW eBook Antibody Production gives you an overview of the antibody’s life cycle by covering the following sub-topics: […]

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Whitepaper

Bridging the throughput gap: Process optimisation in antibody discovery workflows

Discover how process optimisation utilising automated synthetic biology solutions can remove the antibody sequence cloning bottleneck that divides high-content lead identification and downstream high throughput characterisation. If your work involves antibody discovery or process improvement in recombinant cloning don’t miss this whitepaper illustrating how Codex DNA’s synthetic biology solutions can accelerate antibody discovery workflows. In […]

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Interview

Advantages of conducting clinical studies with CROs in Central and Eastern Europe

Discover how Central and Eastern Europe (CEE) provides an attractive environment to conduct clinical studies of any phase while partnered with a local CRO. Research Professionals’ Managing Partner, György Barta (PharmD) discusses the many benefits of conducting clinical studies in CEE as well how Research Professionals, a leading CRO with operations in Hungary, Poland, Romania, […]

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Case Study

Partnering with drug discovery service providers: challenges and solutions

Drug discovery contract research organizations (CROs) offer an established infrastructure and experience that offers promising paths forward for various research projects. However, partnering with a CRO also presents key challenges, and companies should consider three questions: How long until data is delivered? Will the quality of the data instill confidence in a critical go/no-go decision? […]

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