Resources

#Drug discovery

App Note: Unlock the Power of Multiplexing for High-Throughput Single-Cell Analysis and Isolation

Discover Cyto-Mine® Chroma and picodroplet technology for advanced single-cell analysis: Multiplexing: Simultaneously detect and isolate rare secreting cells using secreted and cellular markers. Ultra-High-Throughput: Efficiently process and sort millions of cells with high accuracy. Cell viability: Maintain high viability and accuracy using complex assays. Download the application note to transform… Read More

#App Notes

#Drug discovery

Whitepaper: Accelerating CMC Strategies for Fab and Fc-Fusion Protein Development

Download the whitepaper to learn more about: Comprehensive CMC Solutions: Explore integrated Chemistry, Manufacturing, and Controls (CMC) strategies tailored to the unique challenges of Fab and Fc-Fusion protein development. Overcoming Complexity: Learn how flexible approaches can streamline the development of complex protein formats, ensuring robust and scalable manufacturing processes. Read More

#Whitepapers

#Drug discovery

Whitepaper: Standardising Data: Why do it and how?

Standardisation is critical to extracting the full potential of analytical data—in facilitating data-driven science and AI/ML-powered innovation. This whitepaper will help you: Review currently available standard formats Understand the pros and cons of open and proprietary formats Ensure data is adequately prepared for scientists and AI/ML applications… Read More

#Whitepapers

#Artificial intelligence (AI) #Automation / robotics

Scientific Note: Optimise your NGS workflows: 5-day path to sequencing

This scientific note explores: The benefits of vendor-qualified protocols, incl. reducing start-up process. The three levels of automated library preparation readiness. How fully vendor-qualified libraries enable sequencing in as few as 5 days. The importance of choosing providers with NGS expertise. Case studies comparing custom vs. vendor-qualified solutions deployment. Read More

#Scientific Notes

#Automation / robotics

Digital Article: Effortless lab automation – Unlock insights for greater efficiency

Explore how advanced lab automation technologies are revolutionizing life sciences laboratories. This article provides actionable insights into integrating automation for increased efficiency and scalability. Key takeaways: Optimize workflows: Learn how automation reduces manual effort, increases throughput, and accelerates timelines. Overcome barriers: Understand strategies to simplify adoption and address workforce challenges. Read More

#Digital Articles

#Drug discovery

App Note: Efficient screening of copolymer nanodiscs to optimize membrane proteins for cryo-EM

With the use of innovative solubilization approaches, such as synthetic copolymers, structural biologists can efficiently create soluble membrane proteins optimized for cryo-EM workflows. In this application note, learn how to screen for the optimal copolymers using a combination of parameters from the Prometheus Panta instrument for stability characterization of membrane proteins. Read More

#App Notes

#Drug discovery

eBook: Optimize Your Preclinical Research with Genetically Engineered Mouse Models

This guide explores key considerations for generating and managing genetically engineered mouse models (GEMs) to accelerate and optimize preclinical research programs. Generating GEMs: three cutting-edge technologies you need to know. Five key components of effective colony management. How integrated solutions can unlock the full potential of preclinical research. Read More

#eBooks

#Drug discovery

App Note: Development of robust co-culture models with human iPSC-derived microglia and excitatory neurons

Download this application note to learn more about: Co-culture methods for ioMicroglia with wild type and disease model ioGlutamatergic Neurons. Assay optimisation for a live cell in vitro neuronal activity assay. Solutions for visualisation and quantification of changes in co-culture health, morphology, function and marker expression.  … Read More

#App Notes

#Neuroscience

App Note: Disease modelling with genetically matched iPSC-derived excitatory neurons

Download bit.bio’s application note to learn more about: Functional characterisation of human iPSC-derived ALS disease models using high throughput MEA. Phenotypic data showing reduced neuronal activity and network formation in ALS disease models. A genetically matched system in ioGlutamatergic Neurons that can be used to identify, measure and rescue disease-related… Read More

#App Notes

#Automation / robotics

Case Study: Automating Cell-Based Assays to Determine Viral Vector Titer

In this Case Study, Oxford Biomedica, an innovative global gene and cell therapy company, describes: The automated system used for a 10-day cell-based workflow required for an analytical test to determine viral vector titer The advantages of Hamilton’s CECULA Graphical User Interface (GUI) for the planning of long-term cell-based assays… Read More

#Case Studies

#Drug discovery

Technical Note: EtoxiClear®: Optimizing endotoxin removal

In this technical note you will learn more about: Targeted and efficient endotoxin removal: EtoxiClear® is a highly effective chromatography affinity adsorbent, specifically designed to remove low residual levels of endotoxins across a variety of biopharmaceutical processes, ensuring high product purity Scalability and cost-effectiveness: Designed for both small and large-scale… Read More

#Technical Notes

#Drug discovery

Smart note: Reduce costs, while continuing to safeguard samples, by raising the setpoint for ULT freezers from –80°C to –70°C

Download this smart note to learn more about: Energy savings: Discover how setting your Thermo Scientific™ TSX™ Universal Series ULT freezers to –70°C can help reduce energy consumption by up to 37% Sample integrity: Learn why most biological samples, including crucial nucleic acids, bacteria, and viruses, remain stable at –70°C… Read More

#Smart Notes