Resources

Advancements in antibody engineering technologies have greatly enhanced the generation of recombinant antibodies in various formats as therapeutic agents. There are already more than 100 antibody-based drugs approved by the FDA, and numerous antibodies are currently in their late-stage clinical studies. Compared to monoclonal antibodies produced using traditional hybridoma techniques, recombinant antibodies offer advantages, such […]

This guide examines how cell and gene therapy transform cancer treatment. While cell therapies like CAR-T are promising cancer treatments, many challenges remain, including improving responses in blood cancers and efficacy in solid tumours. This new cancer therapy guide from 10x Genomics will outline: Cutting-edge single cell and spatial analysis technologies to unlock molecular insights  The discovery […]

John Conway of 20/15 Visioneers tackles defining What Makes a Great BioELN in this thoughtful and informative industry perspective. What you will learn: The six high-level workflows a great BioELN must include What are the team personas who must get utility from a new BioELN The 3 key qualities necessary to have in place before […]

Flow cytometry is a high throughput quantitative analysis tool that employs fluorescent-labelled molecules for multi-parametric analysis of millions of individual cells or particles. In biomedical sciences, the flow cytometry assays involve a careful selection of antibodies, fluorochrome labels for detection, and often requires optimisation of protocols for an accurate analysis of sample specific target antigens. […]

In this whitepaper, we will expand on key factors – cost, time, and innovation – and illustrate how integrating these factors will minimise the challenges and ensure success in outsourcing drug discovery. Learn about: Opportunities, options, and outsourcing of drug discovery programs Hidden costs vs. hidden value Impact on timelines How innovation is driving success

Download this Whitepaper by Research Professionals CRO to learn how to reduce your clinical study budget by 45-55% in Central and Eastern Europe. This whitepaper identifies the most significant cost elements of a typical clinical study budget and breaks it down line by line so you can maximise your cost savings when you conduct a […]

Download the white paper to hear from leading industry experts in this emerging field who discuss: Challenges related to antigen and adjuvant selection Vaccine design Immune response improvement Future treatment options

An in vivo CRS Evaluation Study in humanised mouse models can deliver fast, reproducible, and translatable data about drug safety in just two weeks. A humanised mouse platform offers the unique ability to preclinically analyse a fully systemic response that involves human immune cells and surrounding tissues. Furthermore, the platform also allows for efficacy testing […]

Assessing the safety and efficacy of biotherapeutics is imperative during the drug-development process. In particular, pharmacokinetic (PK) and anti-drug antibody (ADA) assays are conducted to study and evaluate new drug candidates and biosimilars. For PK/ADA assays, anti-idiotype antibodies (Anti-IDs) are powerful tools to measure the concentration of antibody drugs in patient samples and serve as […]

Monitoring wastewater for SARS-CoV-2 – or Coronavirus as it is more commonly known – can be a valuable data resource for an effective Covid-19 management. However, there are several challenges involved in detecting biological parameters in wastewater. Fortunately, there are also several solutions available to overcome them. Wastewater can be a carrier medium of SARS-CoV- […]

Flow cytometry is a powerful tool allowing you to detect, measure, and quantify single cells or particles in suspension as they pass through a laser. However, to produce impactful results, experiments must be designed with care. This guide takes you through the fundamentals of flow cytometry, provides useful practical advice to optimise your experiments and […]

Clinical trials continue to determine whether therapeutic modulation of kinases can be used to suppress the immune system in autoimmune diseases or stimulate for antiviral and cancer immunotherapy. The discovery and characterisation of small molecule modulators have aided these efforts.   The Transcreener ADP² Kinase Assay meets this need as it relies on direct ADP detection to measure the activity […]

SAMDI Tech’s radioactivity assays overcome key challenges in drug discovery by offering key solutions, including: Detecting low amounts of product with sensitive assays Generating data rapidly with high-throughput, 384-well capabilities Characterising potent inhibitors by benefiting from lower enzyme concentrations In this free to download TechNote, learn how SAMDI Tech’s radioactivity assay characterised low turnover methyltransferase […]

In immunoassays-based research, immunodiagnostics, as well as immunotherapy, one of the highly critical aspect of antibodies is their reproducible performance. Antibody reproducibility is driven by their specificity and several other factors ranging from antibody design to target validation. This NEW eBook Antibody Production gives you an overview of the antibody’s life cycle by covering the following sub-topics: […]

Discover how process optimisation utilising automated synthetic biology solutions can remove the antibody sequence cloning bottleneck that divides high-content lead identification and downstream high throughput characterisation. If your work involves antibody discovery or process improvement in recombinant cloning don’t miss this whitepaper illustrating how Codex DNA’s synthetic biology solutions can accelerate antibody discovery workflows. In […]