Boost your drug discovery with 3D spheroid models and live-cell analysis – perfect for screening thousands of compounds! Download the App Note to learn: How to capture dynamic cellular changes in real time How to understand the advantages of 3D assays over traditional 2D models About advanced imaging and analysis… Read More
Boost your drug discovery with 3D spheroid models and live-cell analysis – perfect for screening thousands of compounds! Download the App Note to learn: How to capture dynamic cellular changes in real time How to understand the advantages of 3D assays over traditional 2D models About advanced imaging and analysis… Read More
Looking to transition to fluorescent western blotting or wanting to maximise the output of your multiplex western blotting experiment? These two app notes cover all the essentials and more: Best practices Troubleshooting tips Easy to follow protocols Brought to you by Copyright 2025 Drug Discovery World. Read More
Discover how the Agilent BioTek Cytation cell imaging multimode reader and ViQi’s AVIA provide a powerful, integrated solution for viral infectivity analysis. Download the application note to explore how this innovative approach offers key advantages over traditional assays, including: High-throughput, cost-effective analysis: AVIA minimizes reagent use, incubation time, and replicate needs,… Read More
See how Cerno MassWorks™ delivers sub-millidalton mass accuracy and >99% spectral accuracy—enabling formula ID on standard LC/MS systems. This detailed application note walks you through the results, method, and impact. Confidently identify unknowns using spectral accuracy Extend the power of your existing single quad LC/MS Eliminate reliance… Read More
Scale Bio’s ScalePlex technology and Single Cell RNA Sequencing Kit v1.1 are revolutionising drug discovery by making large-scale single cell sample and condition screening possible. Libraries from 384 drug conditions were prepared in just 1.5 days 90% reduction in processing time >80% cell recovery rate and >3000 unique transcripts per… Read More
Discover Cyto-Mine® Chroma and picodroplet technology for advanced single-cell analysis: Multiplexing: Simultaneously detect and isolate rare secreting cells using secreted and cellular markers. Ultra-High-Throughput: Efficiently process and sort millions of cells with high accuracy. Cell viability: Maintain high viability and accuracy using complex assays. Download the application note to transform… Read More
With the use of innovative solubilization approaches, such as synthetic copolymers, structural biologists can efficiently create soluble membrane proteins optimized for cryo-EM workflows. In this application note, learn how to screen for the optimal copolymers using a combination of parameters from the Prometheus Panta instrument for stability characterization of membrane proteins. Read More
Download this application note to learn more about: Co-culture methods for ioMicroglia with wild type and disease model ioGlutamatergic Neurons. Assay optimisation for a live cell in vitro neuronal activity assay. Solutions for visualisation and quantification of changes in co-culture health, morphology, function and marker expression. … Read More
Download bit.bio’s application note to learn more about: Functional characterisation of human iPSC-derived ALS disease models using high throughput MEA. Phenotypic data showing reduced neuronal activity and network formation in ALS disease models. A genetically matched system in ioGlutamatergic Neurons that can be used to identify, measure and rescue disease-related… Read More
Gain critical insights from benchmarking data and steps taken by Pfizer’s R&D team to adopt automation into tissue workflows for downstream LC-MS analysis: ~ 40% increase in throughput Increase working sample range ~ 5-fold compared to traditional methods Significant reduction in analyst workload Lower risk of operator error or variability… Read More
As the demand for mRNA-based therapies surges, the efficiency of the production process becomes paramount. Binding conditions in affinity chromatography need to be optimised, to keep up with the increasing efficiency of IVT reactions, and to deliver high yields and purities. In this application note, we demonstrate… Read More