Key takeaways: Boost Workflow Efficiency: Discover how end-to-end testing can enhance the efficiency of your monoclonal antibody production process. Ensure Compliance: Learn about the importance of accurate and precise testing at various production stages to meet or exceed regulatory guidelines. Guarantee Quality: Understand how proper testing ensures product safety, quality, and potency throughout… Read More
In this Case Study, InSphero, a Swiss-based company specializing in 3D in vitro cell models and cell culture tools for drug discovery, describes: The advantages of 3D in vitro cell models for drug discovery The automation of the production of 3D in vitro cell models via InSphero’s Akura™ technology The… Read More
It is crucial for the long-term viability of cell and gene therapy development programs that early-phase researchers are aware of how the methods and materials they select can impact the program’s future success, especially in terms of regulatory approval, cost, and timeframe. With 40-50% of CGT programs that enter Phase… Read More
In the tenth eBook of the Hamilton series, “Cell-Based High-Throughput Screening”, we discuss: Cell-based models used in research – Pros and Cons. Challenges of cell-based high-throughput screening. Hamilton software and hardware tools for cell-based assays. Brought to you by … Read More
Organ-Chips have seen significant growth in adoption over the past few years. A blinded survey across industry and academia found: 97% of experienced Organ-Chip users say the technology is more predictive than conventional in vitro models. 70% of experienced Organ-Chip users describe the technology as more predictive than… Read More
Lipid nanoparticles (LNPs) have great potential to revolutionize the development of nucleic acid therapies. Download the guide to learn more about: The basic concepts and components of lipid-based drug delivery systems Important considerations for LNP design, stability, and storage Techniques for LNP preparation, characterization, and functional assessment… Read More
Gain critical insights from benchmarking data and steps taken by Pfizer’s R&D team to adopt automation into tissue workflows for downstream LC-MS analysis: ~ 40% increase in throughput Increase working sample range ~ 5-fold compared to traditional methods Significant reduction in analyst workload Lower risk of operator error or variability… Read More
This paper discusses the challenges drug developers face when transitioning from preclinical discovery to clinical trials and proposes expanding the drug development toolbox with humanised mouse models. Download the latest whitepaper to learn more about: The importance of selecting appropriate starting doses in clinical trials. Why humanised mice… Read More
Download this interactive infographic to: Discover ways to navigate your contamination, compliance, reproducibility, monitoring and scalability challenges Identify which critical factors and equipment you should consider to help succeed in a GMP environment Unlock access to an extensive collection of helpful resources… Read More
This whitepaper, Fuelling the future: Precision medicine innovation and the role of ecosystems, examines how the future of drug discovery and precision medicine can be enhanced by life science ecosystems such as those created by the UK’s leading property developer to the science and technology sectors, Bruntwood… Read More
In this case study, hear from Elise Malavasi, Ph.D., a Principal Scientist at leading contract research organisation Concept Life Sciences. The interview highlights their need to develop assays that are amenable to long term use to support their clients with drug development, and how bit.bio’s deterministically programmed ioMicroglia have helped… Read More
Learn about the key principles, methodologies and regulatory requirements of drug stability testing with our recently developed eBook: Drug Stability Testing 101. This eBook has been prepared by scientists and industry professionals at Thermo Fisher Scientific to provide you with valuable insights and practical knowledge to help you optimise… Read More
Read this whitepaper to: Gain insights into the diverse and complex structures of new molecular formats, often encompassing multiple chains and multiple domains Understand the unique challenges faced during the process development and manufacture of these advanced proteins Explore how characterising these products and developing robust manufacturing processes can… Read More
Understanding the mechanisms of disease requires complex data ranging from genomic data through to transcriptomics, epigenetics and proteomics. Legacy multiomic approaches require multiple platforms and complex processes, which are incompatible with disease research that utilises scarce tissue samples. Download the brochure to learn how multiomic nanopore sequencing can… Read More
As the demand for mRNA-based therapies surges, the efficiency of the production process becomes paramount. Binding conditions in affinity chromatography need to be optimised, to keep up with the increasing efficiency of IVT reactions, and to deliver high yields and purities. In this application note, we demonstrate… Read More
Discover a clinically predictive and reproducible platform developed by The Jackson Laboratory for simultaneous efficacy and safety assessment. This platform identifies patient-therapy combinations at risk of developing severe inflammatory syndrome, a potentially fatal complication. Optimise the safety profiles of your immunomodulatory therapeutics before first-in-human trials by leveraging this platform. In… Read More
