Resources

ACROBiosystems DDW white paper
Whitepaper

Diving deep into cell therapy: An industry perspective

Cell therapy research has never been more exciting with all of the research ongoing. Learn more about the trends, insights, and perspectives from ACROBiosystems as a manufacturer of cell therapy reagents, including topics like: CAR-NK research Developing new CAR constructs Evaluation CAR expression detection Role of GMP Manufacturing in cell therapy

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eBook

Riding the mRNA highway: development, manufacturing, and beyond

Download this eBook to learn more about process development and manufacturing in the mRNA space to enable successful scale-ups of mRNA production for therapeutic applications. Topics covered in the eBook include: Expert views on mRNA development and manufacturing Advantages of mRNA processes compared to traditional vaccine manufacturing Best practices for scale up of in vitro […]

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Whitepaper

From bench to billions: A guide to facilitating scale-up of adherent cultures for cell and gene therapies

Given the potential of emerging advanced therapies, market demand is likely to continue to grow. Generating the required quantity of cells efficiently becomes even more challenging when the cells of interest are attachment-dependent, such as induced pluripotent stem cells (iPSCs). The choice of cell culture platform will have significant operational and commercial impacts. Download this […]

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Whitepaper

Trends in precision medicine: Cancer

This is an extraordinarily exciting time to be involved in precision medicine for cancer. This new whitepaper reviews some of the topics and trends in this emerging research area, including: 3D cultures: Spheroids and organoids Organoids in cancer research Tumour microenvironments Organ-on-a-chip and body-on-a-chip 3D bioprinting

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App Note

Characterising the phenotype of an isogenic, human iPSC-derived Huntington’s disease model by MEA

Currently, no effective cure or treatment for Huntington’s disease exists. To accelerate Huntington’s disease research and drug discovery, researchers need access to physiologically relevant human disease models that recapitulate patient phenotypes, in combination with more advanced methods to understand the underlying mechanisms of the disease. In this App Note you will learn: How Charles River […]

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Eurofins Guide
Latest Guide

Hit-finding strategies for potent and specific molecules

Download the guide for hit-finding tools that will accelerate your hit to lead and lead optimisation programs for CNS, metabolic, oncology and other therapeutic areas. Synthetic, medicinal, and computational chemistry capabilities along with in house available diversity and focused libraries Small molecule and biologics targeted screening for GPCRs, kinases, ion channels, interleukins, checkpoints, novel targets […]

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Whitepaper

High throughput, multi-parametric analysis accelerates antibody discovery workflows

In this whitepaper, we present the unique benefits of the high-throughput iQue®Advanced Flow Cytometry Platform, combined with built-in, visual-based iQue Forecyt®software, in the antibody discovery workflow. Learn analysis details of: Antibody Binding Antibody Internalisation and Viability ADCP Measurement in Adherent Cells ADCP Measurement in Suspension Cells Quantification of NK Cell-Mediated ADCC Antibody-Mediated T Cell Activation

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Whitepaper

Electroporation Made Easy for Hard-to-Transfect Cells

Download the latest Mirus Bio whitepaper to learn about: The differences between gene delivery methods (electroporation, chemical transfection and viral transduction). Optimising electroporation with the Ingenio(R) EZporator(R) Electroporation System. Electroporate multiple cell types with high efficiency and viability. Deliver different molecular cargo.

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App Note: Rapid Development of Automated Sars-CoV-2 Clinical Diagnostics
App Note

Rapid development of automated Sars-CoV-2 clinical diagnostics

Download the App Note to learn about: How to create and share an automated workflow for rapid development and validation of SARS-CoV-2 clinical diagnostics. The highly scalable liquid handling platform, CyBio FeliX for clinical diagnostics – it provides magnetic bead-based nucleic acid extraction, eliminating laborious and time-consuming column-based binding and spinning steps. Automating your diagnostic […]

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eBook cover
eBook

Efficiently develop antibody-based therapeutics

In the Quality by Design (QbD) approach to antibody-based therapeutics development, stability characterisation —the probability of a protein unfolding or denaturing— is performed to ensure that structure and function are preserved throughout development and manufacturing.  Antibodies are affected by many factors along their journey to become therapeutics. Stability characterisation assays are therefore pivotal to determine […]

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App Note

Afucosylated mAb expression benefits therapeutic antibody efficacy

Currently, at least 35 glycoengineered antibodies, with their Fc fucose partially or entirely removed, have been investigated in animal models or clinical trials. The absence of fucose on the Fc N-glycan increases IgG1 Fc binding affinity to the FcγRIIIa on immune effector cells like natural killer cells. It results in increased antibody-dependent cellular cytotoxicity (ADCC). […]

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Whitepaper

Read the Top Five Benefits of a Cloud ELN

As experimental data becomes bigger and more complex, scientists are challenged to make discoveries faster, consistently document and analyse their work, and easily collaborate across an organisation and with external partners. Electronic lab notebooks (ELN) provide access to all collaborators 24/7, wherever they are and whether they are employees or at contract organisations. If an […]

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Whitepaper

The latest MHC class I & II deficient in vivo platform humanised with PBMCs

This whitepaper, brought to you by The Jackson Laboratory will teach: The benefits of the JAX NSGTM-MHC I/II KO mouse platform humanised with pre-characterised PBMCs How this platform can support a wide range of immunological studies, especially those containing T cells responses The versatility of this platform to various research disciplines

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App Note

High throughput MALDI workflow with automated liquid handling

Download this App Note from Analytik Jena to learn about: Detection of lipid changes in microglia cells in generating therapeutic approach towards neuroinflammation diseases Application of label-free matrix-assisted laser desorption/ionisation (MALDI) MS cell fingerprinting workflows or cellular assays capable of characterising drug off-target responses with high throughput sample preparation done by Cybio FeliX Workflows to investigate […]

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Latest Guide

A life scientist’s how-to guide for organoids

Learn best practices to consider for organoid work, as well as how to use Corning Matrigel matrix and other products to support research. Organoids have gained popularity over the years due to their ability to self-organise into “mini-organs” capable of recapitulating their respective organ-specific functions. Products such as Corning Matrigel matrix can help streamline workflows for […]

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App Note

App Note – Learn about gene modification for cell therapy applications

Download this App Note from Thermo Fisher Scientific to discover an electroporation system that can: Meet requirements for commercial manufacturing processes Be integrated with a range of products and tools designed for use in cell therapy manufacturing Optimise the cell engineering step of your manufacturing process  

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