Taconic Biosciences, providers of animal model solutions for drug discovery, has launched a new Covid-19 mouse model. This human ACE2 (hACE2) transgenic mouse expands Taconic’s Covid-19 research toolkit. In October 2020, Taconic launched its first hACE2 model. The AC70 mouse experiences a lethal response to infection by SARS-CoV-2, the virus… Read More
China has reformed its regulatory system in recent years to include various fast-track programs similar to the US, EU and Japan to incentivise the development of drugs for unmet medical needs and serious conditions. However, only a few companies based outside of China have been granted priority review status by… Read More
The UK Country Manager of Pfizer, Ben Osborn, has been appointed as the new President of the Association of the British Pharmaceutical Industry (ABPI). Pinder Sahota, General Manager of Novo Nordisk, has been appointed as Vice President. Osborn will take over from Hasseb Ahmad and will lead on overseeing… Read More
By Erik Steinfelder, Biobanking Market Development Director at Thermo Fisher Scientific From hidden repositories, secreted deep in the basements of universities and hospitals, to the emergence of collaborative powerhouses driving ground-breaking therapies, biobanks have come a long way in the past 30 years. Biobanks were originally created as vast repositories… Read More
Oxford Immunotec’s T-SPOT Discovery SARS-CoV-2 kit will be used for T cell testing in a study being carried out in collaboration with researchers at the University of Leicester. The DIRECT study (Determining the Immune Response in Ethnic minority healthcare workers to Covid-19 infecTion) is recruiting healthcare workers in Leicester for… Read More
Tiny 3-D models that mimic vital aspects of the human nervous system have been developed in a step that could accelerate drug research for neurological conditions such as multiple sclerosis (MS). The millimetre-wide models – created using stem cells from human skin samples – will be… Read More
Scientists have revealed how an antibiotic of ‘last resort’ kills bacteria. The findings, from Imperial College London and the University of Texas, may also reveal a potential way to make the antibiotic more powerful. The antibiotic colistin has become a last resort treatment for infections caused by superbugs. However, despite… Read More
Sophie Lutter, OXGENE, looks at the important role antibody therapeutics have to play and how, as the world has looked for Covid-19 treatments in the last year, their significance has been noted. As the world continues to adjust and respond to the impact of the Covid-19 pandemic, the race… Read More
Adverum Biotechnologies has announced a Suspected Unexpected Serious Adverse Reaction (SUSAR) of hypotony (clinically-relevant decrease in ocular pressure) in its Infinity clinical trial evaluating ADVM-022 gene therapy for the treatment of diabetic macular edema (DME). This event occurred 30 weeks after randomisation in one patient treated with a single intravitreal… Read More
The latest DDW Sponsored Sitting Down With podcast features Anders Mälarstig, Director of Human Genetics, Pfizer. In this podcast he outlines the role of pQTLs in the drug discovery process and the growing importance of proteogenomics Mälarstig is currently responsible for developing and applying strategies for new drug targets and… Read More
The latest DDW Sponsored Sitting Down With podcast features Raj Indupuri, CEO of eClinical Solutions, and he talks to us about clinical trials. Listen to this podcast to find out why Indupuri believes ‘data is the new fuel that will drive human progress’, the effect of Covid-19 on clinical trials… Read More
The biggest constraint in discovering new antibodies for immunotherapy is constructing the underlying DNA sequence, says Dr. Aaron Sato, CSO of Twist Bioscience. Inside the human body, the immune system generates antibodies that can target just about any foreign molecule. It does so through DNA recombination and somatic hypermutation –… Read More
A study has found that a single dose of vaccine boosts protection against SARS-CoV-2 coronavirus variants, but only in those with previous Covid-19. In those who have not previously been infected and have so far only received one dose of vaccine, the immune response to variants of concern… Read More
Awakn Life Sciences, a biotechnology company focused on addiction, has initiated a new chemical entity (NCE) development programme to strengthen its pipeline for the treatment of a broad range of addictions. The company has also announced the appointment of Evotec as its NCE research partner and the selection of… Read More
Sygnature Discovery, an integrated discovery and pre-clinical solutions provider, has a new office in South San Francisco’s biotech hub at Oyster Point, where it says it can better serve current and future clients on the US west coast. The company has grown in the previous year, having recently expanded… Read More
The SLAS Europe 2021 Conference & Exhibition has announced it will be in an online format only. The event will include current research and collaboration, including more than 25 scientific talks across three educational tracks, 12 vendor tutorials and three keynotes, with added flexibility and opportunity to either watch content… Read More
