Author Archives: Megan Thomas

#Cell and gene therapy #Drug delivery #Drug development #Drug innovation #Life sciences

RoslinCT selected as vaccines and advanced therapies training centre

RoslinCT has been confirmed as a National Training Centre, part of the Department for Business, Energy & Industrial Strategy (BEIS) sponsored Advanced Therapies Skills Training Network (ATSTN) initiative. The organisation is the second National Training Centre confirmed as part of the ATSTN initiative, which was set up to develop vaccine… Read More

#News

#Cell and gene therapy #ELRIG #Events #Pharma

First ELRIG meeting on Cell & Gene Therapy

The ELRIG Cell & Gene Therapy meeting will be held virtually on May 18-19, 2021. This interactive two-day conference will host scientists from academia and industry to discuss current and future perspectives of cell and gene therapies. Cell and gene therapies are rapidly evolving, revealing many new therapeutic opportunities not… Read More

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#High throughput screening #Screening

The important integration of medicinal chemistry in Hit-to-Lead discovery

Listen to this article on the DDW Podcast: High-throughput screens are a recognised hit-finding process but the use of an integrated discipline approach is key to maximising the output from such a screening methodology. Ian Linney and Scott Maidment, Charles River, describe the value of integration of medicinal chemistry… Read More

#Editor's Choice #Exclusive Content #News

#Biopharmaceutical #Covid-19 #Life sciences #Pharmaceutical research #Vaccines

ABPI chief stresses importance of research investment

The Chief Executive of the UK’s Association of the British Pharmaceutical Industry (ABPI), Richard Torbett, has stressed the importance of investment in research in response to the Queen’s Speech delivery. “The response to the pandemic has shown just how critical the UK’s pharmaceutical industry is to our country’s future and… Read More

#News #Trending News

#Biotechnology #Data #Research

Vizgen advances spatial genomics research

Vizgen has released its first freely available dataset, the Vizgen MERFISH Mouse Brain Receptor Map. This is reportedly the first of a series of datasets that will be made available through the company’s new Data Release Program. The MERFISH release is said to mark the first time the research community… Read More

#News

#Alzheimer's #Biologics

C. elegans: a natural model for developing therapies to slow ageing

Ageing is a complex and heterogeneous process and is best studied using natural models of ageing in whole organisms and large test populations. C. elegans is a proven model in many fields of biology including ageing, where major breakthroughs have occurred by identifying mutants and interventions that increase… Read More

#News #Videos

#Data #Drug development #Drug repurposing #Drug research

In vitro drug interaction data critical in drug repurposing

Listen to this article on the DDW Podcast: In the wake of Covid-19 interest in repurposing a drug for a different indication to the one it was developed for has been high. Madison Knapp, Marketing Communications Specialist, and Dr. Brian Ogilvie, Vice President of Scientific Consulting, SEKISUI XenoTech offer… Read More

#Covid-19 #Editor's Choice #Exclusive Content #News #Opinion

#Clinical trial #Drug development #MS

‘Mega-trial’ for progressive multiple sclerosis (MS) to launch

Octopus, a world-first mega-trial for progressive multiple sclerosis (MS), will launch in the UK later in 2021, according to the MS Society. It is a clinical trial that is said will transform the way treatments for progressive MS are tested and could deliver new options up to three times faster. Read More

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#Clinical trial #Covid-19 #Data

Clinical trials impacted by slow enrolment

The surge in new variants for Covid-19 and an increase in subsequent cases is continuing to have an impact on clinical trials, while still allowing them to resume. The total number of disrupted trials has levelled off, but the number of clinical trials that have resumed continues to rise, although… Read More

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#Biologics / Biotechnology #Cell sequencing #DNA #Drug development #Drug discovery #Genome editing #Genome sequencing #Life sciences #Sequencing #Synthetic biology

The new synthesis: How synthetic DNA technology is changing drug discovery

Listen to this article on the DDW Podcast: Dr Tim Brears, CEO, Evonetix and Dr Raquel Sanches-Kuiper, Director of Biology, Evonetix explore applications of synthetic DNA in drug discovery and development, the benefits and limitations of current methods, and the opportunities offered by emerging DNA synthesis technologies. On 16… Read More

#Editor's Choice #Exclusive Content #News #Opinion

#Cancer research #Clinical trial

Lytix Biopharma announces positive Phase I data for LTX-315

Lytix Biopharma has announced promising full data results from a Phase I study of its lead candidate LTX-315 lysing solid tumours, which have been published in Clinical Cancer Research. The study was an open-label multicentre study of LTX-315 with multiple intralesional injections in patients with solid tumours for whom alternative… Read More

#Cancer Research #News

#Cancer #Cancer research #Drug delivery #Drug innovation #London Cancer Hub #Pharmaceuticals

Global hub for cancer research, treatment and commercial enterprise

Andy Carr, Business Development Manager at The Institute of Cancer Research, London, introduces the new Innovation Gateway at The London Cancer Hub in Sutton, south London, to DDW’s Megan Thomas. MT: I understand the establishment of the Innovation Gateway is underway. What is the progress and when is it due… Read More

#Cancer Research #Editor's Choice #Exclusive Content #News

#AstraZeneca #Biotherapeutics #Drug discovery #Immuno-oncology

Biotech collaboration to accelerate prostate cancer research

Alchemab has collaborated with AstraZeneca to work on a proof-of-concept study to build understanding of the fundamental biology of prostate cancer. Under the agreement, Alchemab’s novel drug discovery platform will be used as a diagnostic tool through the identification of disease biomarkers with potential to inform the development of novel… Read More

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#Biotechnology #Drug development #FDA #Research

The FDA expands lung-on-a-chip collaboration with CN Bio

The US. Food and Drug Administration (FDA) has extended its research collaboration with CN Bio for a further three years. The scope of the research carried out with the FDA’s Center for Drug Evaluation and Research (CDER) has now been broadened to include the exploration of CN Bio’s lung-on-a-chip using… Read More

#News

#Biotherapeutics #Cancer research #Drug development #Immuno-oncology #Pharmaceutical

Janssen seeks approval for refractory multiple myeloma drug

The Janssen Pharmaceutical Companies of Johnson & Johnson has submitted a Marketing Authorisation Application (MAA) to the European Medicines Agency (EMA) seeking approval of cilta-cel, an investigational B cell maturation antigen (BCMA)-directed chimeric antigen receptor T cell (CAR-T) therapy, for the treatment of patients with relapsed and/or refractory multiple myeloma. Read More

#Cancer Research #News

#Covid-19 #Drug delivery #Immunology / Virology & Vaccines #Moderna #Vaccines

500 million Covid-19 vaccine doses delivered to lowest income countries

Moderna has announced an agreement with Gavi, the Vaccine Alliance to supply up to 500 million doses of the Covid-19 Vaccine Moderna, including an initial 34 million doses to be delivered in the fourth quarter of 2021. Through this agreement, on behalf of the COVAX Facility, Gavi also retains… Read More

#Covid-19 #News