Biosciences

Metrion Biosciences, a specialist ion channel contract research and drug discovery company, and The KCNC1 Foundation, a not-for-profit organisation focused on the development of a treatment for an ultra-rare genetic disorder, have entered a collaboration to progress a hit identification research project for small molecule modulators of the potassium ion channel Kv3.1, targeting KCNC1-related disorders […]

Ochre Bio, a company developing therapies for liver health challenges, has closed $30 million in Series A financing, which will be used to translate the insights from their discovery research into RNA-based drug candidates, and then test these in human livers at their recently launched ‘Liver ICUs’ across the US.   Employing a deep phenotyping […]

Open Cell, a ‘hotel for scientists’ in London, UK, provides a cluster of small labs within a large shipping container facility, that are available for short-term rental by biotech startups with a range of shared services and facilities. As well as private labs, the facilities provide access to equipment worth millions of pounds for just […]

The latest DDW Sitting Down With sponsored podcast features Dominque Bröhl and Evert-Jan Uringa, Scientific Program Managers at Taconic Biosciences, who discuss how mouse model generation can be accelerated without any loss of quality. They offer insight into the latest developments, innovation and challenges in mouse model generation, how timelines can be accelerated without compromising […]

Alamar Biosciences, a proteomics platform, and Abcam, innovators in life sciences research tools, have partnered to further their understanding of the human proteome.  Proteomics  The field of proteomic analysis is in the spotlight. Its advance not only enhances the understanding of fundamental biology, but also sheds light on the status of human health and disease. […]

Anticancer Bioscience, a company developing synthetic lethal approaches to precision oncology, have relocated to Tianfu International Biotown, in Chengdu, China, to accommodate its growth and expansion, and on the back of its recent financing. Biotown is considered the premier biotech research park in Chengdu, the capital of Sichuan province.  The facility  The new facility is three times larger […]

Sixfold Bioscience (Sixfold), a company using computation and advanced chemistry to design RNA therapeutic delivery systems, has raised $10.5 million in its seed funding round, which will support the continued development of the company’s Mergo RNA therapeutics delivery platform.  Investors   Investors in the seed round included Cantos Ventures, Y Combinator, Lombard Street Ventures and Pi Campus, as […]

Neurocrine Biosciences and Sosei Group Corporation have collaborated to develop novel muscarinic receptor agonists, which Neurocrine Biosciences intends to study in the treatment for schizophrenia, dementia and other neuropsychiatric disorders.  The agreement terms  Under the terms of the agreement, Neurocrine Biosciences gains development and commercialisation rights to a broad portfolio of novel clinical and preclinical subtype-selective muscarinic […]

Twist Bioscience has acquired Abveris, which will offer Twist comprehensive antibody discovery and characterisation services using its DiversimAb family of hyperimmune mouse models, the output of which can be humanised using the Twist antibody optimisation solution to develop biologics for rapid clinical advancement.   Emily Leproust, CEO and co-founder of Twist Bioscience, believes that the addition of the Abveris discovery platform is a “natural fit” with Twist, as […]

Michael-John O’Connor, Director of Biochemical Services at BioPharmaSpec, discusses analysing biosimilars, glycosylated mAbs and PEGylated proteins with Lu Rahman.  LR: Outline the importance of bio-molecules in drug discovery. What is their potential within therapeutic development?    MJOC: The FDA’s recent approval of Biocon’s Semglee (long acting Insulin glargine) is the first example of an interchangeable biosimilar that can be substituted for its reference medicinal product, […]

RareCan has received approval from the NHS Research Ethics Committee to establish its BioResource at Newcastle University, which will store tissue samples from rare cancer patients collected during surgery, will be accessible to scientists around the globe undertaking research into the prevention, diagnosis or treatment of rare cancers. This reduces the time taken to provide samples […]

Culture Biosciences has selected Scispot.io to digitise and automate its media preparation workflows while maintaining an audit trail.   Connecting data from multiple sources with Scispot, Culture Bioscience aims to reduce its experiment failure rate and improve the scientific output.  “Scispot is designed for mapping custom biomanufacturing workflows developed by Culture Biosciences. Using Scispot, Culture is increasing its experiment success rate and optimising the usage of chemicals […]

Crown Bioscience has launched its ‘3D Ex Vivo Patient Tissue Platform’ which, using freshly collected patient tumour material, can accurately measure oncology and immuno-oncology drug-induced tumour killing and endogenous immune cell proliferation in a high throughput format.   Researchers presented data on the new platform at 2021’s AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, which took place virtually on October 7-10, 2021.  […]

The brain: how much don’t we know? Dr Jim Ross, Chief Technology Officer and Co-founder of Axion BioSystems, asks and discusses the answers to this question. Epilepsy, amyotrophic lateral sclerosis (ALS), Alzheimer’s — we hear these brain disease names all the time, but it feels like we never hear about effective treatments or cures. While medical advances are gradually helping researchers understand the brain and address neurological […]

Nottingham, UK-based contract research organisation (CRO) Cellomatics Biosciences has reported year-on-year organic revenue growth of 30% since its inception in 2015, as demand for its preclinical and early discovery phase laboratory services and expertise continues to increase.   Based at BioCity Nottingham, Cellomatics is a specialist preclinical CRO with expertise in five main therapeutic areas: oncology, immuno-oncology, immunology, inflammation and respiratory. Despite the challenges […]

In this video, Dr Gary Allenby, CEO Aurelia Bioscience, describes a scientific poster on ‘Protein-protein Interactions Using NanoBRET Technology’. Historically, only solution-based assays were used to screen compounds in PPI, but a more physiological approach is to examine the interaction in living cells. However, there are very few commercially available technologies that can actually do […]