Protein degradation

A new webinar ‘Selective degradation of cancer target WDR5 — Evaluation of PROTACs binary and ternary affinities with Spectral Shift‘, brought to you by NanoTemper, is now available to watch on-demand. As more and more R&D pipelines include PROTAC candidates — the race to bring successful and efficient protein degraders to the clinic is on. […]

As more and more R&D pipelines include PROTAC candidates — the race to bring successful and efficient protein degraders to the clinic is on. These targets present challenges in the biophysical characterisation of binary and ternary complexes, making developing effective degraders complicated. Watch this on-demand webinar to learn: How Spectral Shift technology lets you take […]

A new Guide is now available for download from NanoTemper. The development of a successful PROTAC candidate requires overcoming challenges at each stage of development. Read this guide to learn about common roadblocks, technologies to overcome them, and how to ensure you’re on the right track to building an efficient protein degrader. Download this guide […]

The development of a successful PROTAC candidate requires overcoming challenges at each stage of development. Read this guide to learn about common roadblocks, technologies to overcome them, and how to ensure you’re on the right track to building an efficient protein degrader. Download this guide to learn about: The most common roadblocks at key stages […]

NanoTemper outlines four questions to ask yourself to ensure you’re on the right track. Working in PROTACs, you’re tasked with the most challenging targets — that aim to address intractable diseases such as cancer, Alzheimer’s, or Parkinson’s disease. Despite the impressive promise of PROTACs, you still have to overcome many hurdles in order to work […]