Dr Todd Dickinson, CEO, Stellaromics on 3D spatial biology and functional genomics. Understanding how genes are regulated and expressed in complex tissue environments is fundamental to modern drug discovery. Traditionally, researchers have relied on 2D spatial genomics methods, analysing thin slices of tissue on a single plane to study gene… Read More
Dr Thomas Ybert, Co-founder and Chief Scientific Officer at DNA Script, describes how recent advancements in enzymatic DNA synthesis are unlocking previously inaccessible regions of the genome. Synthetic nucleic acids are foundational tools in biological research and therapeutic development, essential for applications ranging from gene synthesis to mRNA vaccine templates. Read More
DDW Editor Reece Armstrong looks at the challenges and opportunities for biobanking in drug discovery. The biobanking market was worth $81.29 billion in 2024 according to GrandView Research1 and is expected to reach $126.7 billion by 2030. A legacy sector for life sciences, biobanks have acted as repositories for research… Read More
Scientists have discovered that people diagnosed with ME/CFS have significant differences in their DNA, offering the first robust evidence that genes contribute to a person’s chance of developing the disease. Initial findings have uncovered eight areas of genetic code in people with ME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome)… Read More
DDW Editor Reece Armstrong speaks to Josh Mandel-Brehm, CEO of CAMP4 Therapeutics, about challenges in the discovery and development of RNA therapeutics. RA: Why has regulatory RNA historically not been exploited as a therapeutic target? JMB: Historically, RNA has been viewed primarily as a messenger — a passive intermediary between… Read More
A team at Standford have created CRISPR-GPT, a large language model (LLM) agent system to automate and enhance CRISPR-based gene-editing design and data analysis. CRISPR-GPT leverages the reasoning capabilities of LLMs for complex task decomposition, decision-making and interactive human–artificial intelligence (AI) collaboration. The system incorporates… Read More
DDW’s Megan Thomas speaks with Dr Madhuri Hegde, Senior Vice President and Chief Scientific Officer at Revvity Omics, about how the integration of multiomics is advancing companion diagnostics and personalised medicine. MT: How is the integration of multiomics transforming the landscape of companion diagnostics? MH: We see multiomics as a… Read More
This paid-for advertorial by Sampled appeared in DDW Volume 26 – Issue 3, Summer 2025 Read the digital issue Biobanking optimises sample storage, processing, transport, and access to deliver the promises of medical innovation. Biobanks are designed to meet the demands of new medical technologies by offering the scale for… Read More
The DDW Summer issue is available to read now. It features in-depth articles on the technologies and advancements driving genomics drug discovery, how supercomputing can drive neuroscience discoveries, and everything you need to know about spatial biology. Other features include: A market report on… Read More
For the first time, scientists have systematically studied the genetic effects of chemotherapy on healthy tissues. Researchers from the Wellcome Sanger Institute, the University of Cambridge, Cambridge University Hospitals NHS Foundation Trust (CUH) and their collaborators analysed blood cell genomes from 23 patients of all ages who… Read More
OutSee has secured £1.8 ($2.4) million in seed funding, led by Ahren Innovation Capital and with additional investment from Kadmos Capital, Empirical Ventures and Panacea Ventures. The funds will support OutSee through the next phase of its growth strategy, with a focus on expanding the company’s in-house target discovery programme… Read More
Biotechnology company Enhanced Genomics has announced a strategic partnership with The ALBORADA Drug Discovery Institute at the University of Cambridge. Funded by Alzheimer’s Research UK, The ALBORADA Drug Discovery Institute is developing the next generation of treatments for the diseases that cause dementia. The partnership… Read More
The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. This week’s round-up highlights the vital role of genetics in drug discovery, including new data… Read More
News round-up for 9-13 June by DDW Senior Digital Content Editor Diana Spencer. This week’s round-up highlights the vital role of genetics in drug discovery, including new data for an Alzheimer’s gene therapy, the discovery of a genetic target for rejuvenation therapies, and a 13-year follow up on… Read More
This is the latest episode of the free DDW narrated podcast, titled “Innovative uses for biomarkers in drug discovery”, which covers two articles written for DDW Volume 24 – Issue 4, Fall 2023. They are called: “How biomarkers can help discover new treatments for women’s health” and… Read More
Birmingham scientists have identified essential genetic code for a method called plasmid curing, which aims to ‘displace’ antibiotic resistance genes from bacteria. Plasmids play a crucial role in allowing bacteria to share beneficial genes rapidly in a changing environment, most concerningly when they carry genes conferring resistance… Read More
