Click chemistry

#Astex Pharmaceuticals #Bioorthogonal chemistry #Click chemistry #Cognitive impairment #Covid-19 #Drug discovery #Life sciences #Long Covid #Molecular Biology #Neuroscience #Public health

Podcast: Innovative approaches to improving drug discovery

This is the latest episode of the free DDW narrated podcast, titled “Innovative approaches to improving drug discovery”, which covers three articles written for DDW Volume 24 – Issue 2, Spring 2023 of DDW. They are called: Post-Covid cognitive impairment: a new target for drug development?, Sitting Down… Read More

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Click chemistry
#Acepodia #Bioorthogonal chemistry #CAR-T #Cell therapy #Click chemistry #Oncology #Phase I trial

First use of click chemistry in CAR-T cell therapy shows promise

Acepodia has announced promising preliminary data from its Phase I dose escalation clinical trial of ACE1831, an anti-CD20 antibody conjugated allogeneic gamma delta T cell therapy being evaluated in patients with non-Hodgkin’s lymphoma (NHL). One out of five patients demonstrated complete response (CR) and three out… Read More

#Cancer Research #News

Click chemistry
#Cancer research #Click chemistry #Immunotherapy #Oncology #Stanford University #University College London

Novel anti-cancer therapy created using click chemistry

A potent anti-cancer therapy has been created using Nobel prize-winning “click chemistry”, in a new study by University College London (UCL) and Stanford University researchers. The study, published in Nature Chemistry, opens up new possibilities for how cancer immunotherapies might be built in… Read More

#Cancer Research #News #Trending News

Chemistry
#Cancer research #Click chemistry #Johnson & Johnson #Oncology #Partnership #Shasqi

Partners will use click chemistry to create targeted cancer therapies

Biotech company Shasqi and Johnson & Johnson have entered into a research collaboration to develop new cancer therapies. Shasqi’s Click Activated Protodrugs Against Cancer (CAPAC) platform relies on chemistry for activation of drugs at the tumour. The platform is made up of a tumour-targeting agent and… Read More

#Cancer Research #News

Chemistry
#Bioorthogonal chemistry #Click chemistry #Drug discovery #Molecular Biology

The Nobel Prize winning power of click chemistry

Listen to this article on the DDW Podcast: José Mejía Oneto, PhD, Founder and CEO at Shasqi, discusses the potential of chemistry to engineer biology to improve the effectiveness of human therapeutics and revolutionise the treatment of disease. What if we could control… Read More

#Exclusive Content

#Biomarkers #Cancer research #Click chemistry #Covid-19 #Drug development #Drug discovery #Epstein-Barr virus #Monoclonal antibodies #mRNA #Oncology #Our Future Health #Pancreatic cancer

This week in drug discovery (24-28 October)

News round-up for 24-28 October by DDW Digital Content Editor Diana Spencer  Over the last seven days we’ve seen discoveries that could lead to new treatments for Covid-19, pancreatic cancer and Epstein-Barr virus, as well as the launch of the UK’s largest health research programme and the innovative application of… Read More

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Click chemistry
#Biomarkers #Bioorthogonal chemistry #Click chemistry #Genetic engineering #Proteins

‘Click’ chemistry used to tag proteins made by cancer cells 

A new method to study the proteins released by cells, which could lead to new biomarkers for diseases including cancer, has been developed by scientists at the Francis Crick Institute and Imperial College London.   Biomarkers are valuable tools in diagnosing disease or predicting treatment outcomes, but they are… Read More

#Cancer Research #News