Business

#Business #Gene editing #High throughput screening #Lead discovery #RNA #Screening

Horizon Discovery streamline CRISPR gene editing workflows

Horizon Discovery Group plc, a global leader in the application of gene editing and gene modulation technologies, today announced the addition of predesigned synthetic single guide RNA (sgRNA) to its product range. The sgRNAs, available individually or as library collections, expand the Company’s Edit-R gene engineering… Read More

#News

#Analysis #Assay development optimisation & technology #Business #Cellular assays #Microfluidics #Patent Law #System biology #Systems biology

Sphere Fluidics expands commercial operations with Pico-Surf

Sphere Fluidics expands commercial operations to increase supply of Pico-Surf surfactant for droplet microfluidics. Sphere Fluidics, a company commercializing single cell analysis systems underpinned by its patented picodroplet technology, today announced investment in the production and supply of its proprietary biocompatible surfactant, Pico-Surf™, for reliable and… Read More

#News

#Analysis #Business #Lead discovery #Mass spectrometry / NMR #Metabolomics #Protein chemistry / Proteomics #RNA #Therapeutics

Thermo Fisher to showcase new products at Virtual ASMS Event

Thermo Fisher Scientific will provide online programming and virtual exhibits to introduce scientists to a number of new products that build on its leading Orbitrap platform and expand research applications. The company said it will showcase its newest instruments, software and workflow solutions during a company-hosted virtual event, vLC-MS.com,… Read More

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#AI / data analytics / healthtech / informatics #Business #Drug discovery #Target validation

Thermo Fisher expands options for SampleManager LIMS

Thermo Fisher Scientific has expanded available options for SampleManager LIMS software, offering laboratories end-to-end support of the software deployment in the Amazon Web Services (AWS) Cloud. Under a contract agreement, Thermo Fisher will manage the process from installation and maintenance to backup and recovery. Labs will benefit from… Read More

#News

#Academic #Biologics / Biotechnology #Business #Cell culture #Cell therapy #Gene therapy #Microfluidics

Technology developed to rapidly scale up cell and gene therapy manufacture

Image: ThisisEngineering RAEng CPI, MicrofluidX and the Cell and Gene Therapy Catapult (CGT Catapult) have collaborated in a project to develop bioprocessing technology for the rapid scale-up of cell and gene therapies. The technology has the potential to overcome a major bottleneck in the development of these novel… Read More

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#Business #Drug development #Drug discovery #High Content Screening #Immunology #Immunology / Virology & Vaccines #Lead discovery #Oncology #Preclinical #Regulatory #Stem cells

Cancer Research UK collaborate to develop head and neck cancer vaccine

This a new clinical development partnership to progress a therapeutic DNA vaccine, TGL-100, into an early phase clinical trial targeting head and neck squamous cell carcinoma (HNSCC) HNSCC is the UK’s eighth most common cancer, but treatment options are limited and around 4,000 of those affected in the… Read More

#Cancer Research #News

#AI / data analytics / healthtech / informatics #Business #Computational chemistry #Drug development #Drug discovery #Drug targets #Gene therapy #Molecular medicine #Orphan drugs #Precision medicine

Centogene and Molecular Health collaborate to develop orphan drugs

Image: Fabio Centogene and Molecular Health, are to collaborate on the Real-life data and Innovative Bioinformatic Algorithms (RIBA) project, starting with epilepsy as the first indication. RIBA aims to foster a unique novel precision medicine environment to accelerate, de-risk, and improve the development of new orphan drugs based… Read More

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#Academic #Business #Cell therapy #Cellular assays #Clinical specialities #Drug development #Drug discovery #Enabling technologies #Genomics #High Content Screening #High throughput screening #Imaging #Lead discovery #Microfluidics #Screening #Stem cells #Target validation #Therapeutics #Translational #Translational chemistry

Drug target for aggressive breast cancer found

A team of British and American scientists has discovered a way to slow the growth of breast cancer stem cells in the lab. The study led by Dr Bruno Simões and Professor Rob Clarke from The University of Manchester could eventually lead to combination drug therapies on previously… Read More

#Cancer Research #News

#Academic #Business #Cellular & Molecular biology #Cellular assays #Clinical trials #Drug development #Drug discovery #Enabling technologies #Genomics #High Content Screening #High throughput screening #Imaging #Immunology / Virology & Vaccines #Microfluidics #Screening #Stem cells #Therapeutics #Translational #Translational chemistry

UK government advises drug companies to stockpile in case of Brexit disruption

Image: Joshua Coleman According to the Department of Health and Social Care (DHSC), pharmaceutical companies should stockpile six weeks’ worth of goods “to help ensure the continuity of supply of medical goods into and out of the UK”. In a letter to the industry Steve Oldfield, Chief Commercial Officer,… Read More

#Covid-19 #News

#Automation / robotics #Business #Drug discovery

SLAS2021 goes digital

Image: Rodion Kutsaev SLAS2021 will now be a fully digital experience as well as a celebration of 10 years of laboratory automation, scientific education and innovation. The event will be free for SLAS Premier Members and students with registration opening in October. Advantages of SLAS2021 Digital: More members of… Read More

#News

#Business #Clinical trials #Drug development #Drug discovery #Imaging #Immunology / Virology & Vaccines #Lead discovery #Regulatory #RNA

GSK and Sanofi to supply US government with 100 million doses of COVID-19 vaccine

Sanofi and GSK have announced a collaborative effort with the US government to accelerate the development and manufacturing of a COVID-19 recombinant protein-based vaccine. The vaccine candidate, developed by Sanofi in partnership with GSK, is based on the recombinant protein-based technology used by Sanofi to produce an influenza… Read More

#Covid-19 #News

#Business #Drug development #Drug discovery #Genetics / genomes #Immunology #Oncology #Therapeutics

Horizon Discovery licenses platform to TrueBinding for biotherapeutics development

TrueBinding, a biopharmaceutical company, has signed a set of commercial licenses for Horizon Discovery’s CHOSOURCE platform. TrueBinding will use the cGMP-compliant platform for the development and commercialisation of multiple biotherapeutic products for applications in immuno-oncology and other disease areas with great unmet medical need. Horizon’s CHOSOURCE platform includes a gene-edited… Read More

#News

#Academic #Biologics / Biotechnology #Business #Cellular assays #Clinical trials #Drug development #Drug discovery #Enabling technologies #Genomics #High Content Screening #High throughput screening #Imaging #Immunology #Microfluidics #Screening #Stem cells #Therapeutics #Translational #Translational chemistry

Just-Evotec Biologics to make monoclonal antibody products for COVID-19

Image: Ani Kolleshi The US Department of Defence (DOD) has awarded Evotec’s Seattle-based subsidiary, Just-Evotec Biologics a contract worth $18.2 million to develop monoclonal antibodies (mAbs) for treatment and/or prevention of COVID-19 Under the contract, Just–Evotec Biologics will design a manufacturing process for the production of Current Good… Read More

#Covid-19 #News

#Academic #Assay development optimisation & technology #Business #Cell therapy #Cellular assays #Chemical engineering #Clinical trials #Drug development #Drug discovery #Enabling technologies #Gene editing #Gene therapy #Genomics #High Content Screening #High throughput screening #Imaging #Lead discovery #Microfluidics #Oncology #RNA #Screening #Stem cells #Therapeutics #Toxicology #Translational #Translational chemistry

Merging two immunotherapies may be more effective treatment against some cancers

Some of the most promising advances in cancer treatment have centred on immunotherapies that rev up a patient’s immune system to attack cancer. However, immunotherapies don’t work in all patients, and researchers have been searching for ways to increase their effectiveness. Now, researchers at Washington University School of… Read More

#Cancer Research #News

#Analysis #Business #Cell therapy #Clinical trials #Drug development #Drug discovery #Gene therapy #High throughput screening #Imaging #Mass spectrometry / NMR #Microbiology #Screening #System biology #Target validation

Avacta updates on clinical validation of Adeptrix COVID-19 diagnostic test

Image: Pille-Riin Priske Avacta has begun work with the UK government’s CONDOR programme to evaluate and clinically validate the high throughput COVID-19 bead-assisted mass spectrometry (BAMS) laboratory assay developed with Adeptrix. The COVID-19 National Diagnostic Research and Evaluation Platform (CONDOR), recently funded by the National Institute for Health… Read More

#Covid-19 #News