Thermo Fisher Scientific will provide online programming and virtual exhibits to introduce scientists to a number of new products that build on its leading Orbitrap platform and expand research applications.
The company said it will showcase its newest instruments, software and workflow solutions during a company-hosted virtual event, vLC-MS.com, on May 26 -28, 2020, and at the American Society for Mass Spectrometry (ASMS) Reboot Program, on June 1 – 12, 2020. “The need for accelerated research has been heightened during the pandemic, and the public is expecting unprecedented progress from the scientific community”, said Dan Shine, Senior Vice President and President, Analytical Instruments. “A deeper analysis of proteins is critical to understanding disease, including novel viruses. New instruments, software and workflows can power discovery, improve productivity and enable breakthroughs across everything from small molecule studies to metaproteomics and biotherapeutics discovery”, he added.
Thermo Fisher Scientific said its new Thermo Scientific Orbitrap Exploris 240 mass spectrometer expands the proven Orbitrap Exploris platform and is designed to give scientists working in proteomics, metabolomics, biopharmaceutical characterisation and small-molecules the analytical performance required for research and high-throughput analyses. The new system is expected to advance discovery and identification with increased accuracy for confident scale-up, while providing operational simplicity and streamlining time-to-result. In addition, the new Thermo Scientific Orbitrap Exploris 120 mass spectrometer is said to deliver demonstrated qualitative and quantitative capabilities synonymous with Orbitrap high-resolution accurate-mass (HRAM) spectrometry, with internal calibration that assures consistent data quality and decision making. These newest systems extend the Thermo Scientific Orbitrap Exploris portfolio of HRAM systems, which were introduced in 2019 with the release of the new-generation Thermo Scientific Orbitrap Exploris 480 mass spectrometer.
Furthermore, the company’s Thermo Scientific Proteome Discoverer 2.5 software is said to provide high confidence during peptide identification, more accurate quantification and higher throughput data analysis for proteomics researchers. Deep learning-based prediction of tandem mass spectra, facilitated through a new collaboration with MSAID GmbH, a software company transforming proteomics through deep learning, allows more scientists to benefit from vast improvements in identification confidence and reproducibility. To further enhance characterisation of protein biotherapeutics and oligonucleotide therapeutics, biopharmaceutical laboratories now use the Thermo Scientific BioPharma Finder 4.0 software, which provides greater flexibility and customisation for this growing industry.
Thermo Fisher Scientific said its partnership with provider of sample preparation technologies for protein-based clinical research, Evosep, recently led to the launch of an automated ultra-high throughput plasma protein profiling platform, combing the power of the new Thermo Scientific Orbitrap Exploris 240 mass spectrometer with the Evosep One liquid chromatography solution. Also, the expanded collaboration with Biognosys, a developer of next-generation proteomics solutions, resulted in the development of data-independent acquisition mass spectrometry-based workflows and includes a novel FAIMS-DIA method that features the Thermo Scientific FAIMS Pro interface, which is said to improve selectivity, reproducibility and proteome coverage, as well as new methods that streamline discovery by combining Thermo Scientific SureQuant Targeted Assay Kits and the Biognosys PQ500 kit in a single workflow.
