Therapeutics

The American Association for Cancer Research (AACR) Annual Meeting is taking place at the Orange County Convention Center in Orlando, Florida from April 14-19, 2023. As the theme, Advancing the Frontiers of Cancer Science and Medicine, suggests, a number of announcements, results and presentations will take place at what is widely considered to be a […]

Granular Therapeutics, a UK-based biotech company specialising in precision biologic therapies for treating mast cell driven disorders, announced clinical candidate selection for its lead programme which has demonstrated promising results in initial preclinical studies.  Granular Therapeutics has now commenced proof-of-concept (POC) and IND-enabling studies as it prepares for clinical development.   Since starting work on these […]

Redx, a clinical-stage biotechnology company focused on discovering and developing novel, small molecule, highly targeted therapeutics for the treatment of cancer and fibrotic disease, has shared topline monotherapy data from the biliary tract cancer (BTC) module of the RXC004 PORCUPINE2 Phase II clinical trial programme. RXC004 is an orally active, once daily, porcupine inhibitor being […]

Today marks the start of SLAS2023 in San Diego. Over the last week, DDW’s Megan Thomas has narrated five articles from the SLAS2023 supplement as part of the DDW Events podcast series. Episodes include: A Welcome to SLAS 2023 Acquiring deeper insights and acceleration with AI Connecting lab automation to decision-making How machine learning and lab automation […]

Ahead of this year’s SLAS2023 conference in San Diego (which takes place 25 February – 1 March) DDW’s Megan Thomas narrates articles from the DDW SLAS2023 supplement as part of the DDW Events podcast series. This is episode four, How machine learning and lab automation are changing the future of protein therapeutics. In this article, […]

Ahead of this year’s SLAS2023 conference in San Diego (which takes place 25 February – 1 March) DDW’s Megan Thomas narrates articles from the DDW SLAS2023 supplement as part of the DDW Events podcast series. This is episode two, Acquiring deeper insights and acceleration with AI. At IBM Research, a group of scientists and researchers […]

This is the latest episode of the free narrated DDW podcast, “CROs and targeted protein degradation offer an exciting future”. It covers two articles written for Volume 23, Issue 1 – Winter 2021/22 of DDW. They are called “CROs: Drug discovery expertise on hand” and “Why the emergence of targeted protein degradation is so exciting”. […]

Moderna has become the newest member of the UK’s pharmaceutical industry body, the Association of the British Pharmaceutical Industry (ABPI), building on the long-term commitment by the American-based company to expand its footprint and investment in the UK.  Moderna, a biotechnology company pioneering messenger RNA (mRNA) therapeutics and vaccines, reportedly has ‘high ambitions’ for rapid […]

Metrion Biosciences, a specialist ion channel contract research and drug discovery company, and The KCNC1 Foundation, a not-for-profit organisation focused on the development of a treatment for an ultra-rare genetic disorder, have entered a collaboration to progress a hit identification research project for small molecule modulators of the potassium ion channel Kv3.1, targeting KCNC1-related disorders […]

This is the latest episode of the free DDW podcast, “Complex problems require complex solutions”. It covers two articles written for Volume 23, Issue 1 – Winter 2021/22 of DDW. They are called “How quantum computing can benefit drug discovery” and “Sitting down with Dr Michael Hayden from Prilenia Therapeutics”. In the first article, Brad […]