The regulation of cellular bioenergetics is recognised as a key driver of cancer cell proliferation. Identifying key pathways that modulate bioenergetic metabolism is a promising strategy for developing novel therapeutics for cancer treatment.
Discover more in this new App Note from Agilent entitled ‘Rapid Bioenergetic Functional Screening of Anticancer Drug Candidates’.
Download the App Note to learn:
- How the Agilent Seahorse XF Real Time ATP rate assay provides a simple robust workflow that can identify metabolic targets for drug discovery.
- How it can identify metabolic target pathways to be investigated during cancer drug discovery.
- About the dedicated analytic software as a direct way to quantitate and compare the metabolic response of cancer cells to chemicals or genetic modification and differentiate mitochondrial and glycolytic energetic metabolism.