Oncology

Cancer Research UK’s innovation engine, Cancer Research Horizons, and Newcastle University, have agreed an extension of their strategic drug discovery alliance with Astex Pharmaceuticals.  The alliance will continue to focus on the discovery of potential new cancer drugs with associated biomarkers, with the aim of providing an innovative route to the development of more effective […]

Cancer is supported by complex ecosystems within the body which can be disrupted by cutting-edge new treatments and cures, cancer researchers have concluded.  The Institute of Cancer Research, London, and The Royal Marsden NHS Foundation Trust have revealed plans to direct research against the cells, signals and immune response in the tissue environment that nurtures […]

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates.  This week started with World Diabetes Day on 14 November and concluded with the start of World Antimicrobial Awareness Week, which aims to […]

News round-up for 14-18 November by DDW Digital Content Editor Diana Spencer.  This week started with World Diabetes Day on 14 November and concluded with the start of World Antimicrobial Awareness Week, which aims to improve education and understanding of the growing issue of antimicrobial resistance.  There were also exciting developments in the field of […]

This is the latest episode of the free DDW podcast, “The next steps in the fight against cancer”. It covers two articles written for Volume 22, Issue 4 – Fall 2021 of DDW. They are called “Accelerating research: the path forward for treating rare cancers” and “Inside combination immunotherapies for cancer”. RareCan is a new […]

New research has found variable voltages in the membranes of breast cancer cells, revealing clues about how they grow and spread. The study, led by Imperial College London and The Institute of Cancer Research, London, could help us better understand how cancer cells ‘decide’ when to multiply and where to spread to. When cells become […]

Triumvira Immunologics has revealed positive clinical data from its ongoing TACTIC‑2 Phase I/II trial of TAC01-HER2 in patients with human epidermal growth factor receptor 2 (HER2) positive solid tumours.  These interim data demonstrate that TAC01-HER2 is well-tolerated and clinical activity was observed in the two higher dosing cohorts, with a 67% disease control rate in cohort […]

DynamiCure has dosed the first patients in its Phase I clinical trial evaluating the first of the company’s two anti-CD93 monoclonal antibody candidates, DCBY02, in adults with a wide range of advanced cancers.  CD93 is a novel target downstream of VEGF-A (vascular endothelial growth factor) that has been shown to play a critical role in […]

An experimental therapeutic cancer vaccine induced immune system responses that led to significant tumour regression in mice, according to investigators from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.    The researchers found that intravenous (IV) administration of the vaccine SNAPvax boosted the number of cytotoxic T cells […]

New research about how cancer-related proteins bind copper ions opens up potential new drug targets to treat cancer.   Studies have shown that the level of copper in tumour cells and blood serum from cancer patients is elevated, and the conclusion is that cancer cells need more copper than healthy cells. Higher levels of copper also […]