Screening

This is the latest episode of the free DDW podcast, “Mass spectrometry and CRISPR are pillars of drug discovery”. It covers two articles written for Volume 23, Issue 1 – Winter 2021/22 of DDW. They are called “How ASMS offers more than seeing what sticks” and “CRISPR screening in the third dimension”. In the first […]

The latest sponsored DDW Sitting Down With podcast is now available. It features Dr Michael Morton, Director and Co-founder, ApconiX, and Dr Kimberly Rockley of ApconiX, who discuss the benefits of early ion channel screening. The podcast covers the hERG ion channel and its importance in cardiac safety screening in drug discovery.  Morton and Rockley […]

The latest sponsored DDW Sitting Down With podcast features Dr Michael Morton, Director and Co-founder, ApconiX, and Dr Kimberly Rockley of ApconiX who discuss the benefits of early ion channel screening. The podcast covers the hERG ion channel and its importance in cardiac safety screening in drug discovery.  Morton and Rockley outline the options available, […]

Avtar Singh is a Senior Scientist in the Cell and Tissue Genomics Department at Genentech, where he develops new approaches for image-based screening and high-throughput biological discovery. DDW’s Megan Thomas spoke with Singh about SLAS2023, where he presented Image-based screening of pooled genetic libraries. MT: Why is SLAS2023 a prime space for you to share […]

Cresset Discovery and the University of Exeter have entered a collaboration to discovery novel antimicrobial drugs.  Cresset Discovery will use virtual screening to identify promising new candidates, building on research led by Dr Stefano Pagliara.  Virtual screening enables chemists to explore new chemical space, discover diverse chemotypes and generate new IP.  Antimicrobials play a fundamental […]

Orbit Discovery and start-up SanegeneBio have entered into a Master Service Agreement to identify tissue-specific delivery of a wide range of RNA therapeutics.  The agreement covers activities ranging from hit ID to cell-based internalisation studies, with an option for Sanegene to further develop the hits resulting from the screening activities.  Orbit’s technology enables the screening […]

Scientists showcase how the concentration of chemicals in droplets can be efficiently controlled by running experiments in the tiniest of cell cultures. These findings could be useful for more effective drug screening and cell-based analysis. Droplet-array sandwiching technology (DAST) lets one use droplets as tiny reaction chambers or cell culture media. In a recent study, […]

This paid-for advertorial by Bio-Rad appeared in the DDW ebook – Innovating in the lab: an essential guide to drug discovery technology. In the following article Richard J Cuthbert, PhD, Global Commercialisation Product Manager, Flow and Antibodies, Bio-Rad Laboratories examines the rise of flow cytometry as a screening tool. In recent years, the use of flow cytometry in drug […]

Download this guide from Abcam to learn more about: How multiplexing generates more insightful data The key principles, benefits and limitations of different multiplex assays How to select the most suitable multiplex assay for your screening program Click here to download

Monitoring wastewater for SARS-CoV-2 – or Coronavirus as it is more commonly known – can be a valuable data resource for an effective Covid-19 management. However, there are several challenges involved in detecting biological parameters in wastewater. Fortunately, there are also several solutions available to overcome them. Wastewater can be a carrier medium of SARS-CoV- […]