A new Guide ‘The biologics researcher’s mini-guide to screening candidates with nanoDSF’ is now available from NanoTemper.
Among the most common critical quality attributes (CQAs) for early developability assessment is thermal stability. One particular tool for assessing thermal stability with high resolution is nano-differential scanning fluorimetry (nanoDSF).
Read this mini-guide to learn:
- How nanoDSF uses your protein’s intrinsic fluorescence to determine its melting temperature, Tm and onset of melting, Ton
- Why high-resolution unfolding data is critical for obtaining stability information about your mAbs
- What some real-life examples of nanoDSF data look like, and what to look for in your own samples
