Covid-19

#Covid-19 #Immunology / Virology & Vaccines

Professor Sarah Gilbert wins award for her work on the Oxford vaccine

The lead researcher on the Oxford vaccine team, Professor Gilbert is Professor of Vaccinology in the Nuffield Department of Medicine at the University of Oxford. She is the Oxford Project Leader for ChAdOx1 nCoV-19, a vaccine against the novel coronavirus, SARSCoV-2, with approval for use in many countries around the… Read More

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#AstraZeneca #Covid-19 #Immunology / Virology & Vaccines #Pfizer #Study

Study shows effectiveness of one dose of COVID-19 vaccine in over 80s

Interim study results show the effectiveness of one dose of the Pfizer-BioNTech and Oxford-AstraZeneca vaccines in preventing hospitalisation of people in their 80s with multiple comorbidities. The AvonCAP study results are by researchers from the University of Bristol, University Hospitals Bristol and Weston NHS Foundation Trust (UHBW) and North Bristol… Read More

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#Covid-19 #Immunology / Virology & Vaccines #Life sciences

Despite COVID-19, Swedish life science companies in growth mode

A new survey conducted by SwedenBIO shows that Swedish life science companies are more confident about future growth than they were before COVID-19, with 80% planning for new hires and expansion. The survey shows a major upswing in the industry, following on from similar reports a year ago which demonstrated… Read More

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Doctor prepares vaccine
#Covid-19 #Immunodeficiency #Immunology / Virology & Vaccines

New study on vaccine responses for impaired immune systems

A new UK study by Octave seeks to understand the immune response to COVID-19 vaccinations in patients with certain immunosuppressed conditions, including cancer. Funded by the Medical Research Council (MRC), researchers from the Universities of Glasgow, Birmingham (sponsors), Oxford, Liverpool, Imperial College London and Leeds Teaching Hospitals NHS Trust will… Read More

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#Biotherapeutics #Cell culture #Covid-19

Grant given to develop single and multi-organ models for COVID-19 research

CN Bio has received a grant from Innovate UK to develop human-relevant single and multi-organ microphysiological systems (MPS) to advance investigations into SARS-CoV-2 infection and advance 3D lung cell culture models to accelerate drug discovery. The grant will be spent developing and testing advanced cell culture models that represent different… Read More

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#Big pharma #Biopharmaceuticals #Biotechnology #Covid-19 #Vaccines

Supply chains key to successful COVID-19 vaccine roll-out 

Resilience in pharma and biotech supply chains is essential for the roll out of the Covid-19 vaccine, says Karl Lauri, ERP/MRP software manufacturer and distributor MRPeasy.com.  While the pandemic has highlighted the strength of the UK’s pharmaceutical and biotechnology sector, it has also shed light on the vulnerabilities of intricate, geographically extended and… Read More

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#Assay development optimisation & technology #Covid-19 #Immunology / Virology & Vaccines

Bio-Rad launches new SARS-CoV-2 serology assay panel

Bio-Rad’s Bio-Plex Pro Human IgG SARS-CoV-2 N/RBD/S1/S2 4-Plex Panel is a ready-to-use, qualitative multiplex immunoassay panel which has been designed to provide quick, precise detection of IgG antibodies against four SARS-CoV-2 antigens. This “provides useful information about natural exposure rates in a population or about vaccine immunogenicity,” said Candice Cox,… Read More

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#Biopharmaceuticals #Covid-19 #Podcast #Therapeutics

How critical is the part therapeutics in the COVID-19 pandemic? – podcast

The latest DDW Sitting Down With podcast features Guy Goldberg, Chief Business Officer of RedHill Biopharma. RedHill Biopharma  is a biopharmaceutical company that recently announced the dosing of the first patient in its US Phase II/III study of orally-administered RHB-107 (upamostat), an investigational new drug for patients with symptomatic COVID-19… Read More

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#Anti-virals #Covid-19 #Interferons #Therapeutics

Inventor of synthetic Interferon discusses potential against COVID-19

ILC Therapeutics, a biotech company based in Scotland, is developing a synthetic Interferon which has shown great promise against COVID-19 in laboratory testing and will enter clinical trials later this year. It will be, says the company, the first synthetic Interferon based on the most prominent activities of the natural… Read More

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#Clinical trials #Covid-19 #Immunology / Virology & Vaccines

COVID-19 vaccine pill a possibility?

Professor Sarah Gilbert, head of the team behind the Oxford AstraZeneca COVID-19 vaccine, has told UK MPs that there is a possibility the vaccine could be taken orally and perhaps also via a nasal spray. Reported in The Guardian newspaper today, she was asked by MP Graham Stringer how the… Read More

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#Covid-19 #Immunology / Virology & Vaccines

Pfizer and AstraZeneca COVID-19 vaccine working, suggests Scottish study

The study is the first to describe across an entire country the effect of the Pfizer and Oxford-AstraZeneca jabs in the community on preventing severe illness resulting in hospitalisation. Previous results about vaccine efficacy have come from clinical trials. Hospitalisation drop By the fourth week after receiving the initial dose,… Read More

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#Clinical trials #Covid-19 #Immunology / Virology & Vaccines

Sanofi and GSK start new Phase II study of their COVID-19 vaccine candidate

Sanofi and GlaxoSmithKline (GSK) have begun a new Phase II study with 720 volunteers aged 18 and over to select the most appropriate antigen dosage for Phase III evaluation of their adjuvanted recombinant protein COVID-19 vaccine candidate. “Over the past few weeks, our teams have worked to refine the antigen… Read More

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#Biopharmaceuticals #Covid-19 #Therapeutics

RedHill Biopharma: first patient dosed in US Phase II/III COVID-19 RHB-107 study

RedHill Biopharma, a specialty biopharmaceutical company, has announced that the first patient was dosed in its US Phase II/III study of orally-administered RHB-107 (upamostat)[i], an investigational new drug for patients with symptomatic COVID-19 who do not require hospital care. Dror Ben-Asher, RedHill’s CEO said: “RedHill is rapidly advancing two Phase… Read More

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#Clinical trials #Covid-19 #Human trials #Immunology / Virology & Vaccines

World’s first coronavirus Human Challenge study receives ethics approval

The UK will be the first country in the world to run a COVID-19 human challenge study, following approval from the UK’s clinical trials ethics body. Backed by a £33.6 million UK government investment, the first-of-its-kind study for this virus will involve establishing the smallest amount of virus needed to… Read More

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#Covid-19 #Diagnostics #Drug development

BioIVT unveils COVID-19 panel to boost vaccine-generated immune response research

BioIVT, provider of research models and services for drug and diagnostic development, has introduced its COVID-19 Vaccination Panel, composed of pre- and post-vaccination serum or PBMC samples, to enable researchers to study blood donors’ vaccine-generated immune response. BioIVT has been providing more than 300 clients with biospecimens to support the… Read More

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#Cell and gene therapy #Immunology / Virology & Vaccines #mRNA

Evonik strengthens strategic partnership with BioNTech on COVID-19 vaccine

Evonik is investing in the short-term expansion of its specialty lipids production which are essential for mRNA-based COVID-19 vaccines. Commercial lipid quantities are to be produced at Evonik’s Hanau and Dossenheim sites in Germany as early as the second half of 2021 as part of a strategic partnership with vaccine… Read More

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