Author Archives: Megan Thomas

#AI / data analytics / healthtech / informatics #Amazon Web Services (AWS) #Artificial intelligence (AI) #Drug development #Drug discovery #Generative AI

Webinar: The benefits of generative AI in drug discovery

In this webinar, discover how high-performance computing (HPC) and AI are being used to screen out potentially dangerous drugs, improve the identification of drug candidates, and develop new therapeutic compounds. It can take years, and cost billions, to get new drugs approved for clinical use, but technological… Read More

Webinar date:
Supported by Amazon Web Services and NVIDIA
#News

#Biotechnology #Cancer research #Clinical trials #Drug development #Drug discovery #Drug targets #Opinion #Podcasts

The DDW Podcast: 2024 in review

As 2024 draws to a close, DDW’s Multimedia Editor and podcast host Megan Thomas rounds up all the free editorial episodes of the DDW podcast that were released. You can find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts. DDW Highlights Innovative. Evolving. Developing. Busy. These… Read More

#News

IgE antibodies
#Antibodies #Bifunctional medicine #Cancer research #Funding #Investment #Ottimo Pharma

Bifunctional medicines to extend the lives of cancer patients

Ottimo Pharma has completed a Series A financing round of over $140 million. The financing will accelerate the lead asset, Jankistomig, a first-in-class PD1/VEGFR2 bifunctional antibody for multiple solid tumour indications, in both IV and SC forms as well as a pipeline of follow-on bifunctional assets. The round was led… Read More

#Business & Investment #Cancer Research #Editor's Choice #News

Blood samples in lab
#blood #Clinical trial #Fc-Fusion proteins #Proteins #Rare disease #Thrombotic diseases

First patients dosed in thrombolytic drug trial

TargED Biopharmaceuticals, a biotechnology company focused on developing improved treatments for thrombotic diseases, has dosed the first participant with TGD001. TGD001 is a thrombolytic designed to break down clots of all sizes and compositions – from large clots which cause AIS, down to ‘micro-clots’ which cause conditions such as the… Read More

#News

Lab automation
#Automation / robotics #Events #Lab technology #SLAS2025 #Translational chemistry

Uncover curiosity to breakthroughs with DDW at SLAS2025

DDW has added Fatah Kashanchi, PhD, Professor, George Mason University and Heather Branscome, MS, PhD, Senior Scientist, ATCC to its track, Concept to Cure: Curiosity and Lab Automation in Drug Discovery at SLAS2025 (25-29 January 2025, San Diego, USA). Heather Branscome Fatah Kashanchi This free programme, which… Read More

#News

#Bill & Melinda Gates Foundation #Funding #Genetic medicines #Sickle cell disorder (SCD) #Tessera Therapeutics

Investment to develop in vivo genetic treatment for sickle cell disease

Tessera Therapeutics, a biotech developing a new approach to genome engineering, has entered into an agreement with the Bill & Melinda Gates Foundation to jointly fund the company’s in vivo programme for sickle cell disease (SCD). The funding includes an initial investment, with potential total investment of up to $50… Read More

#News

#Artificial intelligence (AI) #Automation / robotics #Events #Lab technology #SLAS2025

SLAS2025 Student Poster Award finalists announced

The Student Poster Award finalists for SLAS2025, taking place in San Diego, US, from 25-29 January 2025, have been confirmed. Visit these next-gen scientists working with cutting-edge automation to accelerate their discoveries and meet the future of the industry. Lan Mi, Graduate Student (University of Massachusetts, Amherst) Mi is presenting… Read More

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AI concept
#Artificial intelligence (AI) #Cradle #Drug discovery #Funding #Machine learning #Protein engineering

Generative AI unlock the impact of engineered biology

Cradle, an AI-powered platform for protein engineering, has raised $73m in Series B funding to respond to rising demand in R&D intensive industries. This funding takes the total raised to date over $100m. The round was led by IVP with participation from previous investors Index Ventures and Kindred Capital. Proteins… Read More

#Business & Investment #News

#AI / data analytics / healthtech / informatics #Amazon Web Services (AWS) #Artificial intelligence (AI) #Drug development #Drug discovery #Generative AI

Register now: The benefits of generative AI in drug discovery

In this webinar, discover how high-performance computing (HPC) and AI are being used to screen out potentially dangerous drugs, improve the identification of drug candidates, and develop new therapeutic compounds. It can take years, and cost billions, to get new drugs approved for clinical use, but technological… Read More

Webinar date:
Supported by Amazon Web Services and NVIDIA
#News

The benefits of generative AI in drug discovery

It can take years, and cost billions, to get new drugs approved for clinical use, but technological advances are transforming drug discovery and development. The growing shift towards artificial intelligence (AI), including generative and predictive AI, can reduce the amount of time and money it takes to develop new drugs. Read More

Webinar date:
Supported by Amazon Web Services and NVIDIA
#Webinars

#AACR #Cancer research #Clinical trials #Monotherapy #Recursion #Solid tumours

Encouraging response for monotherapy dose-escalation study

Recursion has reported initial monotherapy dose-escalation data from the Phase I/II study (ELUCIDATE) of REC-617, a selective CDK7 inhibitor, in advanced solid tumours. These results were presented after market close at an AACR Special Conference in Cancer Research. “Cell cycle dysregulation and transcriptional ‘addiction’ are both hallmarks of many aggressive… Read More

#Cancer Research #News

FDA
#Clinical trial #Drug discovery #FDA #Regulatory #SpliceBio #Stargardt disease

First-ever FDA IND for a protein splicing gene therapy

The US Food & Drug Administration (FDA) has cleared an investigational new drug (IND) application for SpliceBio’s lead programme SB-007, a clinical-stage therapeutic addressing the root genetic cause of Stargardt disease with the potential to treat all patients across all ABCA4 mutations. The SpliceBio study uses protein splicing to address… Read More

#News #Regulatory #Trending News

#Collaboration #Deep Science Ventures #Fibrosis #Finance #General Inception #Therapeutics

Venture partners create fibrosis-focused therapeutics company

Venture studios Deep Science Ventures and General Inception have announced plans to create a company focused on developing novel treatments for fibrosis. Science Ventures and General Inception’s European arm, Igniter Europe, aim to establish a company dedicated to overcoming current bottlenecks in fibrosis therapeutics by developing a novel concept and… Read More

#Business & Investment #News

#CAR-T #Cell and gene therapy #Cell therapy #Gene therapy

New DDW Highlights episode: 16 December 2024

The latest episode of the DDW Highlights podcast is now available to listen to and watch below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. It’s been a big week for cell and gene therapies… Read More

#News

#DDW Highlights podcast

DDW Highlights: 16 December 2024

The latest episode of the DDW Highlights podcast is now available to listen to and watch below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. It’s been a big week for cell and gene therapies (CGTs) as… Read More

#Podcasts

#Animal models #Drug development #Drug discovery #The Jackson Laboratory #Vodcast

New vodcast on AI-powered home cage monitoring

The latest sponsored DDW Sitting Down With vodcast features Michael Ellis, Senior Director of R&D at The Jackson Laboratory (JAX), and Timothy Robertson, CEO of TLR Ventures and Leader of the Digital In Vivo Alliance to introduce their new digital home cage monitoring system, Envision. Both Ellis and… Read More

#News