Author Archives: Megan Thomas

Human liver
#American Association for the Study of Liver Diseases (AASLD) #DNA #Epigenomics #HBV #Liver disease #Tune Therapeutics #Viral hepatitis

Preclinical data suggests functional cure for HBV

Epigenome editing company Tune Therapeutics has showcased new data at the American Association for the Study of Liver Diseases (AASLD) conference, in support of its drive to develop a lasting, functional cure for chronic Hepatitis B Virus (HBV). Tune presented its lead HBV programme at the 2023 iteration of the… Read More

#News

Molecules
#AI / data analytics / healthtech / informatics #Amazon Web Services (AWS) #Artificial intelligence (AI) #Drug development #Drug discovery #Generative AI

Learn about the benefits of generative AI in drug discovery

In this webinar, discover how high-performance computing (HPC) and AI are being used to screen out potentially dangerous drugs, improve the identification of drug candidates, and develop new therapeutic compounds. It can take years, and cost billions, to get new drugs approved for clinical use, but technological… Read More

Webinar date:
Supported by Amazon Web Services and NVIDIA
#News

#Dementia #Genetics / genomics #Neurodegenerative disorders #Vesper Bio

POC study initiated for frontotemporal dementia treatment

Vesper Bio has initiated a Phase Ib/IIa Proof of Concept (POC) study of its lead candidate VES001 for frontotemporal dementia. The SORT-IN-2 study will evaluate VES001 in patients with mutations in their progranulin-coding gene (GRN), which are causal for FTD(GRN). FTD(GRN) is an early onset degenerative brain disease which is… Read More

#News

Human brain
#Acquisition #CNS #Excessive Daytime Sleepiness (EDS) #Narcolepsy #Neuraxpharm #Neuroscience #TG Therapeutics

Narcolepsy acquisitions to boost Neuraxpharm’s CNS reach

Pharmaceutical company Neuraxpharm, focused on the treatment of central nervous system (CNS) disorders, has acquired Provigil (modafinil) and Nuvigil (armodafinil), both of which are indicated for the treatment of Excessive Daytime Sleepiness (EDS) in adults with narcolepsy. Neuraxpharm has acquired these products in most markets outside the US, excluding the… Read More

#Business & Investment #News

#Astex Pharmaceuticals #Bioorthogonal chemistry #Click chemistry #Cognitive impairment #Covid-19 #Drug discovery #Life sciences #Long Covid #Molecular Biology #Neuroscience #Public health

Podcast: Innovative approaches to improving drug discovery

This is the latest episode of the free DDW narrated podcast, titled “Innovative approaches to improving drug discovery”, which covers three articles written for DDW Volume 24 – Issue 2, Spring 2023 of DDW. They are called: Post-Covid cognitive impairment: a new target for drug development?, Sitting Down… Read More

#News

#Narrated podcasts

Innovative approaches to improving drug discovery

This is the latest episode of the free DDW narrated podcast, titled “Innovative approaches to improving drug discovery”, which covers three articles written for DDW Volume 24 – Issue 2, Spring 2023 of DDW. They are called: “Post-Covid cognitive impairment: a new target for drug development?“, “… Read More

#Podcasts

#Artificial intelligence (AI) #Drug development #Drug discovery #Omics #RNA

Omics, mRNA and AI: Your top 10 reads of 2024

What were the trending topics of the year? Here, we run through DDW’s most read articles of 2024. 10: The future outlook for mRNA therapies In this article for the Spring 2024 issue, DDW Editor Reece Armstrong explores the potential and future opportunities for mRNA-based therapies. 9: Key… Read More

#News

Brain physiology
#Amyotrophic lateral sclerosis (ALS) #Artificial intelligence (AI) #Longitude Prize #Machine learning #Motor neuron disease #Neurology #Neuroscience

Third global Longitude Prize to be launched in 2025 focusing on ALS

The Longitude Prize series from Challenge Works will launch the Longitude Prize on amyotrophic lateral sclerosis (ALS) in Spring 2025. The next installment in the prize series follows the success of the Longitude Prize on antimicrobial resistance (AMR), won in 2024 by Sysmex Astrego’s PA-100 AST system, and the Longitude… Read More

#News

B-cells in multiple myeloma
#Cancer immunotherapy #FDA #MAIA Biotechnology #Paediatrics #Rare disease

Telomere-targeting agent granted Rare Pediatric Disease designation

The US Food and Drug Administration (FDA) has designated MAIA Biotechnology’s immunotherapy THIO for the treatment of paediatric-type diffuse high-grade gliomas (PDHGG) as a drug for a rare paediatric disease. “THIO is a versatile anti-cancer agent that has demonstrated positive results in multiple difficult to treat cancer types, including paediatric… Read More

#Cancer Research #News

Gene therapy concept
#Blood cancer #CAR-T #Cell therapy #Regenerative Medicine #Stem cells #Tune Therapeutics

Unlocking the future of medicine with cell therapy

Nathan Yee, Senior Director of CMC Portfolio Strategy at Tune Therapeutics, and Lucas Thompson, Senior Director of Research at Tune Therapeutics, discuss the opportunities and challenges in cell therapy. Cell therapy is a transformative medical approach that harnesses living cells as therapeutic agents and has demonstrated the potential to address… Read More

#Cancer Research #Exclusive Content #Opinion

#Autoimmune disease #Clinical research #Sjögren’s disease #T cell

Researchers find existing drug could treat Sjögren’s disease

Researchers are closer to understanding what drives the autoimmune disorder Sjögren’s disease, thanks to new discoveries about the role of calcium signalling, regulatory T cells, and interferon. The study, led by scientists at NYU College of Dentistry and NYU Grossman School of Medicine, was published in Science Translational Medicine. Read More

#News

#Business #Financing #Fundraising #Investment

Listen now: Last DDW Highlights episode of 2024

The latest episode of the DDW Highlights podcast is now available to listen to and watch below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. As we approach the end of 2024, it’s great to see that… Read More

#News

#DDW Highlights podcast

DDW Highlights: 23 December 2024

The latest episode of the DDW Highlights podcast is now available to listen to and watch below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. As we approach the end of 2024, it’s great to see that… Read More

#Podcasts

mRNA
#Circio Holding #circular RNAs #DNA #Funding #mRNA #Norway #RNA #Viral vectors

NOK 10.7 million supports circular mRNA technology

Biotechnology company Circio Holding has secured approximately NOK 10.7 million (€907.4k) in financing to support the development of its circVec circular mRNA technology. The major allocations in the financing were to existing shareholders Høse AS and Bækkelaget Holding AS, and new shareholders Star Kapital AS (v/ Tom A Thorsen) and… Read More

#News

Breast cancer cell
#Breast cancer #Cancer research #Gene mutation #National Institute for Health and Care Excellence (NICE) #Regulatory

NICE approves first ESR1-mutated metastatic breast cancer drug

Final draft guidance from the UK’s National Institute for Health and Care Excellence (NICE) recommends the use of elacestrant, the first tailored treatment for locally advanced and metastatic breast cancer with mutations in the ESR1 gene. Specifically, the drug will be available on the NHS to treat post-menopausal women, and… Read More

#Cancer Research #News #Regulatory