Investigators have found evidence that the cholesterol-lowering drug lapaquistat could be an effective treatment for Cryptosporidium, an intestinal parasite. Researchers at the Francis Crick Institute in London, UK, have mapped the human metabolic pathways that Cryptosporidium requires to survive. The scientists say that shutting down… Read More
Researchers have discovered a way of using engineered brain parasites to deliver treatments for neurological conditions across the blood-brain-barrier. The study – led by the University of Glasgow in collaboration with Tel Aviv University and an international team of researchers – represents an exciting new field… Read More
Anti-malarial drug artesunate-mefloquine has been proven to be effective against another devastating parasitic disease, thanks to research at the Institute of Tropical Medicine (ITM). Schistosomiasis affects over 200 million individuals around the world, predominantly in poor populations living in rural areas of sub-Saharan Africa. Read More
The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. It’s been a fascinating week in drug discovery, as AstraZeneca announced that its Phase III trial… Read More
News round-up for 3-7 July by DDW Digital Content Editor Diana Spencer. It’s been a fascinating week in drug discovery, as AstraZeneca announced that its Phase III trial of datopotamab deruxtecan did not meet its second primary endpoint and saw an 8% drop in its stock… Read More
Scientists have discovered a new class of compound that is potentially active against trypanosome parasites that cause human African trypanosomiasis (or sleeping sickness) and Chagas disease. The findings – led by researchers at the University of Glasgow and Novartis Global Health (formerly Novartis Institutes for Tropical… Read More
