Novel candidates

Destiny Pharma, a UK-based clinical stage biotechnology company focused on the development of novel medicines to prevent life threatening infections, has published landmark XF-73 clinical data in the US peer reviewed journal Infection Control & Hospital Epidemiology.    The paper was published by Dr. Julie Mangino (Professor Emeritus, Division of Infectious Diseases, at The Ohio State […]

The newest addition to the free DDW podcast is the In Conversation With series, where DDW speaks with members of the drug discovery industry about their work and how it helps turn science into business.    In this latest episode, DDW’s Megan Thomas speaks with Dr Mark Varney, the Chief Scientific Officer at PsychoGenics, who discusses […]

Ori Biotech and the Cell Therapy Manufacturing Center (CTMC) have partnered to accelerate process development, clinical implementation, and commercialisation of novel cell therapies.   The partnership will combine Ori’s technology platform with CTMC’s manufacturing capabilities and, in the first instance, will focus on a cell therapy invented by Dr Sattva Neelapu, Professor of Lymphoma/Myeloma at MD […]

TARA Biosystems, a biotechnology company using human biology and data for cardiac drug discovery, has collaborated with Scipher Medicine, a precision medicine company. The collaboration will address a critical unmet need for effective therapeutics in cardiac laminopathies.   Cardiac laminopathies, associated with mutations in the LMNA gene, can result in electrical and mechanical changes in the heart. These […]

EQRx and Exscientia are collaborating to combine the AI capabilities of Exscientia to accelerate the discovery of small molecule therapeutic drug candidates and expand EQRx’s pipeline of novel therapies. This collaboration is focused on creating improvements in the traditional drug discovery and development processes by improving the probability of success through each company’s capabilities to […]

New research led by Robert Gerszten, Chief of the Division of Cardiovascular Medicine at Beth Israel Deaconess Medical Center (BIDMC) sheds new light on the genetic risk factors that make individuals more or less susceptible to severe COVID-19. The findings, published in a letter in the New England Journal of Medicine, illuminate the mechanisms underlying […]

By André Julião, Agência FAPESP Researchers based in Brazil and the US have completed the first-ever mapping exercise to profile the toxins produced by tube-dwelling anemones, or cerianthids, a family of marine animals belonging to the same phylum (Cnidaria) as sea anemones, jellyfish and corals. The analysis revealed that the toxins that can act on […]

The UK BIA Antibody Taskforce, a UK consortium developing antibodies for treating COVID-19 has reached a major milestone – the identification of differentiated antibody combinations that will be taken forward for further development as an antibody ‘cocktail’. The Taskforce developed an accelerated and rigorous multifaceted approach to create a pool of over 600 novel candidates […]