National Institutes of Health (NIH)

US science protest
#Drug discovery #Funding #National Institutes of Health (NIH) #Politics #United States

Researchers challenge NIH screening of scientific research grants

US researchers have filed a class action lawsuit challenging the National Institutes of Health’s (NIH) policy of blocking grants to censor views it disagrees with, on everything from DEI to gender identity to climate change.  The plaintiffs are represented by the American Civil Liberties Union, the ACLU… Read More

#Editor's Choice #News #Trending News

Organoid
#Disease modelling #National Institutes of Health (NIH) #New approach methodologies (NAMs) #Organoids

First-of-its-kind organoid centre to reduce reliance on animal models

A new US Standardized Organoid Modeling (SOM) Center will be dedicated to using cutting-edge technologies to develop standardised organoid-based new approach methodologies (NAMs).   With contracts totalling $87 million for the first three years, the centre will be housed at the Frederick National Laboratory for Cancer Research (FNLCR),… Read More

#News

#Digital biomarkers #Monument Therapeutics #National Institutes of Health (NIH) #Neuroscience #Schizophrenia

Monument Therapeutics partners on novel treatment for schizophrenia

Monument Therapeutics and the Foundation for the National Institutes of Health (FNIH) will evaluate MT1988, in development for cognitive impairment associated with schizophrenia, in a proof-of-principle clinical trial.  Many individuals begin to show signs of schizophrenia months or even years before receiving a diagnosis, referred to as… Read More

#Business & Investment #News

#BioMed X #Biomedical research #Funding #National Institutes of Health (NIH) #United States

XBridge Program launches for researchers impacted by NIH cuts

BioMed X, an independent biomedical research institute based in Heidelberg, Germany, has announced the launch of its XBridge Program, a fast-track initiative designed to support US-based biomedical researchers impacted by the current NIH funding gaps, hiring freezes, and grant terminations.   The programme is a kind of matchmaking… Read More

#News

#Funding #National Institutes of Health (NIH) #Politics #Research and development

From the Editor: Science under threat

It seems rather obvious, and somewhat unfair to DDW’s readers – considering how much he has been in the news recently – to talk more about President Donald Trump and specifically his decision to cut billions of dollars in funding to the National Institutes of Health (NIH).  The decision… Read More

#Exclusive Content #Opinion

Vaccine
#Immunology / Virology & Vaccines #National Institutes of Health (NIH) #NIAID #Phase I trial

Clinical trial represents a step towards a vaccine for Lassa fever

A clinical trial of a candidate vaccine to prevent Lassa fever has begun enrolling participants at the University of Maryland School of Medicine, Baltimore.   Lassa fever is a viral haemorrhagic disease that can be fatal and causes permanent hearing loss in up to one-third of those who… Read More

#Editor's Choice #News

National Institutes of Health
#Funding #National Institutes of Health (NIH) #Politics

NIH cuts billions in funding for medical research

The Trump administration in the US has announced plans to cut billions of dollars in funding for costs related to medical research funding in universities, hospitals and other scientific institutions.  These grants include payments for “indirect costs,” defined as “facilities” and “administration”, which cost up to $9… Read More

#News #Trending News

Mosquito
#Immunology / Virology & Vaccines #Monoclonal antibodies #National Institutes of Health (NIH) #Phase II trial

Phase II trial will test monoclonal antibody for dengue

A clinical trial supported by the National Institutes of Health (NIH) is testing an experimental treatment for the effects of dengue, a mosquito-borne viral disease.   The study is supported by NIH’s National Institute of Allergy and Infectious Diseases (NIAID).  It will test the ability of… Read More

#News

Mosquito
#Antibodies #Immunology / Virology & Vaccines #Malaria #Monoclonal antibodies #National Institutes of Health (NIH)

Researchers discover novel class of anti-malaria antibodies

A novel class of antibodies that binds to a previously untargeted portion of the malaria parasite could lead to new prevention methods, according to a study from researchers at the National Institutes of Health (NIH) published in Science.   Of the five species of… Read More

#News

#Autoimmune disease #EVOQ Therapeutics #Funding #National Institutes of Health (NIH)

$2 million in funding for autoimmune nanodisc therapies

EVOQ Therapeutics has received a $2 million grant from the National Institutes of Health (NIH) to advance novel therapies for autoimmune diseases. Dr James Moon, Chief Scientific Officer of EVOQ Therapeutics, said: “This support will enable us to accelerate the development of our platform, which we… Read More

#Business & Investment #News

Enterovirus
#Clinical trial #Monoclonal antibodies #National Institutes of Health (NIH) #Virology

Trial to test monoclonal antibody for virus of growing concern

The National Institutes of Health (NIH) is sponsoring a clinical trial to evaluate the safety of an investigational monoclonal antibody to treat enterovirus D68 (EV-D68), which can cause severe respiratory and neurological diseases such as acute flaccid myelitis (AFM). AFM has emerged in the United States… Read More

#News #Trending News

Microbiome
#Microbiome #National Cancer Institute #National Institutes of Health (NIH) #Oncology #The Francis Crick Institute #vitamin D

Vitamin D boosts ‘good’ bacteria and improves immunity to cancer

Researchers have found that vitamin D encourages the growth of a type of gut bacteria in mice which improves immunity to cancer. The researchers from the Francis Crick Institute, the National Cancer Institute (NCI) of the US National Institutes of Health (NIH) and Aalborg University in… Read More

#Cancer Research #News #Trending News

Antibodies
#Antibodies #Flu #Flu vaccine #Immunology / Virology & Vaccines #Influenza #National Institutes of Health (NIH)

Novel antibodies target ‘dark side’ of influenza virus protein

Researchers at the National Institutes of Health have identified antibodies targeting a hard-to-spot region of the influenza virus, shedding light on the relatively unexplored ‘dark side’ of the neuraminidase (NA) protein head. The antibodies target a region of the NA protein that is common among many… Read More

#Editor's Choice #News

Pathology data for HIV
#Biorepository #Data #HIV #National Institutes of Health (NIH) #Pathology #Proscia #The AIDS and Cancer Specimen Resource

Pathology data to advance discovery for HIV cancer patients 

The AIDS and Cancer Specimen Resource (ACSR), a biorepository of specimens collected from persons living with HIV (PLWH) established in 1994 and funded by the National Institutes of Health, National Cancer Institute, is using software from Proscia to encourage scientific exploration and discovery in cancer in PLWH.  … Read More

#News

CRISPR gene editing
#CRISPR #Funding #Genetics / genomics #National Institutes of Health (NIH) #Neuroscience #Yale University

NIH awards ‘bench-to-bedside’ grant for CRISPR drug development

The National Institutes of Health has awarded the first phase of a roughly $40m grant to Yale University to advance a novel CRISPR-based gene-editing delivery platform for the targeted treatment of neurogenetic diseases. The two diseases being targeted in the project are Angelman syndrome and H1-4… Read More

#News

Influenza
#Immunology / Virology & Vaccines #Influenza #National Institutes of Health (NIH) #Phase I trial

Nanoparticle universal flu vaccine enters Phase I trials

Enrolment in a Phase I trial of a new investigational universal influenza vaccine candidate has begun at the National Institutes of Health’s Clinical Center in Bethesda, Maryland, US. The trial is sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), part of the NIH,… Read More

#News