mRNA

This is the latest episode of the free DDW narrated podcast, “Drug discovery trends: From regulation to embracing AI”, which covers two articles written for Volume 23 – Issue 4, Fall 2022 of DDW. They are called: From the Editor: Law and order and How AI in pharma can live up to the hype. In […]

As demand for mRNA continues to surge, two new facilities have been launched to boost production in Australia and the US. Work is underway at The University of Queensland’s (UQ) BASE facility which has become Australia’s leading provider of mRNA for research and pilot studies since its launch in 2021. The Commonwealth Government’s Medical Research […]

Join DDW for this exclusive free event, Scaling up in vitro transcription: Key results and considerations, which is supported by Thermo Fisher Scientific. In vitro transcription (IVT) can be a complicated reaction. Scaling up this process requires a good understanding of the various reaction parameters that need to be optimised and controlled to give the best result in […]

etherna, an mRNA/LNP technologies company, has announced that Bernard Sagaert has been confirmed as Chief Executive Officer. At the same time Marijn Dekkers, an existing Board Member representing investor Novalis LifeSciences LLC, has been appointed Chairman of the Board.  Sagaert’s appointment follows an interim 12-month period during which he has successfully led the company’s pivot […]

Join DDW for this exclusive free event, Scaling up in vitro transcription: Key results and considerations, which is supported by Thermo Fisher Scientific. In vitro transcription (IVT) can be a complicated reaction. Scaling up this process requires a good understanding of the various reaction parameters that need to be optimised and controlled to give the best result in […]

Join DDW for this exclusive free event, Scaling up in vitro transcription: Key results and considerations, which is supported by Thermo Fisher Scientific. In vitro transcription (IVT) can be a complicated reaction. Scaling up this process requires a good understanding of the various reaction parameters that need to be optimised and controlled to give the best result in […]

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates.  In celebration of the Nobel Prize for Medicine going to two of the early proponents of mRNA technology for creating therapeutics, Katalin Karikó […]

Join DDW for this exclusive free event, Scaling up in vitro transcription: Key results and considerations, which is supported by Thermo Fisher Scientific. In vitro transcription (IVT) can be a complicated reaction. Scaling up this process requires a good understanding of the various reaction parameters that need to be optimised and controlled to give the best result in […]

News round-up for 2-6 October by DDW Digital Content Editor Diana Spencer. In celebration of the Nobel Prize for Medicine going to two of the early proponents of mRNA technology for creating therapeutics, Katalin Karikó and Drew Weissman, this week our round-up highlights the importance of genetics, genomics and gene editing in drug discovery. The […]

The Nobel Assembly at Karolinska Institutet has awarded the 2023 Nobel Prize in Physiology or Medicine jointly to Katalin Karikó and Drew Weissman for their discoveries that enabled the development of mRNA vaccines against Covid-19. In a statement, the Assembly said: “The discoveries by the two Nobel Laureates were critical for developing effective mRNA vaccines […]

Join DDW for this exclusive free event, Scaling up in vitro transcription: Key results and considerations, which is supported by Thermo Fisher Scientific. In vitro transcription (IVT) can be a complicated reaction. Scaling up this process requires a good understanding of the various reaction parameters that need to be optimised and controlled to give the best result in […]

In vitro transcription (IVT) can be a complicated reaction. Scaling up this process requires a good understanding of the various reaction parameters that need to be optimised and controlled to give the best result in terms of mRNA yields and quality. In this presentation, a review of the results from scaling up the IVT reaction from […]

Replicate Bioscience has dosed the first participant in a Phase I trial of its RBI-4000 vaccine for the prevention of rabies. The trial, which marks the first time a human has been dosed with Replicate’s srRNA technology, will serve as a benchmark for utility in this indication and other complex infectious diseases and provide foundational […]

A new Application Note is now available to download from Sartorius BIA Separations. In this App Note, multi-parallel screening of binding conditions on CIM Oligo dT 96-well plates was performed to optimise the dynamic binding capacity (DBC) in the shortest time possible. What you will learn: How to effectively use Monolithic 96-well plates when developing methods. They are […]

In this Application Note, multi-parallel screening of binding conditions on CIM® Oligo dT 96-well plates was performed to optimise the dynamic binding capacity (DBC) in the shortest time possible. What you will learn: How to effectively use Monolithic 96-well plates when developing methods. They are unique on the market in combining the standard well-plate design with monolithic […]

Moderna and Immatics have announced a strategic research and development collaboration to pioneer novel and transformative therapies for cancer patients with high, unmet medical need.   This broad multi-platform collaboration will leverage the scientific expertise and core operational capabilities of both companies, combining Immatics’ TCR platform with Moderna’s mRNA technology, and span various therapeutic modalities including […]