Korea

#AI #Cell and gene therapy #Charles River #Drug discovery #European Commission #European Union #FDA #Immune cells #Korea #Obesity #Personalised medicine #Rare disease #Regulatory

DDW Highlights: 23 December 2025

The latest episode of the DDW Highlights Podcast is now available to listen to below. DDW’s Bruno Quinney narrates five key stories of the previous week to keep DDW subscribers up-to-date on the latest industry news. Last week, a research team found that a hidden molecular switch fuels obesity. Elsewhere, AI-generated… Read More

#Podcasts

#AI #Cell and gene therapy #Charles River #Drug discovery #European Commission #European Union #FDA #Immune cells #Korea #Obesity #Personalised medicine #Rare disease #Regulatory

This week in Drug Discovery (15 – 19 December) 

News round-up for 15 – 19 December by Bruno Quinney, Content Team at DDW.  This week in DDW, a research team found that a hidden molecular switch fuels obesity. Elsewhere, AI-generated antibodies have been tolerated by human immune cells.  The top stories:    Scientists discover hidden molecular switch that… Read More

#News

Obese man measures his waist
#Korea #Obesity

Scientists discover hidden molecular switch that fuels obesity 

A research team from Chonnam National University Medical School, Republic of Korea, discovered a new role of Ret finger protein (RFP) in driving fat cell formation and metabolism.  They found that mice lacking RFP resisted weight gain and had better metabolic profile even on a high-fat diet— highlighting… Read More

#News

Cancer research
#Diabetes #GLP-1 #Korea #Obesity #Phase I trial #Small molecules #Yunovia

Small molecule GLP-1 agonist shows superior tolerability

Yunovia (a subsidiary of Ildong Pharmaceutical Group) has received permission from the Ministry of Food and Drug Safety (MFDS) of Korea to begin a Phase I study for its small molecule glucagon-like peptide-1 (GLP-1) agonist for obesity and diabetes. The Phase I Multiple Ascending Dose (MAD)… Read More

#Editor's Choice #News #Regulatory

Janus kinase 1 protein
#Adverse event #Atopic dermatitis #Dermatology #JAK inhibitor #Korea #Pusan National University

Do JAK inhibitors increase the risk of serious adverse events?

South Korean researchers have found that the use of Janus kinase (JAK) inhibitors as a treatment for atopic dermatitis (AD) is not associated with a greater risk of serious adverse events. While several biologic treatment approaches have been proposed in the recent years for the treatment… Read More

#News

Patient receiving vaccine
#Covid-19 #Covid-19 vaccine #Immunology / Virology & Vaccines #Korea #SARS-CoV-2

Adjuvanted Covid-19 vaccine elicits stronger immune response

Researchers from Korea conducted a clinical trial to assess the immunogenicity and safety of GBP510/AS03 relative to the ChAdOx1-S vaccine. The interim results show that GBP510/AS03 had an acceptable safety profile and induced stronger antibody responses when compared with ChAdOx1-S GBP510 is a recombinant… Read More

#News

Human brain
#Depression #Genetics / genomics #Korea #Major depressive disorder #Mouse models #Neuroscience

Researchers uncover molecular pathways underlying depression

Scientists have discovered the link between gene expression, DNA methylation, and brain structural changes in depression, revealing new potential therapeutic targets. By analysing gene interactions in mice subjected to behavioural tests, the researchers from Korea University Anam Hospital, Konkuk University, and Sahmyook University identified 141 genes… Read More

#News

Damaged DNA
#Biosensors #Cancer research #DNA #Korea #Oncology

Novel biosensor could help optimise cancer treatment

Scientists from Korea have developed a new biosensor that uses fluorescence resonance energy transfer (FRET) to detect DNA double-strand breaks in living specimens in real time. This biosensor has the potential to aid the development of new treatments for DNA damage-related diseases by revealing how our… Read More

#Cancer Research #News

Seoul, South Korea
#Korea #Pharmaceuticals

Korean pharma “booming” survey finds

The results of the survey were revealed ahead of CPHI Korea, which will be held in Seoul, September 28-30. South Korea recovered from the pandemic earlier than many other Asian countries and reported rapid growth in its contract manufacturing industry in the last two years.  In fact, the government… Read More

#News