The most popular method of genetic editing, CRISPR, might not be the safest approach to treat incurable diseases, a new study has highlighted. The study, published by the University of California San Diego and Yale University, suggests small nuclear RNA base editing could be a safer approach… Read More
CAR-T Therapies have revolutionised the field of personalised medicine, especially in oncology. DDW’s Megan Thomas speaks with Dr Blythe Sather, Vice President and Head of Research at Tune Therapeutics, about how genetic tuning will transform the reach for CAR-T therapies, the different diseases that can benefit, and the disruptive technology… Read More
A new technique to clone and reassemble DNA could simplify and lower the cost of making synthetic chromosomes, according to its creators at University of Southern California (USC) Dornsife. Known as ‘CReATiNG’ (Cloning Reprogramming and Assembling Tiled Natural Genomic DNA), the method offers a simpler and… Read More
In a step forward for genetic engineering and synthetic biology, US researchers have modified E coli bacteria to be immune to infection by all natural viruses tested so far. The team used two safeguard methods to prevent the bacteria and their modified genes from escaping into… Read More
The University of California, Davis, has received over $12 million from the National Institutes of Health for the third and final five-year phase of the Knockout Mouse Phenotyping Project (KOMP2). ‘Knockout’ mice are bred in a laboratory with specific genes silenced or ‘knocked out’. They have been valuable tools for… Read More
A one-time treatment for HIV and AIDS may be possible thanks to gene editing, according to research conducted by scientists from Tel Aviv University (TAU). Researchers from Tel Aviv University used CRISPR systems to engineer type B white blood cells into producing HIV-neutralising antibodies in the immune… Read More
This is the latest episode of the free DDW podcast, “What does gene-based medicine have to offer?”. It covers two narrated articles written for Volume 22, Issue 3 – Summer 2021 of DDW. The articles are called “Lipidomics in biomedical research: chance and challenges” and “Exploring gene-based medicine’s true potential”. Read More
The latest free-to-listen DDW podcast episode is titled “Using biotechnology to maximise drug discovery output”. It covers two articles written for Volume 22, Issue 2 – Spring 2021 of the Drug Discovery World Magazine and has been narrated by DDW’s Megan Thomas. These articles are titled: “The important integration of medicinal chemistry in Hit-to-Lead… Read More
By Andrew Myers Throughout the pandemic, infectious disease experts and frontline medical workers have asked for a faster, cheaper and more reliable COVID-19 test. Now, leveraging the so-called “lab on a chip” technology and the cutting-edge genetic editing technique known as CRISPR, researchers at Stanford have created a highly automated… Read More
