Eye health

New study results show that an experimental drug may prevent or slow vision loss in people with diabetes. The researchers at Wilmer Eye Institute, Johns Hopkins Medicine used mouse as well as human retinal organoids and eye cell lines in their investigations. Eye conditions that cause vision loss are common complications of diabetes, affecting nearly […]

This is the latest episode of the free DDW podcast, “A deep dive into the future of ophthalmology”. It covers two articles written for Volume 23, Issue 1 – Winter 2021/22 of DDW. They are called “Innovation, investment and commitment: Genentech’s approach to the future of ophthalmology” and “Innovative delivery of sustained ophthalmic steroids for […]

Evotec has entered a target and drug discovery partnership with Boehringer Ingelheim, focusing on induced pluripotent stem cell (iPSC)-based disease modelling for ophthalmologic disorders.   Context   Millions of people are affected by vision-related diseases worldwide, and there is a high unmet need for novel therapeutic solutions.   The partnership  Through phenotypic screening of human iPSC-derived cells, supported […]

Listen to this article on the DDW Podcast: Professor Sobha Sivaprasad, Professor of Retinal Clinical Studies, UCL Institute of Ophthalmology, and Consultant Ophthalmologist, Moorfields Eye Hospital, UK discusses unmet needs in DME therapeutics and how they could be addressed by sustained release ophthalmic steroids administered with novel suprachoroidal drug delivery methods.  Diabetic eye disease is a growing global […]

Stuart Therapeutics, a clinical stage, ophthalmic therapeutic development company, has announced the topline results of the first in human Phase II clinical trial for its lead drug candidate, ST-100 in patients with dry eye disease.   The trial  The clinical trial, conducted between June and October 2021, was a multi-centre, randomised, controlled, double masked clinical trial to […]

In the UK, a University of Manchester-led team of scientists has discovered that the most common form of adult blindness is probably caused by a failure of at least one of five proteins to regulate the immune system. The breakthrough could one day herald the development of transformative treatments for developing age-related macular degeneration (AMD), […]