Drug resistance

#Alzheimer's #Bacteria #Brain cancer #Cancer immunotherapy #Clinical trial #Drug resistance #Fast Track designation #FDA #Gene therapy #Life sciences #Melanoma #Siren Biotechnology #UK government #University of Sydney

DDW Highlights: 10 February 2026

The latest episode of the DDW Highlights Podcast is now available to listen to below. DDW’s Bruno Quinney narrates five key stories of the previous week to keep DDW subscribers up-to-date on the latest industry news. Last week, innovative therapies showed the way to more effective cancer treatments. Elsewhere, how can… Read More

#Podcasts

#Alzheimer's #Bacteria #Brain cancer #Cancer immunotherapy #Clinical trial #Drug resistance #Fast Track designation #FDA #Gene therapy #Life sciences #Melanoma #Siren Biotechnology #UK #UK government #University of Sydney

This week in Drug Discovery (2 – 6 February) 

News round-up for 2 – 6 February by Bruno Quinney, Content Team at DDW.  This week in DDW, innovative therapies could pave the way to more effective cancer treatments. Elsewhere, how can brain function be improved in Alzheimer’s patients?  The top stories:      Immunotherapy before surgery… Read More

#News

#Bacteria #Drug resistance #University of Sydney

Sugar-targeting antibody could kill drug-resistant bacteria

Sugar molecules found on bacterial cells could offer a target to killing drug-resistant bacteria, scientists suggest.  Researchers have designed antibodies that recognise the sugar found only on bacterial cells, which could underpin a new generation of immunotherapies for multidrug resistant hospital-acquired infections.  The findings, published in … Read More

#News

#Antibiotics #Antimicrobial resistance (AMR) #Antimicrobials #Drug resistance

PACE launches new funding for antimicrobial drug development

PACE, one of the UK’s largest public-private initiatives targeting early-stage antimicrobial drug and diagnostic development, has launched its third round of funding to support innovative projects.  The initiative has announced £6 million ($8 million) in funding for antibacterial treatment innovations, aiming to tackle resistant bacterial infections and… Read More

#News

X-ray showing colon cancer
#Bowel cancer #Drug resistance #Oncology #Organoids #The Institute of Cancer Research

Scientists uncover mechanism behind drug resistance in bowel cancer

Scientists at The Institute of Cancer Research (ICR), London, have discovered what may cause some treatments to stop working in people living with bowel cancer.   The findings could help researchers use information about a person’s cancer to make better use of current treatments and develop more targeted… Read More

#Cancer Research #News

The tumour microenvironment
#Chemotherapy-resistance #Drug resistance #Oncology #The Institute of Cancer Research #Tumour microenvironment (TME)

Study reveals role of the secretome in cancer drug resistance

A new study has shown that non-cancerous cells positioned close to tumours can affect how cancer responds to treatment.   The researchers say factoring in the effects of these cells could improve drug development and provide new insights into the most effective use of existing cancer medications. … Read More

#Cancer Research #Editor's Choice #News

Gold compound
#Drug resistance #Oncology #Ovarian cancer #RMIT University #Solid tumours

Gold-based drug slows tumour growth by 82%

Gold-based drugs can slow tumour growth in animals by 82% and target cancers more selectively than standard chemotherapy drugs, according to new research.  The study published in the European Journal of Medicinal Chemistry reveals a new gold-based compound that’s 27 times… Read More

#Cancer Research #Editor's Choice #News

Cancer cell
#Cancer drug targets #Drug resistance #EMBL European Bioinformatics Institute #Gene mutation #Genetics / genomics #Oncology #Wellcome Sanger Institute

Drug resistance study boosts discovery of next-generation cancer drugs

New research has detailed each type of cancer mutation that causes drug resistance, helping to uncover targets for drug development and identify potential effective second-line therapies. In a new large-scale study, researchers from the Wellcome Sanger Institute, EMBL’s European Bioinformatics Institute (EMBL-EBI), Open Targets, and collaborators… Read More

#Cancer Research #News #Trending News

Prostate cancer cells
#Drug resistance #Oncology #Prostate cancer #The Institute of Cancer Research #The Institute of Oncology Research #The Royal Marsden NHS Foundation Trust

Researchers reverse prostate cancer drug resistance

Prostate cancer’s resistance to treatment can be reversed in some patients by stopping hijacked white blood cells from being ‘pulled into’ tumours, according to new research published in Nature. In an early clinical trial, researchers showed that blocking the messages cancer uses to hijack white blood… Read More

#Cancer Research #News #Trending News

Cancer metastasis
#Cancer drug targets #Cancer research #Drug resistance #Oncology #University of Queensland

Novel inhibitors could become new anticancer therapeutics

University of Queensland (UQ) researchers have identified a novel drug target with the potential to overcome drug resistance and prevent tumour regrowth in cancer patients. The newly identified molecule is not currently a target for treatment, opening the potential for drug development. “Drug resistance… Read More

#Cancer Research #News

Illustration of a virus
#Antivirals #Drug resistance #Immunology / Virology & Vaccines #New York University

Next-generation antivirals could target virus membranes

Researchers have shown that a group of novel molecules inspired by our own immune system inactivates viruses like Zika and chikungunya, and could help overcome antiviral resistance. “We found an Achilles heel of many viruses: their bubble-like membranes. Exploiting this vulnerability and disrupting the membrane is… Read More

#Editor's Choice #News

#Cancer #Cancer research #Cancer vaccine #Chemotherapy #Chemotherapy-resistance #Drug resistance #Epigenetics #Oncology #Personalised medicine

Cancer research drugs: Where is the innovation?

An update on the latest oncology developments by DDW Digital Content Editor Diana Spencer The last month has seen huge strides forward in our understanding of cancers, particularly in how they develop resistance to therapies and how we can ‘outsmart’ them using gene editing or different therapeutic pathways, but also… Read More

#Cancer Research #Editor's Choice #News

Stomach cancer cells
#ATR inhibitors #Cancer #Cancer research #Cancer Research UK #CRISPR #Drug resistance #Gene editing #Genetic study #Stomach cancer #The Institute of Cancer Research

Study reveals how stomach cancers develop drug resistance

Scientists have shown how stomach cancers can develop resistance to a new class of drugs called ATR inhibitors by switching off the activity of two key genes – raising the possibility of outsmarting cancer by predicting drug resistance in advance.  The findings could pave the way for… Read More

#Cancer Research #News