Bowel cancer

Scientists have revealed the inner workings of a key protein involved in a wide range of cellular processes – potentially paving the way for better and less toxic cancer drugs.  Using Nobel Prize-winning microscopy techniques, the researchers revealed how the tankyrase protein switches itself on and off by self-assembling into 3D chain-like structures.  Their study, […]

Cancers can evolve to become more aggressive without relying only on DNA mutations, two major studies have revealed.  The research characterises an extra level of control of cancer gene activity within tumours, which the researchers describe as cancer’s ‘dark matter’.  The two studies showed how a level of gene control called ‘epigenetics’ plays a central […]