Four methods for thermal stability assessment of proteins

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Thermal stability is among the most common critical quality attributes (CQAs) used for early developability assessment of biologics.

In this infographic, learn about four methods for thermal stability assessment of proteins – what they measure, what the data tells you, and their benefits and limitations.

While each provides unique value, the table will help you understand why nanoDSF is the go-to choice for determining the Tms of your therapeutic proteins.

You’ll learn about:

  • The measurement principles of DSC, CD, extrinsic DSF and nanoDSF
  • Which biophysical parameters each method gives you access to
  • The pros and cons of each method compared to each other
  • Why nanoDSF is the preferred method to assess the thermal stability of your therapeutic proteins

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